World's Best Scientists 2026 revealed!
Shigeyuki Yokoyama

Shigeyuki Yokoyama

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Molecular Biology

D-Index
138
Citations
69620
World Ranking
138
National Ranking
12

Biology and Biochemistry

D-Index
138
Citations
71680
World Ranking
301
National Ranking
10

Shigeyuki Yokoyama publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Shigeyuki Yokoyama sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 1,479 publications — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Shigeyuki Yokoyama D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Shigeyuki Yokoyama sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 138 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2011 - Fellow of the American Academy of Arts and Sciences

Overview

Shigeyuki Yokoyama is affiliated with RIKEN in Japan and has produced extensive research in the fields of biochemistry, genetics, and molecular biology, with additional contributions to medicine. Their work spans various subfields including molecular biology, genetics, epidemiology, immunology, and cell biology.

The primary topics Yokoyama has covered reflect a focus on molecular mechanisms and disease-related processes. These topics include:

  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Enzyme structure and function
  • Autophagy in disease and therapy
  • Endoplasmic reticulum stress and disease
  • Bacterial genetics and biotechnology
  • Heat shock proteins research

Yokoyama's recent publications illustrate a range of specific research interests. Notable papers include:

  • "Fully Productive Cell-Free Genetic Code Expansion by Structure-Based Engineering of Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase" (2020), published in ACS Synthetic Biology
  • "AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice" (2021), published in Communications Biology
  • "Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke" (2021), published in BMC Medicine
  • "Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method" (2020), published in Journal of Molecular Graphics and Modelling
  • "Human adiponectin receptor AdipoR1 assumes closed and open structures" (2020), published in Communications Biology

Frequent collaborators in Yokoyama's research include these coauthors:

  • Mikako Shirouzu (12 joint publications)
  • Kensaku Sakamoto (7 joint publications)
  • Akiko Tanaka (5 joint publications)
  • Kazue Terasawa (5 joint publications)
  • Tetsuro Watabe (5 joint publications)

The scientist often publishes in specialized journals such as:

  • Biochemical and Biophysical Research Communications (3 publications)
  • Biomolecular NMR Assignments (3 publications)
  • Communications Biology (2 publications)
  • ACS Synthetic Biology (1 publication)
  • BMC Medicine (1 publication)

In recognition of their contributions, Yokoyama was named a Fellow of the American Academy of Arts and Sciences in 2011.

Best Publications

  • Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains.

    Hideo Ogiso;Ryuichiro Ishitani;Osamu Nureki;Shuya Fukai

  • An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

    Antony W. Burgess;Hyun Soo Cho;Hyun Soo Cho;Charles Eigenbrot;Kathryn M. Ferguson

  • Protein production and purification.

    S Gräslund

  • Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution

    Dmitry G. Vassylyev;Shun-ichi Sekine;Oleg Laptenko;Jookyung Lee

  • Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer

    Balasundaram Padmanabhan;Kit I. Tong;Tsutomu Ohta;Yoshihiro Nakamura

  • Structural Basis for RNA Unwinding by the DEAD-Box Protein Drosophila Vasa

    Toru Sengoku;Osamu Nureki;Akira Nakamura;Satoru Kobayashi

  • Codon and amino-acid specificities of a transfer RNA are both converted by a single post-transcriptional modification.

    Tomonari Muramatsu;Kazuya Nishikawa;Fumiko Nemoto;Yoshiyuki Kuchino

  • CELL-FREE PRODUCTION AND STABLE-ISOTOPE LABELING OF MILLIGRAM QUANTITIES OF PROTEINS

    Takanori Kigawa;Takashi Yabuki;Yasuhiko Yoshida;Michio Tsutsui

  • Role of the ENTH Domain in Phosphatidylinositol-4,5-Bisphosphate Binding and Endocytosis

    Toshiki Itoh;Seizo Koshiba;Takanori Kigawa;Akira Kikuchi

  • An operational RNA code for amino acids and possible relationship to genetic code.

    Paul Schimmel;Richard Giege;Dino Moras;Shigeyuki Yokoyama

  • Generation of high-affinity DNA aptamers using an expanded genetic alphabet.

    Michiko Kimoto;Rie Yamashige;Ken-ichiro Matsunaga;Shigeyuki Yokoyama

  • Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein.

    Noriko Handa;Osamu Nureki;Kazuki Kurimoto;Insil Kim

  • Molecular computation by DNA hairpin formation.

    Kensaku Sakamoto;Hidetaka Gouzu;Ken Komiya;Daisuke Kiga

  • Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis

    Atsushi Shimada;Hideaki Niwa;Kazuya Tsujita;Shiro Suetsugu;Shiro Suetsugu

  • Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.

    Kit I. Tong;Balasundaram Padmanabhan;Akira Kobayashi;Chengwei Shang

  • Enzyme structure with two catalytic sites for double-sieve selection of substrate.

    Osamu Nureki;Dmitry G. Vassylyev;Masaru Tateno;Atsushi Shimada

  • Structural genomics projects in Japan.

    Shigeyuki Yokoyama;Hiroshi Hirota;Takanori Kigawa;Takashi Yabuki

  • Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

    Motoaki Wakiyama;Koji Takimoto;Osamu Ohara;Shigeyuki Yokoyama

  • Regulation through the Secondary Channel—Structural Framework for ppGpp-DksA Synergism during Transcription

    Anna Perederina;Vladimir Svetlov;Marina N Vassylyeva;Tahir H Tahirov

  • Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase

    Kliment A. Verba;Ray Yu-Ruei Wang;Akihiko Arakawa;Yanxin Liu

Frequent Co-Authors

Mikako Shirouzu
Mikako Shirouzu RIKEN Center for Biosystems Dynamics Research
Takaho Terada
Takaho Terada University of Tokyo
Takanori Kigawa
Takanori Kigawa RIKEN Center for Biosystems Dynamics Research
Seiki Kuramitsu
Seiki Kuramitsu Osaka University
Ichiro Hirao
Ichiro Hirao Xenolis Pte. Ltd.
Osamu Nureki
Osamu Nureki University of Tokyo
Tatsuo Miyazawa
Tatsuo Miyazawa University of Tokyo
Hitoshi Kurumizaka
Hitoshi Kurumizaka University of Tokyo
Susumu Nishimura
Susumu Nishimura University of Tsukuba
Peter Güntert
Peter Güntert ETH Zurich

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