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Microbiology

D-Index
60
Citations
20430
World Ranking
3063
National Ranking
51

Overview

Oana Ciofu is affiliated with the University of Copenhagen in Denmark and focuses their research on microbial biofilms, antibiotic resistance, and molecular biology within the broader fields of biochemistry, genetics, and molecular biology. Their work intersects with subfields such as molecular medicine, endocrinology, microbiology, and environmental pollution, reflecting a multidisciplinary approach to studying bacterial behavior and resistance mechanisms.

Their research frequently addresses topics including:

  • Bacterial biofilms and quorum sensing
  • Antibiotic resistance in bacteria
  • Antimicrobial peptides and activities
  • Pharmaceutical and antibiotic environmental impacts
  • Inhalation and respiratory drug delivery
  • Bacteriophages and microbial interactions
  • Infections and bacterial resistance

Oana Ciofu's publication record includes significant contributions to peer-reviewed journals, with recent papers such as:

  • "Tolerance and resistance of microbial biofilms", 2022, Nature Reviews Microbiology
  • "The evolutionary trajectories of P. aeruginosa in biofilm and planktonic growth modes exposed to ciprofloxacin: beyond selection of antibiotic resistance", 2020, npj Biofilms and Microbiomes
  • "In vivo evolution of antimicrobial resistance in a biofilm model of Pseudomonas aeruginosa lung infection", 2024, The ISME Journal
  • "Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs", 2022, Nature Ecology & Evolution
  • "Colistin Enhances Rifampicin's Antimicrobial Action in Colistin-Resistant Pseudomonas aeruginosa Biofilms", 2023, Antimicrobial Agents and Chemotherapy

Oana Ciofu frequently collaborates with coauthors including:

  • Niels Høiby
  • Claus Moser
  • Doaa Higazy
  • Anan Yaghmur
  • Kim Thomsen

Their publications appear regularly in journals such as:

  • Journal of Colloid and Interface Science
  • Apmis
  • npj Biofilms and Microbiomes
  • Antimicrobial Agents and Chemotherapy
  • Microorganisms

Best Publications

  • Antibiotic resistance of bacterial biofilms

    Niels Høiby;Thomas Bjarnsholt;Michael Givskov;Søren Molin

  • Tolerance and resistance of microbial biofilms

    Unknown

  • The clinical impact of bacterial biofilms

    Niels Høiby;Oana Ciofu;Helle Krogh Johansen;Zhi-jun Song

  • Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

    Anders Folkesson;Lars Jelsbak;Lei Yang;Lei Yang;Helle Krogh Johansen

  • Pseudomonas aeruginosa biofilms in cystic fibrosis

    Niels Høiby;Oana Ciofu;Thomas Bjarnsholt

  • Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents-How P. aeruginosa Can Escape Antibiotics

    Oana Ciofu;Tim Tolker-Nielsen

  • Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

    Kalai Mathee;Oana Ciofu;Claus Sternberg;Peter W. Lindum

  • Applying insights from biofilm biology to drug development — can a new approach be developed?

    Thomas Bjarnsholt;Oana Ciofu;Søren Molin;Michael Givskov;Michael Givskov

  • Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.

    Niels Høiby;Helle Krogh Johansen;Claus Moser;Zhijun Song

  • Antibiotic treatment of biofilm infections.

    Oana Ciofu;Estrella Rojo-Molinero;María D. Macià;Antonio Oliver

  • Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production

    Niels Bagge;Martin Schuster;Morten Hentzer;Oana Ciofu

  • Evolutionary dynamics of bacteria in a human host environment

    Lei Yang;Lars Jelsbak;Rasmus Lykke Marvig;Søren Damkiær

  • Chromosomal beta-lactamase is packaged into membrane vesicles and secreted from Pseudomonas aeruginosa.

    Oana Ciofu;Terry J. Beveridge;Jagath Kadurugamuwa;Jan Walther-Rasmussen

  • Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients.

    Oana Ciofu;Tim Tolker-Nielsen;Peter Østrup Jensen;Hengzhuang Wang

  • Occurrence of Hypermutable Pseudomonas aeruginosa in Cystic Fibrosis Patients Is Associated with the Oxidative Stress Caused by Chronic Lung Inflammation

    Oana Ciofu;Bente Riis;Tacjana Pressler;Henrik Enghusen Poulsen

  • Molecular Mechanisms of Fluoroquinolone Resistance in Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients

    Shah Jalal;Oana Ciofu;Niels Høiby;Naomasa Gotoh

  • Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients.

    Thomas Bjarnsholt;Peter Østrup Jensen;Tim Holm Jakobsen;Richard Phipps

  • Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.

    Lars Jelsbak;Helle Krogh Johansen;Anne Louise Viborg Frost;Regitze Thøgersen

  • Genetic adaptation of Pseudomonas aeruginosa during chronic lung infection of patients with cystic fibrosis: strong and weak mutators with heterogeneous genetic backgrounds emerge in mucA and/or lasR mutants.

    Oana Ciofu;Lotte F. Mandsberg;Thomas Bjarnsholt;Tina Wassermann

  • Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

    Susse Kirkelund Hansen;Martin Holm Rau;Helle Krogh Johansen;Oana Ciofu

  • Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis

    Nadine Hoffmann;Thomas Bovbjerg Rasmussen;Peter Østrup Jensen;Charlotte Stub

Frequent Co-Authors

Niels Høiby
Niels Høiby University of Copenhagen
Thomas Bjarnsholt
Thomas Bjarnsholt University of Copenhagen
Peter Østrup Jensen
Peter Østrup Jensen University of Copenhagen
Helle Krogh Johansen
Helle Krogh Johansen University of Copenhagen
Søren Molin
Søren Molin Technical University of Denmark
Michael Givskov
Michael Givskov University of Copenhagen
Claus Moser
Claus Moser University of Copenhagen
Michael Kühl
Michael Kühl University of Copenhagen
Tim Tolker-Nielsen
Tim Tolker-Nielsen University of Copenhagen
Morten Otto Alexander Sommer
Morten Otto Alexander Sommer Technical University of Denmark

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