World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
11750
World Ranking
15535
National Ranking
1223

Overview

A. Radu Aricescu is a researcher affiliated with the MRC Laboratory of Molecular Biology in the United Kingdom. Their academic focus is situated within the field of Biochemistry, Genetics, and Molecular Biology, with significant contributions particularly in Molecular Biology, Structural Biology, Cellular and Molecular Neuroscience, Radiology, Nuclear Medicine and Imaging, and Biophysics.

Their research encompasses a range of topics, including:

  • Advanced Electron Microscopy Techniques and Applications
  • Neuroscience and Neuropharmacology Research
  • Enzyme Structure and Function
  • Force Microscopy Techniques and Applications
  • Advanced Fluorescence Microscopy Techniques
  • X-ray Spectroscopy and Fluorescence Analysis
  • RNA and protein synthesis mechanisms

Among their recent published papers, notable titles are:

  • Single-particle cryo-EM at atomic resolution, 2020, Nature
  • Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM, 2021, Nature Methods
  • A synthetic synaptic organizer protein restores glutamatergic neuronal circuits, 2020, Science
  • Differential assembly diversifies GABAA receptor structures and signalling, 2022, Nature
  • Single-particle cryo-EM at atomic resolution, 2020, bioRxiv (Cold Spring Harbor Laboratory)

They have frequently published in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Nature
  • Nature Methods
  • Nature Biotechnology

Throughout their career, this scientist has collaborated regularly with a number of coauthors, including Tomas Malinauskas, Abhay Kotecha, Andrija Sente, Dimple Karia, and Veronica T. Chang.

Best Publications

  • A time- and cost-efficient system for high-level protein production in mammalian cells.

    A.R. Aricescu;W. Lu;E.Y. Jones

  • Crystal structure of a human GABAA receptor

    Paul S. Miller;A. Radu Aricescu

  • Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    Jenny C. Taylor;Jenny C. Taylor;Hilary C. Martin;Stefano Lise;John Broxholme

  • Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension

    Charlotte H. Coles;Yingjie Shen;Alan P. Tenney;Alan P. Tenney;Christian Siebold

  • Glycoprotein Structural Genomics: Solving the Glycosylation Problem

    V T Chang;M Crispin;M Crispin;A R Aricescu;D J Harvey

  • Cryo-EM structure of the human α1β3γ2 GABA A receptor in a lipid bilayer.

    Laverty D;Desai R;Uchański T;Masiulis S

  • Initiation of T cell signaling by CD45 segregation at 'close contacts'

    Veronica T Chang;Ricardo A Fernandes;Kristina A Ganzinger;Steven F Lee

  • Heparan Sulfate Proteoglycans Are Ligands for Receptor Protein Tyrosine Phosphatase σ

    A. Radu Aricescu;Iain W. McKinnell;Willi Halfter;Andrew W. Stoker

  • An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly

    E Seiradake;K Harlos;G Sutton;A.R Aricescu

  • Atomic-resolution monitoring of protein maturation in live human cells by NMR

    Lucia Banci;Letizia Barbieri;Ivano Bertini;Enrico Luchinat

  • Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2

    T.A Bowden;A.R Aricescu;R.J Gilbert;J.M Grimes

  • Anterograde C1ql1 Signaling Is Required in Order to Determine and Maintain a Single-Winner Climbing Fiber in the Mouse Cerebellum

    Wataru Kakegawa;Nikolaos Mitakidis;Eriko Miura;Manabu Abe

  • Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins

    Keiko Matsuda;Timotheus Budisantoso;Nikolaos Mitakidis;Yuki Sugaya

  • Protein tyrosine phosphatases: structure-function relationships

    Lydia Tabernero;A. Radu Aricescu;E. Yvonne Jones;Stefan E. Szedlacsek

  • Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships.

    Peng Zhang;Hong Lu;Rui T. Peixoto;Rui T. Peixoto;Mary K. Pines

  • Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1

    T Malinauskas;A R Aricescu;W Lu;C Siebold

  • Structural basis for GABAA receptor potentiation by neurosteroids.

    Paul S Miller;Suzanne Scott;Suzanne Scott;Simonas Masiulis;Simonas Masiulis;Luigi De Colibus

  • Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins.

    J Elegheert;E Behiels;E Behiels;E Behiels;B Bishop;S Scott;S Scott

  • Immunoglobulin superfamily cell adhesion molecules: zippers and signals.

    A Radu Aricescu;E Yvonne Jones

  • Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.

    B Bishop;A R Aricescu;K Harlos;C A O'Callaghan

Frequent Co-Authors

Christian Siebold
Christian Siebold University of Oxford
Michisuke Yuzaki
Michisuke Yuzaki Keio University
Simon J. Davis
Simon J. Davis University of Oxford
Simon Myers
Simon Myers Queen Mary University of London
David I. Stuart
David I. Stuart University of Oxford
Masahiko Watanabe
Masahiko Watanabe Hokkaido University
Alexander Dityatev
Alexander Dityatev German Center for Neurodegenerative Diseases
Els Pardon
Els Pardon Vrije Universiteit Brussel
Max Crispin
Max Crispin University of Southampton
Anja Kipar
Anja Kipar University of Zurich

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