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William J. Griffiths

William J. Griffiths

D-Index & Metrics

Chemistry

D-Index
69
Citations
16391
World Ranking
6212
National Ranking
358

Research.com Recognitions

  • 1962 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

William J. Griffiths is affiliated with Swansea University in the United Kingdom. Their primary fields of study encompass Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology and Surgery as key subfields.

Their research extensively covers topics related to Cholesterol and Lipid Metabolism, Metabolomics and Mass Spectrometry Studies, Drug Transport and Resistance Mechanisms, Advanced Proteomics Techniques and Applications, Mass Spectrometry Techniques and Applications, Peroxisome Proliferator-Activated Receptors, and Alzheimer's disease research and treatments.

Among recent papers authored or co-authored by Griffiths are the following:

  • Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures (2020), Journal of Lipid Research
  • Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion (2020), Proceedings of the National Academy of Sciences
  • Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease (2020), Cell Reports Medicine
  • LIPID MAPS: update to databases and tools for the lipidomics community (2023), Nucleic Acids Research
  • The Biosynthesis of Enzymatically Oxidized Lipids (2020), Frontiers in Endocrinology

Frequent co-authors include Yuqin Wang, Eylan Yutuc, Valerie B. O'Donnell, Alison L. Dickson, and Harald Köfeler.

Griffiths has published multiples works in various scientific venues. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Lipid Research
  • Journal of Hepatology
  • Proceedings of the National Academy of Sciences
  • Frontiers in Endocrinology

In addition to journal articles, Griffiths has contributed to book literature with a publication titled "Lipidomics" (2020) under the Royal Society of Chemistry.

The scientist was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 1962.

Best Publications

  • Docosahexaenoic Acid, a Ligand for the Retinoid X Receptor in Mouse Brain

    Alexander Mata de Urquiza;Suya Liu;Maria Sjöberg;Rolf H. Zetterström

  • Shorthand notation for lipid structures derived from mass spectrometry

    Gerhard Liebisch;Juan Antonio Vizcaíno;Harald Köfeler;Martin Trötzmüller

  • Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures

    Gerhard Liebisch;Eoin Fahy;Junken Aoki;Edward A. Dennis

  • Targeted Metabolomics for Biomarker Discovery

    William J. Griffiths;Therese Koal;Yuqin Wang;Matthias Kohl

  • The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

    Mathieu Blanc;Wei Yuan Hsieh;Kevin A. Robertson;Kai A. Kropp

  • Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain.

    Johan Lengqvist;Johan Lengqvist;Alexander Mata de Urquiza;Ann Charlotte Bergman;Timothy M. Willson

  • Mass spectrometry: from proteomics to metabolomics and lipidomics

    William J. Griffiths;Yuqin Wang

  • Tandem mass spectrometry in the study of fatty acids, bile acids, and steroids.

    William J. Griffiths

  • Electrospray and tandem mass spectrometry in biochemistry.

    William J. Griffiths;Andreas P. Jonsson;Suya Liu;Dilip K. Rai

  • Bile acids: analysis in biological fluids and tissues.

    William J. Griffiths;Jan Sjövall

  • Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion.

    Ruochen Zang;Ruochen Zang;James Brett Case;Eylan Yutuc;Xiucui Ma;Xiucui Ma

  • DMSO-Related Effects in Protein Characterization

    Agneta Tjernberg;Natalia Markova;William J. Griffiths;Dan Hallén

  • Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells

    Stina Feltenmark;Narinder Gautam;Åsa Brunnström;William Griffiths

  • Release of metabolic enzymes by Giardia in response to interaction with intestinal epithelial cells.

    Emma Ringqvist;J.E. Daniel Palm;J.E. Daniel Palm;Hanna Skarin;Adrian B. Hehl

  • Lipidomics needs more standardization

    Gerhard Liebisch;Robert Ahrends;Robert Ahrends;Arita Makoto;Arita Masanori

  • Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer’s Disease

    Priyanka Baloni;Cory C Funk;Jingwen Yan;James T Yurkovich

  • Derivatisation for the characterisation of neutral oxosteroids by electrospray and matrix‐assisted laser desorption/ionisation tandem mass spectrometry: the Girard P derivative

    William J. Griffiths;Suya Liu;Gunvor Alvelius;Jan Sjövall

  • Identification of immunoreactive proteins during acute human giardiasis.

    J. E. Daniel Palm;Malin E.-L Weiland;William J Griffiths;Inger Ljungström

  • Neurosteroids in Rat Brain: Extraction, Isolation, and Analysis by Nanoscale Liquid Chromatography−Electrospray Mass Spectrometry

    Suya Liu;Jan Sjövall;William J. Griffiths

  • The Biosynthesis of Enzymatically Oxidized Lipids.

    Ali A Hajeyah;William J Griffiths;Yuqin Wang;Andrew J Finch

  • Vernix caseosa as a multi-component defence system based on polypeptides, lipids and their interactions

    Maria Tollin;Gudmundur Bergsson;Ylva Kai-Larsen;Johan Lengqvist

Frequent Co-Authors

Jan Sjövall
Jan Sjövall Karolinska Institute
Tomas Bergman
Tomas Bergman Karolinska Institute
Ingemar Björkhem
Ingemar Björkhem Karolinska University Hospital
Jan Johansson
Jan Johansson Karolinska Institute
Hans Jörnvall
Hans Jörnvall Karolinska Institute
Ernest Arenas
Ernest Arenas Karolinska Institute
Peter E. Clayton
Peter E. Clayton University of Manchester
Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
Birgitta Agerberth
Birgitta Agerberth Karolinska Institute
Ludger Schöls
Ludger Schöls University of Tübingen

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