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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
18323
World Ranking
4175
National Ranking
138

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award

Overview

Steven L. Pelech is affiliated with the University of British Columbia in Canada. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable focus on Molecular Biology, Infectious Diseases, Radiology, Nuclear Medicine and Imaging, Epidemiology, and Biochemistry.

The scientist's work covers several specialized topics, including:

  • SARS-CoV-2 and COVID-19 Research
  • Monoclonal and Polyclonal Antibodies Research
  • Lipid metabolism and biosynthesis
  • Gene expression and cancer classification
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 detection and testing
  • Animal Virus Infections Studies

Steven L. Pelech has been involved in publishing research in several academic venues, with frequent publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Biology of the Cell
  • Vaccines
  • International Journal of Molecular Sciences
  • Blood

The scientist has worked collaboratively with several frequent co-authors, including:

  • Dirk Winkler
  • Lambert Yue
  • Yossef Av-Gay
  • Michael McPhee
  • Neale D. Ridgway

Selected recent papers by Steven L. Pelech include:

  • "A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2" (2021) published in JCI Insight
  • "Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets" (2020) published in Molecular Biology of the Cell
  • "Maternal COVID-19 Vaccination and Its Potential Impact on Fetal and Neonatal Development" (2021) published in Vaccines
  • "Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication" (2022) published in Molecular Biomedicine
  • "Escherichia coli recombinant expression of SARS-CoV-2 protein fragments" (2022) published in Microbial Cell Factories

Best Publications

  • Mitogen-activated protein kinases : versatile transducers for cell signaling

    Steven L. Pelech;Jasbinder S. Sanghera

  • Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase.

    I Clark-Lewis;J S Sanghera;S L Pelech

  • Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.

    Jasmina N. Jovanovic;Fabio Benfenati;Yaw L. Siow;Talvinder S. Sihra

  • Regulation of phosphatidylcholine biosynthesis

    Steven L. Pelech;Dennis E. Vance

  • MAP kinases: charting the regulatory pathways

    Steven L. Pelech;Jasbinder S. Sanghera

  • Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages.

    S L Weinstein;J S Sanghera;K Lemke;A L DeFranco

  • Signal transduction via phosphatidylcholine cycles

    Steven L. Pelech;Dennis E. Vance

  • Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor.

    C L Sutherland;A W Heath;S L Pelech;P R Young

  • An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase.

    N K Mukhopadhyay;D J Price;J M Kyriakis;S Pelech

  • α-Synuclein activates stress signaling protein kinases in THP-1 cells and microglia

    Andis Klegeris;Steven Pelech;Benoit I. Giasson;John Maguire

  • Activation of multiple proline-directed kinases by bacterial lipopolysaccharide in murine macrophages.

    J S Sanghera;S L Weinstein;M Aluwalia;J Girn

  • Identification of Kinase-Phosphatase Signaling Modules Composed of p70 S6 Kinase-Protein Phosphatase 2A (PP2A) and p21-activated Kinase-PP2A

    Westphal Rs;Coffee Rl;Marotta A;Pelech Sl

  • Granulocyte-macrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase.

    Keiko Okuda;Jasbinder S. Sanghera;Steven L. Pelech;Yuzuru Kanakura

  • Fatty acids promote translocation of CTP:phosphocholine cytidylyltransferase to the endoplasmic reticulum and stimulate rat hepatic phosphatidylcholine synthesis.

    S L Pelech;P H Pritchard;D N Brindley;D E Vance

  • Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK.

    Atsushi Nakano;Christopher P. Baines;Sung O. Kim;Steven L. Pelech

  • Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts.

    J Posada;J Sanghera;S Pelech;R Aebersold

  • Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord

    J.-H. Hu;H. Zhang;R. Wagey;C. Krieger;C. Krieger

  • p42 mitogen-activated protein kinase in brain: Prominent localization in neuronal cell bodies and dendrites

    R. S. Fiore;V. E. Bayer;S. L. Pelech;J. Posada

  • Chemotactic Peptide N-formyl-Met-Leu-Phe Activation of p38 Mitogen-activated Protein Kinase (MAPK) and MAPK-activated Protein Kinase-2 in Human Neutrophils

    Eric Krump;Jasbinder S. Sanghera;Steven L. Pelech;Wendy Furuya

  • Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions (synaptic transmissionysynaptic plasticityysynaptic vesicle proteinsysignal transductionysynaptogenesis)

    Jasmina N. Jovanovic;Fabio Benfenati;Aw L. Siow;S. Sihra

Frequent Co-Authors

Dennis E. Vance
Dennis E. Vance University of Alberta
Vincent Duronio
Vincent Duronio University of British Columbia
John H. McNeill
John H. McNeill University of British Columbia
Helen M. Burt
Helen M. Burt University of British Columbia
Veli-Jukka Uitto
Veli-Jukka Uitto University of Helsinki
Seung U. Kim
Seung U. Kim University of British Columbia
Nelly Auersperg
Nelly Auersperg University of British Columbia
Ian Clark-Lewis
Ian Clark-Lewis University of British Columbia
Catharine H. Rankin
Catharine H. Rankin University of British Columbia
Ruth A. Lanius
Ruth A. Lanius University of Western Ontario

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