World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
29669
World Ranking
2813
National Ranking
204

Overview

Jason W. Chin is affiliated with the MRC Laboratory of Molecular Biology in the United Kingdom. Their research primarily falls within the field of Biochemistry, Genetics, and Molecular Biology, with substantial contributions to several specialized subfields including Molecular Biology, Genetics, Endocrine and Autonomic Systems, Surgery, and Biomedical Engineering.

The scientist's work focuses on key topics such as RNA and protein synthesis mechanisms, bacterial genetics and biotechnology, RNA modifications and cancer, circadian rhythm and melatonin, genomics and phylogenetic studies, CRISPR and genetic engineering, as well as chemical synthesis and analysis.

Jason W. Chin has published multiple papers in notable scientific journals. Among recent publications are:

  • Reprogramming the genetic code, 2020, Nature Reviews Genetics
  • Sense codon reassignment enables viral resistance and encoded polymer synthesis, 2021, Science
  • Engineered triply orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids, 2020, Nature Chemistry
  • Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase-tRNA pairs, 2020, Nature Biotechnology
  • Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms, 2020, Nature

Frequent co-authors include:

  • Louise F. H. Funke
  • Wesley E. Robertson
  • Thomas Elliott
  • Kim C. Liu
  • Shan Tang

Their publications are often featured in venues such as bioRxiv (Cold Spring Harbor Laboratory), Science, Nature Chemistry, Nature, and Proceedings of the National Academy of Sciences, reflecting an active presence in high-impact scientific outlets.

Best Publications

  • Regulation of cellular metabolism by protein lysine acetylation.

    Shimin Zhao;Wei Xu;Wenqing Jiang;Wei Yu

  • Addition of p-Azido-l-phenylalanine to the Genetic Code of Escherichia coli

    Jason W. Chin;Stephen W. Santoro;Andrew B. Martin;David S. King

  • An Expanded Eukaryotic Genetic Code

    Jason W. Chin;T. Ashton Cropp;J. Christopher Anderson;Mridul Mukherji

  • Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins

    Kathrin Lang;Jason W. Chin

  • Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli

    Jason W. Chin;Andrew B. Martin;David S. King;Lei Wang

  • Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

    Heinz Neumann;Kaihang Wang;Lloyd Davis;Maria Garcia-Alai

  • Genetically encoding N|[epsi]|-acetyllysine in recombinant proteins

    Heinz Neumann;Sew Y Peak-Chew;Jason W Chin

  • Genetic Encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions.

    Kathrin Lang;Lloyd Davis;Stephen Wallace;Mohan Mahesh

  • Expanding and reprogramming the genetic code.

    Jason W. Chin

  • Adding Amino Acids with Novel Reactivity to the Genetic Code of Saccharomyces Cerevisiae

    Alexander Deiters;T Ashton Cropp;Mridul Mukherji;Jason W Chin

  • Bioorthogonal Reactions for Labeling Proteins

    Kathrin Lang;Jason W. Chin

  • A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation

    Heinz Neumann;Susan M. Hancock;Ruth Buning;Andrew Routh

  • Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

    Kathrin Lang;Lloyd Davis;Jessica Torres-Kolbus;Chungjung Chou

  • Expanding and Reprogramming the Genetic Code of Cells and Animals

    Jason W Chin

  • Total synthesis of Escherichia coli with a recoded genome

    Julius Fredens;Kaihang Wang;Kaihang Wang;Daniel de la Torre;Louise F. H. Funke

  • Designer proteins: applications of genetic code expansion in cell biology.

    Lloyd Davis;Jason W. Chin

  • Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteins via a Pyrrolysyl-tRNA Synthetase/tRNACUA Pair and Click Chemistry

    Duy P Nguyen;Hrvoje Lusic;Heinz Neumann;Prashant B Kapadnis

  • In vivo incorporation of unnatural amino acids

    Peter Schultz;Lei Wang;John Christopher Anderson;Jason William Chin

  • A network of orthogonal ribosome·mRNA pairs

    Oliver Rackham;Jason W Chin

  • Evolved orthogonal ribosomes enhance the efficiency of synthetic genetic code expansion

    Kaihang Wang;Heinz Neumann;Sew Y Peak-Chew;Jason W Chin

Frequent Co-Authors

Peter G. Schultz
Peter G. Schultz Scripps Research Institute
Alexander Deiters
Alexander Deiters University of Pittsburgh
Lei Wang
Lei Wang University of California, San Francisco
Eric Meggers
Eric Meggers Philipp University of Marburg
David R. Liu
David R. Liu Broad Institute
Lloyd S. Davis
Lloyd S. Davis University of Otago
Leo C. James
Leo C. James MRC Laboratory of Molecular Biology
Philippe I. H. Bastiaens
Philippe I. H. Bastiaens Max Planck Society
Alanna Schepartz
Alanna Schepartz University of California, Berkeley
Richard Bayliss
Richard Bayliss University of Leeds

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