Els Pardon

Overview

Best Publications

• Crystal structure of the β2 adrenergic receptor-Gs protein complex.

  Søren G. F. Rasmussen;Brian T. DeVree;Yaozhong Zou;Andrew C. Kruse

  3614
  Citations

• Structure of a nanobody-stabilized active state of the β2 adrenoceptor

  Søren G F Rasmussen;Hee Jung Choi;Juan Jose Fung;Els Pardon

  2050
  Citations

• Activation and allosteric modulation of a muscarinic acetylcholine receptor

  Andrew C. Kruse;Aaron M. Ring;Aashish Manglik;Jianxin Hu

  1015
  Citations

• A general protocol for the generation of Nanobodies for structural biology

  Els Pardon;Toon Laeremans;Sarah Triest;Søren G F Rasmussen

  868
  Citations

• Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13, in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome)

  Gert Matthijs;E Schollen;Els Pardon;M Veiga-Da-Cunha

  403
  Citations

• GABAAreceptor signalling mechanisms revealed by structural pharmacology.

  S. Masiulis;R. Desai;T. Uchanski;I. Serna Martin

  401
  Citations

• Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

  Tao Che;Susruta Majumdar;Saheem A. Zaidi;Pauline Ondachi

  374
  Citations

• Cryo-EM structure of the human α1β3γ2 GABA A receptor in a lipid bilayer.

  Laverty D;Desai R;Uchański T;Masiulis S

  342
  Citations

• Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

  Dean P Staus;Ryan T Strachan;Aashish Manglik;Biswaranjan Pani

  323
  Citations

• Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

  Brian T. Devree;Jacob P. Mahoney;Gisselle A. Vélez-Ruiz;Soren G.F. Rasmussen

  283
  Citations

• Structural insights into the activation of metabotropic glutamate receptors.

  Antoine Koehl;Hongli Hu;Dan Feng;Bingfa Sun

  283
  Citations

• Structural flexibility of the Gαs α-helical domain in the β 2-adrenoceptor Gs complex

  Gerwin H. Westfield;Søren G. F. Rasmussen;Søren G. F. Rasmussen;Min Su;Somnath Dutta

  283
  Citations

• Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies.

  Dirk Saerens;Mireille Pellis;Remy Loris;Els Pardon

  277
  Citations

• Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.

  Andrew A.B. Ward;Paul Szewczyk;Vinciane Grimard;Chang-Wook Lee

  274
  Citations

• The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier

  Jonathan J Ruprecht;Martin S King;Thomas Zögg;Antoniya A Aleksandrova

  255
  Citations

• Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes

  Ksenia Rostislavleva;Nicolas Soler;Yohei Ohashi;Lufei Zhang

  243
  Citations

• Crystal Structure of the N-Terminal Domain of the Secretin GspD from ETEC Determined with the Assistance of a Nanobody

  Konstantin V. Korotkov;Els Pardon;Jan Steyaert;Wim G.J. Hol

  218
  Citations

• Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.

  Ines A Ehrnstorfer;Eric R Geertsma;Eric R Geertsma;Els Pardon;Jan Steyaert;Jan Steyaert

  211
  Citations

• Structure and Properties of a Complex of alpha-Synuclein and a Single-Domain Camelid Antibody

  Erwin J De Genst;Tim Guilliams;Joke Wellens;Elizabeth M O'Day

  207
  Citations

• Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.

  Eric R Geertsma;Eric R Geertsma;Yung-Ning Chang;Yung-Ning Chang;Farooque R Shaik;Yvonne Neldner

  191
  Citations