D-Index & Metrics Best Publications
Biology and Biochemistry
Japan
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 129 Citations 60,961 1,221 World Ranking 302 National Ranking 12

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Japan Leader Award

2011 - Fellow of the American Academy of Arts and Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Shigeyuki Yokoyama mostly deals with Biochemistry, Stereochemistry, Transfer RNA, Cell biology and RNA. His work on Biochemistry deals in particular with DNA, Amino acid, T7 RNA polymerase, Escherichia coli and Thermus thermophilus. His Stereochemistry research incorporates themes from Protein structure, Crystallography, Base pair and Guanosine.

His work carried out in the field of Transfer RNA brings together such families of science as Genetic code, Ribosome and Active site. Shigeyuki Yokoyama has researched Cell biology in several fields, including Genetics, Transcription factor, Mutant, Molecular biology and RNA-binding protein. His studies in RNA integrate themes in fields like Nucleic acid and Nucleotide.

His most cited work include:

  • Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains. (953 citations)
  • An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors (748 citations)
  • Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution (659 citations)

What are the main themes of his work throughout his whole career to date?

Biochemistry, Stereochemistry, Transfer RNA, Crystallography and Cell biology are his primary areas of study. His Biochemistry research focuses on Amino acid, Thermus thermophilus, RNA, Escherichia coli and Protein structure. The various areas that Shigeyuki Yokoyama examines in his Protein structure study include Biophysics, Peptide sequence and Binding site.

Shigeyuki Yokoyama interconnects Base pair, Nucleic acid, Nucleotide and Enzyme in the investigation of issues within Stereochemistry. The Transfer RNA study combines topics in areas such as Genetic code and Protein biosynthesis. His work deals with themes such as Molecular biology and Genetics, which intersect with Cell biology.

He most often published in these fields:

  • Biochemistry (40.58%)
  • Stereochemistry (25.10%)
  • Transfer RNA (17.09%)

What were the highlights of his more recent work (between 2012-2021)?

  • Biochemistry (40.58%)
  • Cell biology (12.20%)
  • Stereochemistry (25.10%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Biochemistry, Cell biology, Stereochemistry, Molecular biology and Biophysics. Transfer RNA, Amino acid, Protein structure, Cell-free protein synthesis and Escherichia coli are among the areas of Biochemistry where Shigeyuki Yokoyama concentrates his study. He focuses mostly in the field of Cell biology, narrowing it down to topics relating to RNA and, in certain cases, Nucleic acid and DNA.

His studies deal with areas such as Peptide, Aquifex aeolicus, Thermus thermophilus and Enzyme as well as Stereochemistry. His Molecular biology study integrates concerns from other disciplines, such as RNA polymerase II and Transcription. His Biophysics study combines topics in areas such as Acetabularia and Membrane protein.

Between 2012 and 2021, his most popular works were:

  • A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity (396 citations)
  • Generation of high-affinity DNA aptamers using an expanded genetic alphabet. (296 citations)
  • Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase (206 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Shigeyuki Yokoyama focuses on Biochemistry, Cell biology, Protein structure, Transfer RNA and Stereochemistry. His research combines Biophysics and Biochemistry. His Cell biology research includes themes of Cell, Molecular biology, Cleavage, Protein biosynthesis and Dock2.

The concepts of his Protein structure study are interwoven with issues in Crystallography, Hsp90, Guanine nucleotide exchange factor, Ground state and Unfolded protein response. His Transfer RNA study combines topics from a wide range of disciplines, such as Amino acid, Genetic code and Base pair. His Stereochemistry study incorporates themes from Residue and Homology modeling.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains.

Hideo Ogiso;Ryuichiro Ishitani;Osamu Nureki;Shuya Fukai.
Cell (2002)

1300 Citations

An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

Antony W. Burgess;Hyun Soo Cho;Hyun Soo Cho;Charles Eigenbrot;Kathryn M. Ferguson.
Molecular Cell (2003)

1204 Citations

Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution

Dmitry G. Vassylyev;Shun-ichi Sekine;Oleg Laptenko;Jookyung Lee.
Nature (2002)

858 Citations

Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer

Balasundaram Padmanabhan;Kit I. Tong;Tsutomu Ohta;Yoshihiro Nakamura.
Molecular Cell (2006)

734 Citations

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

Miki Okada-Iwabu;Toshimasa Yamauchi;Masato Iwabu;Teruki Honma.
Nature (2013)

709 Citations

Structural Basis for RNA Unwinding by the DEAD-Box Protein Drosophila Vasa

Toru Sengoku;Osamu Nureki;Akira Nakamura;Satoru Kobayashi.
Cell (2006)

596 Citations

Codon and amino-acid specificities of a transfer RNA are both converted by a single post-transcriptional modification.

Tomonari Muramatsu;Kazuya Nishikawa;Fumiko Nemoto;Yoshiyuki Kuchino.
Nature (1988)

578 Citations

Role of the ENTH Domain in Phosphatidylinositol-4,5-Bisphosphate Binding and Endocytosis

Toshiki Itoh;Seizo Koshiba;Takanori Kigawa;Akira Kikuchi.
Science (2001)

567 Citations

CELL-FREE PRODUCTION AND STABLE-ISOTOPE LABELING OF MILLIGRAM QUANTITIES OF PROTEINS

Takanori Kigawa;Takashi Yabuki;Yasuhiko Yoshida;Michio Tsutsui.
FEBS Letters (1999)

563 Citations

Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein.

Noriko Handa;Osamu Nureki;Kazuki Kurimoto;Insil Kim.
Nature (1999)

491 Citations

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