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Gebhard F. X. Schertler

Gebhard F. X. Schertler

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
22283
World Ranking
10544
National Ranking
187

Overview

Gebhard F. X. Schertler is affiliated with the Paul Scherrer Institute in Switzerland. The scientist's research spans multiple areas within biochemistry, genetics, and molecular biology, with a significant focus also on neuroscience. Their work contributes to both fundamental and applied scientific understanding in these fields.

The primary fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

More specific subfields of study encompass:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Radiology, Nuclear Medicine and Imaging
  • Infectious Diseases
  • Spectroscopy

The research topics addressed in their publications mainly focus on:

  • Photoreceptor and optogenetics research
  • Receptor Mechanisms and Signaling
  • Retinal Development and Disorders
  • Neuroscience and Neuropharmacology Research
  • Monoclonal and Polyclonal Antibodies Research
  • Protein Structure and Dynamics
  • Enzyme Structure and Function

Among the frequent publication venues where this scientist's work has appeared are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Biophysical Journal
  • Journal of Structural Biology
  • Structural Dynamics

Frequent collaborators in their research include:

  • Ching-Ju Tsai
  • Xavier Deupí
  • Matthew J. Rodrigues
  • Jonas Mühle
  • Tobias Weinert

Notable recent publications by Gebhard F. X. Schertler include:

  • "Femtosecond-to-millisecond structural changes in a light-driven sodium pump" (2020, Nature)
  • "Ultrafast structural changes direct the first molecular events of vision" (2023, Nature)
  • "Dynamics and mechanism of a light-driven chloride pump" (2022, Science)
  • "Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist" (2021, Science Advances)
  • "Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large metropolitan region" (2020, bioRxiv (Cold Spring Harbor Laboratory))

Best Publications

  • Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.

    Søren G F Rasmussen;Hee Jung Choi;Daniel M. Rosenbaum;Tong Sun Kobilka

  • Structure of a beta1-adrenergic G-protein-coupled receptor.

    Tony Warne;Maria J. Serrano-Vega;Jillian G. Baker;Rouslan Moukhametzianov

  • Molecular signatures of G-protein-coupled receptors.

    A. J. Venkatakrishnan;Xavier Deupi;Guillaume Lebon;Christopher G. Tate

  • Projection structure of rhodopsin.

    Gebhard F. X. Schertler;Claudio Villa;Richard Henderson

  • Structure of bovine rhodopsin in a trigonal crystal form

    Jade Li;Patricia C. Edwards;Manfred Burghammer;Claudio Villa

  • AN ALPHA-CARBON TEMPLATE FOR THE TRANSMEMBRANE HELICES IN THE RHODOPSIN FAMILY OF G-PROTEIN COUPLED RECEPTORS

    Joyce M Baldwin;Gebhard F.X Schertler;Vinzenz M Unger

  • The structural basis for agonist and partial agonist action on a β(1)-adrenergic receptor.

    Tony Warne;Rouslan Moukhametzianov;Jillian G. Baker;Rony Nehmé

  • Arrangement of rhodopsin transmembrane α-helices

    Vinzenz M. Unger;Paul A. Hargrave;Joyce M. Baldwin;Gebhard F. X. Schertler

  • Structure of the µ-opioid receptor–G i protein complex

    Antoine Koehl;Hongli Hu;Shoji Maeda;Yan Zhang

  • The structural basis of agonist-induced activation in constitutively active rhodopsin

    Jörg Standfuss;Patricia C. Edwards;Aaron D’Antona;Maikel Fransen

  • A three-dimensional movie of structural changes in bacteriorhodopsin

    Eriko Nango;Antoine Royant;Antoine Royant;Minoru Kubo;Takanori Nakane

  • Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser

    Przemyslaw Nogly;Tobias Weinert;Daniel James;Sergio Carbajo

  • Electron crystallography reveals the structure of metarhodopsin I.

    Jonathan J Ruprecht;Thorsten Mielke;Reiner Vogel;Claudio Villa

  • Projection structure of frog rhodopsin in two crystal forms

    Gebhard F. X. Schertler;Paul A. Hargrave

  • Low resolution structure of bovine rhodopsin determined by electron cryo-microscopy

    V. M. Unger;G. F. X. Schertler

  • Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

    A. J. Venkatakrishnan;Xavier Deupi;Guillaume Lebon;Guillaume Lebon;Guillaume Lebon;Franziska M. Heydenreich;Franziska M. Heydenreich;Franziska M. Heydenreich

  • Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

    Xavier Deupi;Patricia Edwards;Ankita Singhal;Benjamin Nickle

  • Tracking G-protein-coupled receptor activation using genetically encoded infrared probes

    Shixin Ye;Ekaterina Zaitseva;Gianluigi Caltabiano;Gebhard F. X. Schertler;Gebhard F. X. Schertler

  • New G-protein-coupled receptor crystal structures: insights and limitations.

    Brian Kobilka;Gebhard F.X. Schertler

  • Crystal Structure of a Thermally Stable Rhodopsin Mutant.

    Jörg Standfuss;Guifu Xie;Patricia C. Edwards;Manfred Burghammer

Frequent Co-Authors

Christopher G. Tate
Christopher G. Tate MRC Laboratory of Molecular Biology
Dmitry B. Veprintsev
Dmitry B. Veprintsev University of Nottingham
Richard Neutze
Richard Neutze University of Gothenburg
Michel O. Steinmetz
Michel O. Steinmetz Paul Scherrer Institute
Manfred Burghammer
Manfred Burghammer European Synchrotron Radiation Facility
Hugues Matile
Hugues Matile Roche (Switzerland)
Brian K. Kobilka
Brian K. Kobilka Stanford University
Anton Barty
Anton Barty Universität Hamburg
So Iwata
So Iwata Kyoto University
Paul A. Hargrave
Paul A. Hargrave University of Florida

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