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Christian Siebold

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
9623
World Ranking
16211
National Ranking
1280

Christian Siebold publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Christian Siebold sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 198 publications — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Christian Siebold D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Christian Siebold sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 53 D-Index — 19th percentile

19% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Christian Siebold is affiliated with the University of Oxford in the United Kingdom and has contributed extensively to research in biochemistry, genetics, and molecular biology. Their primary fields of study include molecular biology, genetics, atomic and molecular physics and optics, cell biology, and oncology.

The scientist's recent research covers a range of topics related to cellular signaling pathways, lipid membrane structure, genomics, and protein dynamics. Key topics include Hedgehog signaling pathway studies, genomics and chromatin dynamics, lipid membrane structure and behavior, epigenetics and DNA methylation, protein structure and dynamics, spectroscopy and quantum chemical studies, as well as Wnt/β-catenin signaling in development and cancer.

Their publication record includes work in a variety of scientific journals and platforms. Frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Biophysical Journal
  • eLife
  • Nature Communications

Significant recent papers by Christian Siebold include:

  • "Cholesterol access in cellular membranes controls Hedgehog signaling", 2020, Nature Chemical Biology
  • "Glypicans shield the Wnt lipid moiety to enable signalling at a distance", 2020, Nature
  • "R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling", 2020, eLife
  • "Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes", 2021, eLife
  • "Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain", 2022, Science Advances

The scientist collaborates with several frequent co-authors, including T. Bertie Ansell, Mark S.P. Sansom, Rajat Rohatgi, Claire E. Coupland, and Maia Kinnebrew.

Best Publications

  • MHC class II proteins and disease: a structural perspective

    E Y Jones;L Fugger;L Fugger;J L Strominger;C Siebold

  • Mutations in α-Tubulin Cause Abnormal Neuronal Migration in Mice and Lissencephaly in Humans

    David A. Keays;Guoling Tian;Karine Poirier;Guo Jen Huang

  • Structural basis of Smoothened regulation by its extracellular domains

    Eamon F. X. Byrne;Ria Sircar;Paul S. Miller;George Hedger

  • Proteoglycan-Specific Molecular Switch for RPTPσ Clustering and Neuronal Extension

    Charlotte H. Coles;Yingjie Shen;Alan P. Tenney;Alan P. Tenney;Christian Siebold

  • Initiation of T cell signaling by CD45 segregation at 'close contacts'

    Veronica T Chang;Ricardo A Fernandes;Kristina A Ganzinger;Steven F Lee

  • A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization.

    T.S. Walter;J.M. Diprose;C.J. Mayo;C. Siebold

  • Structural basis of semaphorin–plexin signalling

    Bert J. C. Janssen;Ross A. Robinson;Francesc Pérez-Brangulí;Christian H. Bell

  • Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A).

    Karine Poirier;Karine Poirier;David A. Keays;Fiona Francis;Fiona Francis;Yoann Saillour;Yoann Saillour

  • Interactions between Hedgehog proteins and their binding partners come into view.

    Philip A. Beachy;Sarah G. Hymowitz;Robert A. Lazarus;Daniel J. Leahy

  • Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling.

    Giovanni Luchetti;Ria Sircar;Jennifer H Kong;Sigrid Nachtergaele

  • Biochemical mechanisms of vertebrate hedgehog signaling.

    Jennifer H. Kong;Christian Siebold;Rajat Rohatgi

  • Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

    Janssen Bjc.;T Malinauskas;G A Weir;M Z Cader

  • Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.

    J. Brown;C.A. O'Callaghan;A.S.J. Marshall;R.J.C. Gilbert

  • Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy

    Christian Siebold;Bjarke E. Hansen;Jessica R. Wyer;Karl Harlos

  • Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.

    M Lu;H Breyssens;V Salter;S Zhong

  • Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling

    Sigrid Nachtergaele;Daniel M Whalen;Laurel K Mydock;Zhonghua Zhao

  • Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1

    T Malinauskas;A R Aricescu;W Lu;C Siebold

  • Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins.

    J Elegheert;E Behiels;E Behiels;E Behiels;B Bishop;S Scott;S Scott

  • Carbohydrate transporters of the bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS)

    Christian Siebold;Karin Flükiger;Rudolf Beutler;Bernhard Erni

  • Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.

    B Bishop;A R Aricescu;K Harlos;C A O'Callaghan

Frequent Co-Authors

E Y Jones
E Y Jones University of Oxford
Robert J. C. Gilbert
Robert J. C. Gilbert University of Oxford
Douglas F. Covey
Douglas F. Covey Washington University in St. Louis
Mark S.P. Sansom
Mark S.P. Sansom University of Oxford
A. Radu Aricescu
A. Radu Aricescu MRC Laboratory of Molecular Biology
David I. Stuart
David I. Stuart University of Oxford
Karl Harlos
Karl Harlos University of Oxford
Jan Steyaert
Jan Steyaert Vrije Universiteit Brussel
Els Pardon
Els Pardon Vrije Universiteit Brussel
R. Jeroen Pasterkamp
R. Jeroen Pasterkamp Utrecht University

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Best Scientists Citing Christian Siebold

David I. Stuart

David I. Stuart

University of Oxford

Publications: 84

Raymond J. Owens

Raymond J. Owens

University of Oxford

Publications: 61

Jingshan Ren

Jingshan Ren

University of Oxford

Publications: 53

Karl Harlos

Karl Harlos

University of Oxford

Publications: 46

Jonathan M. Grimes

Jonathan M. Grimes

University of Oxford

Publications: 44

Fiona Francis

Fiona Francis

Inserm

Publications: 40

Jamel Chelly

Jamel Chelly

Institute of Genetics and Molecular and Cellular Biology

Publications: 37

Simon J. Davis

Simon J. Davis

University of Oxford

Publications: 32

E Y Jones

E Y Jones

University of Oxford

Publications: 31

Elizabeth E. Fry

Elizabeth E. Fry

University of Oxford

Publications: 27

William B. Dobyns

William B. Dobyns

University of Minnesota

Publications: 25

A. Radu Aricescu

A. Radu Aricescu

MRC Laboratory of Molecular Biology

Publications: 25

Michael L. Dustin

Michael L. Dustin

University of Oxford

Publications: 25

Jamie Rossjohn

Jamie Rossjohn

Monash University

Publications: 20

Juthathip Mongkolsapaya

Juthathip Mongkolsapaya

University of Oxford

Publications: 18

William J. Griffiths

William J. Griffiths

Swansea University

Publications: 17

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