Shigeyuki Yokoyama

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award
• 2025 - Research.com Biology and Biochemistry in Japan Leader Award
• 2023 - Research.com Biology and Biochemistry in Japan Leader Award
• 2011 - Fellow of the American Academy of Arts and Sciences

Overview

Best Publications

• Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains.

  Hideo Ogiso;Ryuichiro Ishitani;Osamu Nureki;Shuya Fukai

  1519
  Citations

• An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

  Antony W. Burgess;Hyun Soo Cho;Hyun Soo Cho;Charles Eigenbrot;Kathryn M. Ferguson

  1255
  Citations

• Protein production and purification.

  S Gräslund

  1004
  Citations

• Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution

  Dmitry G. Vassylyev;Shun-ichi Sekine;Oleg Laptenko;Jookyung Lee

  929
  Citations

• Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer

  Balasundaram Padmanabhan;Kit I. Tong;Tsutomu Ohta;Yoshihiro Nakamura

  816
  Citations

• Structural Basis for RNA Unwinding by the DEAD-Box Protein Drosophila Vasa

  Toru Sengoku;Osamu Nureki;Akira Nakamura;Satoru Kobayashi

  643
  Citations

• Codon and amino-acid specificities of a transfer RNA are both converted by a single post-transcriptional modification.

  Tomonari Muramatsu;Kazuya Nishikawa;Fumiko Nemoto;Yoshiyuki Kuchino

  619
  Citations

• CELL-FREE PRODUCTION AND STABLE-ISOTOPE LABELING OF MILLIGRAM QUANTITIES OF PROTEINS

  Takanori Kigawa;Takashi Yabuki;Yasuhiko Yoshida;Michio Tsutsui

  583
  Citations

• Role of the ENTH Domain in Phosphatidylinositol-4,5-Bisphosphate Binding and Endocytosis

  Toshiki Itoh;Seizo Koshiba;Takanori Kigawa;Akira Kikuchi

  582
  Citations

• An operational RNA code for amino acids and possible relationship to genetic code.

  Paul Schimmel;Richard Giege;Dino Moras;Shigeyuki Yokoyama

  531
  Citations

• Generation of high-affinity DNA aptamers using an expanded genetic alphabet.

  Michiko Kimoto;Rie Yamashige;Ken-ichiro Matsunaga;Shigeyuki Yokoyama

  530
  Citations

• Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein.

  Noriko Handa;Osamu Nureki;Kazuki Kurimoto;Insil Kim

  528
  Citations

• Molecular computation by DNA hairpin formation.

  Kensaku Sakamoto;Hidetaka Gouzu;Ken Komiya;Daisuke Kiga

  516
  Citations

• Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis

  Atsushi Shimada;Hideaki Niwa;Kazuya Tsujita;Shiro Suetsugu;Shiro Suetsugu

  502
  Citations

• Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.

  Kit I. Tong;Balasundaram Padmanabhan;Akira Kobayashi;Chengwei Shang

  475
  Citations

• Enzyme structure with two catalytic sites for double-sieve selection of substrate.

  Osamu Nureki;Dmitry G. Vassylyev;Masaru Tateno;Atsushi Shimada

  463
  Citations

• Structural genomics projects in Japan.

  Shigeyuki Yokoyama;Hiroshi Hirota;Takanori Kigawa;Takashi Yabuki

  461
  Citations

• Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

  Motoaki Wakiyama;Koji Takimoto;Osamu Ohara;Shigeyuki Yokoyama

  455
  Citations

• Regulation through the Secondary Channel—Structural Framework for ppGpp-DksA Synergism during Transcription

  Anna Perederina;Vladimir Svetlov;Marina N Vassylyeva;Tahir H Tahirov

  425
  Citations

• Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase

  Kliment A. Verba;Ray Yu-Ruei Wang;Akihiko Arakawa;Yanxin Liu

  422
  Citations