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Chemistry

D-Index
67
Citations
14958
World Ranking
6954
National Ranking
2073

Overview

Keith W. Miller is affiliated with Harvard University in the United States. Their research primarily focuses on the fields of neuroscience and biochemistry, genetics, and molecular biology. Within these broader areas, their work often addresses subfields including cellular and molecular neuroscience, molecular biology, neurology, radiology, nuclear medicine and imaging, and spectroscopy.

The scientist's research topics center on neuroscience and neuropharmacology, receptor mechanisms and signaling, nicotinic acetylcholine receptor studies, neuroinflammation and neurodegeneration mechanisms, molecular sensors and ion detection, photochromic and fluorescence chemistry, as well as advanced radiotherapy techniques.

Keith W. Miller has contributed to several recent papers, including:

  • Differential assembly diversifies GABAA receptor structures and signalling, 2022, Nature
  • Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors, 2020, Journal of Biological Chemistry
  • Competitive Antagonism of Etomidate Action by Diazepam, 2020, Anesthesiology
  • A potent photoreactive general anesthetic with novel binding site selectivity for GABAA receptors, 2020, European Journal of Medicinal Chemistry
  • An In Silico study of a One-Day One-Machine Workflow for Definitive Radiotherapy Cases on a Novel Simulation and Treatment Platform, 2023, International Journal of Radiation Oncology*Biology*Physics

Frequent coauthors collaborating with Miller include Xiaojuan Zhou, Karol S. Bruzik, Jonathan B. Cohen, Dimosthenis Koinas, and Youssef Jounaïdi.

Their research has been published in venues such as:

  • Journal of Biological Chemistry
  • Nature
  • Anesthesiology
  • International Journal of Radiation Oncology*Biology*Physics
  • Journal of Medicinal Chemistry

Best Publications

  • Processing of tumour necrosis factor-alpha precursor by metalloproteinases

    A. J. H. Gearing;P. Beckett;M. Christodoulou;M. Churchill

  • GABAAreceptor signalling mechanisms revealed by structural pharmacology.

    S. Masiulis;R. Desai;T. Uchanski;I. Serna Martin

  • The Pressure Reversal of General Anesthesia and the Critical Volume Hypothesis

    K. W. Miller;W. D. M. Paton;R. A. Smith;E. B. Smith

  • Cryo-EM structure of the human α1β3γ2 GABA A receptor in a lipid bilayer.

    Laverty D;Desai R;Uchański T;Masiulis S

  • Increased mutability of Pseudomonas aeruginosa in biofilms

    K Driffield;Keith Miller;J M Bostock;A J O'Neill

  • Xenon NMR: Chemical shifts of a general anesthetic in common solvents, proteins, and membranes

    K W Miller;N V Reo;A J Schoot Uiterkamp;D P Stengle

  • The nature of the site of general anesthesia.

    Keith W. Miller

  • Can the lipid theories of anesthesia account for the cutoff in anesthetic potency in homologous series of alcohols

    Michael J. Pringle;Kenneth B. Brown;Keith W. Miller

  • Immunohistochemical detection of steroid receptors in breast cancer: a working protocol

    Robin Leake;Diana Barnes;Sarah Pinder;Ian Ellis

  • Anaesthetic potencies of primary alkanols: implications for the molecular dimensions of the anaesthetic site.

    James K. Alifimoff;Leonard L. Firestone;Keith W. Miller

  • Correlation of general anesthetic potency with solubility in membranes.

    Andrew S. Janoff;Michael J. Pringle;Keith W. Miller

  • A discrete site for general anesthetics on a postsynaptic receptor.

    S A Forman;K W Miller;G Yellen

  • Physicochemical Approaches to the Mode of Action of General Anesthetics

    K W Miller;W D M Paton;E B Smith;R A Smith

  • HER2 testing in the UK - further update to recommendations

    Rosemary A Walker;John Bartlett;Mitch Dowsett;Ian O Ellis

  • Molecular and Cellular Mechanisms of Anesthetics

    Sheldon H. Roth;Keith W. Miller

  • General anaesthetics can selectively perturb lipid bilayer membranes

    Keith W. Miller;Kam-Yee Y. Pang

  • Consequences of daptomycin-mediated membrane damage in Staphylococcus aureus

    Joanne Karen Hobbs;Keith Miller;Alex John O’Neill;Ian Chopra

  • The cholesterol dependence of activation and fast desensitization of the nicotinic acetylcholine receptor

    S.E. Rankin;G.H. Addona;M.A. Kloczewiak;B. Bugge

  • Specificity of Intersubunit General Anesthetic-binding Sites in the Transmembrane Domain of the Human α1β3γ2 γ-Aminobutyric Acid Type A (GABAA) Receptor

    David C. Chiara;Selwyn S. Jayakar;Xiaojuan Zhou;Xi Zhang

  • Cholesterol modulates the effects of membrane perturbers in phospholipid vesicles and biomembranes.

    Kam-Yee Y. Pang;Keith W. Miller

  • Methoxycarbonyl-etomidate: a novel rapidly metabolized and ultra-short-acting etomidate analogue that does not produce prolonged adrenocortical suppression.

    Joseph F Cotten;S Shaukat Husain;Stuart A Forman;Keith W Miller

Frequent Co-Authors

Jonathan B. Cohen
Jonathan B. Cohen Harvard University
Ian Chopra
Ian Chopra University of Leeds
Alex J. O'Neill
Alex J. O'Neill University of Leeds
Jan Steyaert
Jan Steyaert Vrije Universiteit Brussel
Els Pardon
Els Pardon Vrije Universiteit Brussel
Anthony Watts
Anthony Watts University of Oxford
Clive R. Taylor
Clive R. Taylor University of Southern California
Richard W. Olsen
Richard W. Olsen University of California, Los Angeles
Paul E. Swanson
Paul E. Swanson University of Washington
Ian O. Ellis
Ian O. Ellis University of Nottingham

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