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Helle Krogh Johansen

Helle Krogh Johansen

D-Index & Metrics

Microbiology

D-Index
78
Citations
21284
World Ranking
1289
National Ranking
18

Overview

Helle Krogh Johansen is affiliated with the University of Copenhagen in Denmark. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a strong focus on Pulmonary and Respiratory Medicine, Molecular Biology, and Molecular Medicine. Additional areas include Endocrinology and Infectious Diseases.

Their work covers several main topics related to bacterial infections and respiratory health, such as Cystic Fibrosis Research Advances, Antibiotic Resistance in Bacteria, Bacterial biofilms and quorum sensing, Inhalation and Respiratory Drug Delivery, Infections and bacterial resistance, Bacteriophages and microbial interactions, and Genomics and Phylogenetic Studies.

Research publications are concentrated in a few key scientific journals, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Cystic Fibrosis
  • Nature Communications
  • Clinical Microbiology and Infection
  • Microbial Genomics

Frequent collaborators in their work include Søren Molin, Ruggero La Rosa, Rasmus L. Marvig, Tacjana Pressler, and Jennifer Bartell.

Selected recent publications illustrate the scope of their research contributions:

  • "Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis," 2020, Nature Reviews Microbiology
  • "Inter-species interactions alter antibiotic efficacy in bacterial communities," 2021, The ISME Journal
  • "Hypermutator Pseudomonas aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients," 2020, Antimicrobial Agents and Chemotherapy
  • "Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment," 2020, PLoS Pathogens
  • "Compensatory evolution of Pseudomonas aeruginosa's slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis," 2021, Nature Communications

Best Publications

  • The clinical impact of bacterial biofilms

    Niels Høiby;Oana Ciofu;Helle Krogh Johansen;Zhi-jun Song

  • Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

    Anders Folkesson;Lars Jelsbak;Lei Yang;Lei Yang;Helle Krogh Johansen

  • Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis

    Rasmus Lykke Marvig;Lea Mette Madsen Sommer;Søren Molin;Helle Krogh Johansen

  • Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB‐oprM genes

    Sünje Johanna Pamp;Morten Gjermansen;Helle Krogh Johansen;Tim Tolker-Nielsen

  • Biofilms in chronic infections – a matter of opportunity – monospecies biofilms in multispecies infections

    Mette Burmølle;Trine Rolighed Thomsen;Mustafa Fazli;Irene Dige

  • Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.

    Niels Høiby;Helle Krogh Johansen;Claus Moser;Zhijun Song

  • Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis.

    Elio Rossi;Ruggero La Rosa;Jennifer A. Bartell;Rasmus L. Marvig

  • House dust mite control measures for asthma.

    Peter C Gøtzsche;Helle Krogh Johansen

  • Evolutionary dynamics of bacteria in a human host environment

    Lei Yang;Lars Jelsbak;Rasmus Lykke Marvig;Søren Damkiær

  • Ghost Authorship in Industry-Initiated Randomised Trials

    Peter C Gøtzsche;Asbjørn Hróbjartsson;Helle Krogh Johansen;Mette T Haahr

  • Azithromycin Blocks Quorum Sensing and Alginate Polymer Formation and Increases the Sensitivity to Serum and Stationary-Growth-Phase Killing of Pseudomonas aeruginosa and Attenuates Chronic P. aeruginosa Lung Infection in Cftr−/− Mice

    Nadine Hoffmann;Baoleri Lee;Morten Hentzer;Thomas Bovbjerg Rasmussen

  • National Surveillance of Fungemia in Denmark (2004 to 2009)

    Maiken Cavling Arendrup;Brita Grønbech Bruun;Jens Jørgen Christensen;Kurt Fuursted

  • Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.

    Lars Jelsbak;Helle Krogh Johansen;Anne Louise Viborg Frost;Regitze Thøgersen

  • Environmental Study of Azole-Resistant Aspergillus fumigatus and Other Aspergilli in Austria, Denmark, and Spain

    Klaus Leth Mortensen;Emilia Mellado;Cornelia Lass-Flörl;Juan Luis Rodriguez-Tudela

  • PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients

    Samuel M. Moskowitz;Mark K. Brannon;Nandini Dasgupta;Miyuki Pier

  • In Situ Growth Rates and Biofilm Development of Pseudomonas aeruginosa Populations in Chronic Lung Infections

    Lei Yang;Janus Anders Juul Haagensen;Lars Jelsbak;Helle Krogh Johansen

  • PhoQ Mutations Promote Lipid A Modification and Polymyxin Resistance of Pseudomonas aeruginosa Found in Colistin-Treated Cystic Fibrosis Patients

    Amanda K. Miller;Mark K. Brannon;Laurel Stevens;Laurel Stevens;Helle Krogh Johansen

  • Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

    Susse Kirkelund Hansen;Martin Holm Rau;Helle Krogh Johansen;Oana Ciofu

  • Epidemiological changes with potential implication for antifungal prescription recommendations for fungaemia: data from a nationwide fungaemia surveillance programme

    M C Arendrup;Esad Dzajic;R H Jensen;H K Johansen

  • Genome analysis of a transmissible lineage of pseudomonas aeruginosa reveals pathoadaptive mutations and distinct evolutionary paths of hypermutators.

    Rasmus Lykke Marvig;Helle Krogh Johansen;Søren Molin;Lars Jelsbak

  • Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis

    Nadine Hoffmann;Thomas Bovbjerg Rasmussen;Peter Østrup Jensen;Charlotte Stub

Frequent Co-Authors

Niels Høiby
Niels Høiby University of Copenhagen
Søren Molin
Søren Molin Technical University of Denmark
Maiken Cavling Arendrup
Maiken Cavling Arendrup Statens Serum Institut
Oana Ciofu
Oana Ciofu University of Copenhagen
Thomas Bjarnsholt
Thomas Bjarnsholt University of Copenhagen
Claus Moser
Claus Moser University of Copenhagen
Michael Givskov
Michael Givskov University of Copenhagen
Peter Østrup Jensen
Peter Østrup Jensen University of Copenhagen
Anja Boisen
Anja Boisen Technical University of Denmark

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