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Chemistry

D-Index
88
Citations
29939
World Ranking
2271
National Ranking
814

Research.com Recognitions

  • 2001 - Fellow of Alfred P. Sloan Foundation

Overview

Philip E. Dawson is affiliated with the Scripps Research Institute in the United States. Their research focuses primarily on the broad field of Biochemistry, Genetics, and Molecular Biology, with substantial work in the subfields of Molecular Biology, Organic Chemistry, Oncology, Biomaterials, and Cellular and Molecular Neuroscience.

Their work addresses several main topics including Chemical Synthesis and Analysis, Peptidase Inhibition and Analysis, Advanced Biosensing and Bioanalysis Techniques, Click Chemistry and Applications, Enzyme Catalysis and Immobilization, RNA and Protein Synthesis Mechanisms, and DNA and Nucleic Acid Chemistry.

Notable recent publications include:

  • Recent Advances in Biocatalysis with Chemical Modification and Expanded Amino Acid Alphabet, 2021, Chemical Reviews
  • Serine-Selective Bioconjugation, 2020, Journal of the American Chemical Society
  • DNA Encoded Libraries: A Visitor's Guide, 2020, Israel Journal of Chemistry
  • RASS-Enabled S/P−C and S−N Bond Formation for DEL Synthesis, 2020, Angewandte Chemie International Edition
  • Improving the Gastrointestinal Stability of Linaclotide, 2021, Journal of Medicinal Chemistry

Frequent co-authors collaborating with Dawson have included Dillon T. Flood, Julien C. Vantourout, Phil S. Baran, Hyungdon Yun, and Kyle W. Knouse.

Their publications are often featured in venues such as ACS Central Science, FASEB BioAdvances, Journal of the American Chemical Society, Angewandte Chemie International Edition, and Journal of Medicinal Chemistry.

Philip E. Dawson received the Alfred P. Sloan Foundation Fellowship in 2001.

Best Publications

  • Synthesis of proteins by native chemical ligation

    Stephen B. H. Kent;Tom W. Muir;Philip E. Dawson

  • Synthesis of native proteins by chemical ligation.

    Philip E. Dawson;Stephen B. H. Kent

  • Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology

    Tilman M. Hackeng;John H. Griffin;Philip E. Dawson

  • Synthesis of Peptides and Proteins without Cysteine Residues by Native Chemical Ligation Combined with Desulfurization

    Liang Z. Yan;Philip E. Dawson

  • Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates.

    Igor L. Medintz;Aaron R. Clapp;Florence M. Brunel;Theresa Tiefenbrunn

  • An Efficient Fmoc-SPPS Approach for the Generation of Thioester Peptide Precursors for Use in Native Chemical Ligation

    Juan B. Blanco-Canosa;Philip E. Dawson

  • Nucleophilic Catalysis of Oxime Ligation

    Anouk Dirksen;Tilman M. Hackeng;Philip E. Dawson

  • Single-molecule protein folding: diffusion fluorescence resonance energy transfer studies of the denaturation of chymotrypsin inhibitor 2.

    Ashok A. Deniz;Ted A. Laurence;Gangamani S. Beligere;Maxime Dahan

  • The Controlled Display of Biomolecules on Nanoparticles: A Challenge Suited to Bioorthogonal Chemistry

    W. Russ Algar;Duane E. Prasuhn;Michael H. Stewart;Travis L. Jennings

  • Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing.

    Igor L. Medintz;Michael H. Stewart;Scott A. Trammell;Kimihiro Susumu

  • Nucleophilic catalysis of hydrazone formation and transimination: implications for dynamic covalent chemistry.

    Anouk Dirksen;Sjoerd Dirksen;Tilman M Hackeng;Philip E Dawson

  • Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size

    Eunkeu Oh;James B Delehanty;Kim E Sapsford;Kimihiro Susumu

  • High-efficiency labeling of sialylated glycoproteins on living cells.

    Ying Zeng;T N C Ramya;Anouk Dirksen;Philip E Dawson

  • Rapid Oxime and Hydrazone Ligations with Aromatic Aldehydes for Biomolecular Labeling

    Anouk Dirksen;Philip E. Dawson

  • Modulation of Reactivity in Native Chemical Ligation through the Use of Thiol Additives

    Philip E. Dawson;Michael J. Churchill;M. Reza Ghadiri;Stephen B. H. Kent

  • Self-assembled quantum dot-peptide bioconjugates for selective intracellular delivery.

    James B. Delehanty;Igor L. Medintz;Thomas Pons;Florence M. Brunel

  • A sulfilimine bond identified in collagen IV.

    Roberto Vanacore;Amy-Joan L. Ham;Markus Voehler;Charles R. Sanders

  • Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles.

    Kimihiro Susumu;Eunkeu Oh;James B. Delehanty;Juan B. Blanco-Canosa

  • Extending synthetic access to proteins with a removable acyl transfer auxiliary

    John Offer;C N C Boddy;Philip E Dawson

  • Context-dependent contributions of backbone hydrogen bonding to β-sheet folding energetics

    Songpon Deechongkit;Houbi Nguyen;Evan T. Powers;Philip E. Dawson

  • Quantum Dots as Simultaneous Acceptors and Donors in Time-Gated Förster Resonance Energy Transfer Relays: Characterization and Biosensing

    W Russ Algar;David Wegner;Alan L Huston;Juan B Blanco-Canosa

Frequent Co-Authors

Igor L. Medintz
Igor L. Medintz United States Naval Research Laboratory
Kimihiro Susumu
Kimihiro Susumu United States Naval Research Laboratory
Stephen B. H. Kent
Stephen B. H. Kent University of Chicago
Hedi Mattoussi
Hedi Mattoussi Florida State University
Jeffrey R. Deschamps
Jeffrey R. Deschamps United States Naval Research Laboratory
Tom W. Muir
Tom W. Muir Princeton University
Floyd E. Romesberg
Floyd E. Romesberg Scripps Research Institute
Tilman M. Hackeng
Tilman M. Hackeng Maastricht University
Thomas Pons
Thomas Pons ESPCI Paris
Ehud Keinan
Ehud Keinan Technion – Israel Institute of Technology

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