2010 - Gregori Aminoff Prize, Royal Swedish Academy of Sciences for his seminal crystallographic studies of membrane proteins. Using state-of-the-art crystallographic methods, he has elucidated vital biological functions within the fields of cellular respiration, photosynthesis and molecular transport
His primary scientific interests are in Protein structure, Biochemistry, Stereochemistry, Crystallography and Transport protein. His study in Protein structure is interdisciplinary in nature, drawing from both Oxidoreductase, Membrane transport protein, Membrane protein, Transmembrane domain and Cytochrome. His Stereochemistry study combines topics in areas such as Membrane transport, Proteolytic enzymes, Ion transporter, Escherichia coli and Lactose permease.
His Crystallography study incorporates themes from Structural biology, Photosystem II and Femtosecond. His research integrates issues of Conformational change, Thermus thermophilus and Electrochemical gradient in his study of Transport protein. His biological study spans a wide range of topics, including Ubiquinol oxidase and Quinone binding.
Biochemistry, Crystallography, Stereochemistry, Biophysics and Protein structure are his primary areas of study. His Crystallography research incorporates elements of X-ray crystallography, Crystallization and Femtosecond. As a part of the same scientific study, So Iwata usually deals with the Stereochemistry, concentrating on Membrane transport protein and frequently concerns with Membrane transport.
His work carried out in the field of Biophysics brings together such families of science as Membrane, G protein-coupled receptor, Crystal structure and Thermus thermophilus. So Iwata has researched Protein structure in several fields, including Plasma protein binding and Binding site. His Membrane protein research incorporates themes from Structural biology and Cell biology.
So Iwata spends much of his time researching Biophysics, Femtosecond, Receptor, G protein-coupled receptor and Crystallography. The Femtosecond study combines topics in areas such as Structural biology, Photochemistry, Retinal and Isomerization. His Receptor research is multidisciplinary, relying on both Pharmacology and Cell biology.
His studies deal with areas such as Muscarinic acetylcholine receptor, Ligand, Computational biology, Allosteric regulation and Binding site as well as G protein-coupled receptor. So Iwata does research in Crystallography, focusing on Protein crystallization specifically. He has included themes like Protein structure and Plasma protein binding in his Amino acid study.
His main research concerns Biophysics, Receptor, G protein-coupled receptor, Protein structure and Femtosecond. His Biophysics research is multidisciplinary, incorporating perspectives in Antiporters, Antiporter, Binding domain, Chromophore and Signal transduction. The study incorporates disciplines such as Docking, Serine and Binding site in addition to Receptor.
So Iwata focuses mostly in the field of G protein-coupled receptor, narrowing it down to topics relating to Allosteric regulation and, in certain cases, Angiotensin receptor, Angiotensin II and Lipid bilayer. While working on this project, So Iwata studies both Protein structure and Structure based. His Femtosecond research is multidisciplinary, incorporating elements of Crystallography, Structural biology and Photochemistry.
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Architecture of the Photosynthetic Oxygen-Evolving Center
Kristina N. Ferreira;Tina M. Iverson;Karim Maghlaoui;James Barber.
Science (2004)
Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans
So Iwata;Christian Ostermeier;Bernd Ludwig;Hartmut Michel.
Nature (1995)
Structure and mechanism of the lactose permease of Escherichia coli
Jeff Abramson;Irina Smirnova;Vladimir Kasho;Gillian Verner.
Science (2003)
Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
So Iwata;Joong W. Lee;Kengo Okada;Kengo Okada;John Kyongwon Lee.
Science (1998)
Architecture of succinate dehydrogenase and reactive oxygen species generation.
Victoria Yankovskaya;Rob Horsefield;Susanna Törnroth;César Luna-Chavez;César Luna-Chavez.
Science (2003)
Structure of the human histamine H1 receptor complex with doxepin.
Tatsuro Shimamura;Tatsuro Shimamura;Mitsunori Shiroishi;Mitsunori Shiroishi;Simone Weyand;Hirokazu Tsujimoto.
Nature (2011)
The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides.
Margareta Svensson-Ek;Jeff Abramson;Gisela Larsson;Gisela Larsson;Susanna Törnroth.
Journal of Molecular Biology (2002)
Overcoming the challenges of membrane protein crystallography.
Elisabeth P Carpenter;Konstantinos Beis;Alexander D Cameron;So Iwata;So Iwata.
Current Opinion in Structural Biology (2008)
Molecular basis of proton motive force generation: structure of formate dehydrogenase-N.
Mika Jormakka;Susanna Törnroth;Bernadette Byrne;So Iwata.
Science (2002)
The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding site.
Jeff Abramson;Sirpa Riistama;Gisela Larsson;Audrius Jasaitis.
Nature Structural & Molecular Biology (2000)
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