World's Best Scientists 2026 revealed!
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Ashraf Brik

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
11317
World Ranking
11521
National Ranking
109

Chemistry

D-Index
59
Citations
10816
World Ranking
10293
National Ranking
72

Ashraf Brik publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Ashraf Brik sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 173 publications — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Ashraf Brik D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Ashraf Brik sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 59 D-Index — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Ashraf Brik is affiliated with the Technion - Israel Institute of Technology in Israel. Their research focuses broadly on Biochemistry, Genetics, and Molecular Biology, with specific concentrations in Molecular Biology, Oncology, Organic Chemistry, Cell Biology, and Genetics.

The primary topics addressed in Ashraf Brik's work include:

  • Ubiquitin and proteasome pathways
  • Protein degradation and inhibitors
  • Peptidase inhibition and analysis
  • Chemical synthesis and analysis
  • Click chemistry and applications
  • Glycosylation and glycoproteins research
  • RNA interference and gene delivery

Recent publications by Ashraf Brik exemplify their research scope and include the following papers:

  • "The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag," 2021, Nature Communications
  • "General synthetic strategy for regioselective ultrafast formation of disulfide bonds in peptides and proteins," 2021, Nature Communications
  • "Enhanced Live-Cell Delivery of Synthetic Proteins Assisted by Cell-Penetrating Peptides Fused to DABCYL," 2021, Angewandte Chemie International Edition
  • "On-Demand Detachment of Succinimides on Cysteine to Facilitate (Semi)Synthesis of Challenging Proteins," 2020, Journal of the American Chemical Society
  • "Harnessing the power of transition metals in solid-phase peptide synthesis and key steps in the (semi)synthesis of proteins," 2021, Chemical Society Reviews

Ashraf Brik frequently publishes in specific scientific venues including:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Nature Communications
  • Journal of the American Chemical Society
  • Chemical Science

The scientist collaborates regularly with several coauthors, reflecting ongoing research partnerships. Frequent coauthors include:

  • Shaswati Mandal
  • Guy Mann
  • Ganga B. Vamisetti
  • Hiroaki Suga
  • Abhishek Saha

Best Publications

  • HIV-1 protease: mechanism and drug discovery

    Ashraf Brik;Chi-Huey Wong

  • Small molecules targeting severe acute respiratory syndrome human coronavirus

    Chung Yi Wu;Jia Tsrong Jan;Shiou Hwa Ma;Chin Jung Kuo

  • 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors.

    Ashraf Brik;Jerry Alexandratos;Ying-Chuan Lin;John H. Elder

  • Expanding the chemical toolbox for the synthesis of large and uniquely modified proteins

    Somasekhar Bondalapati;Muhammad Jbara;Ashraf Brik

  • A Copper(I)-Catalyzed 1,2,3-Triazole Azide−Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant

    Michael J. Giffin;Holly Heaslet;Ashraf Brik;Ying-Chuan Lin

  • Highly efficient and chemoselective peptide ubiquitylation.

    K. S. Ajish Kumar;Mahmood Haj-Yahya;Diana Olschewski;Hilal A. Lashuel

  • Structural basis for histone H2B deubiquitination by the SAGA DUB module.

    Michael T. Morgan;Mahmood Haj-Yahya;Alison E. Ringel;Prasanthi Bandi

  • Total Chemical Synthesis of a 304 Amino Acid K48‐Linked Tetraubiquitin Protein

    K. S. Ajish Kumar;Sudhir N. Bavikar;Liat Spasser;Tal Moyal

  • RNF20 and USP44 Regulate Stem Cell Differentiation by Modulating H2B Monoubiquitylation

    Gilad Fuchs;Efrat Shema;Rita Vesterman;Eran Kotler

  • Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors.

    Ashraf Brik;John Muldoon;Ying-Chuan Lin;John H. Elder

  • The Size of the Proteasomal Substrate Determines Whether Its Degradation Will Be Mediated by Mono- Or Polyubiquitylation

    Nitzan Shabek;Yifat Herman-Bachinsky;Samuel Buchsbaum;Oded Lewinson

  • Total Chemical Synthesis of Di‐ubiquitin Chains

    K. S. Ajish Kumar;Liat Spasser;Lesly A. Erlich;Sudhir N. Bavikar

  • Efficient Palladium-Assisted One-Pot Deprotection of (Acetamidomethyl)Cysteine Following Native Chemical Ligation and/or Desulfurization To Expedite Chemical Protein Synthesis.

    Suman Kumar Maity;Muhammad Jbara;Shay Laps;Ashraf Brik

  • Protein Synthesis Assisted by Native Chemical Ligation at Leucine

    Ziv Harpaz;Peter Siman;K. S. Ajish Kumar;Ashraf Brik

  • Synthetic polyubiquitinated α-Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology

    Mahmood Haj-Yahya;Bruno Fauvet;Yifat Herman-Bachinsky;Mirva Hejjaoui

  • Palladium in the Chemical Synthesis and Modification of Proteins

    Muhammad Jbara;Suman Kumar Maity;Ashraf Brik

  • Sugar-Assisted Glycopeptide Ligation

    Ashraf Brik;Yu-Ying Yang;Simon Ficht;Chi-Huey Wong

  • Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34.

    Peter Siman;Subramanian Vedhanarayanan Karthikeyan;Miroslav Nikolov;Wolfgang Fischle

  • Chemistry and Biology of the Ubiquitin Signal

    Liat Spasser;Ashraf Brik

  • The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.

    Indrajit Sahu;Sachitanand M. Mali;Prasad Sulkshane;Cong Xu

  • N-methylcysteine-mediated total chemical synthesis of ubiquitin thioester.

    Lesly A. Erlich;K. S. Ajish Kumar;Mahmood Haj-Yahya;Philip E. Dawson

Frequent Co-Authors

Chi-Huey Wong
Chi-Huey Wong Scripps Research Institute
Aaron Ciechanover
Aaron Ciechanover Technion – Israel Institute of Technology
Ehud Keinan
Ehud Keinan Technion – Israel Institute of Technology
Hilal A. Lashuel
Hilal A. Lashuel École Polytechnique Fédérale de Lausanne
Cynthia Wolberger
Cynthia Wolberger Johns Hopkins University School of Medicine
Richard J. Payne
Richard J. Payne University of Sydney
John H. Elder
John H. Elder Scripps Research Institute
Philip E. Dawson
Philip E. Dawson Scripps Research Institute
Chung-Yi Wu
Chung-Yi Wu Academia Sinica
David Fushman
David Fushman University of Maryland, College Park

External Links

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