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Chemistry

D-Index
74
Citations
14440
World Ranking
4851
National Ranking
1519

Biology and Biochemistry

D-Index
79
Citations
16945
World Ranking
4412
National Ranking
2143

Research.com Recognitions

  • 2019 - Fellow, National Academy of Inventors

Overview

Floyd E. Romesberg is affiliated with the Scripps Research Institute in the United States. Their research focuses predominantly on the fields of biochemistry, genetics, and molecular biology, with particular emphasis on molecular biology and genetics within these areas.

The scientist's work encompasses several subfields, including molecular biology, genetics, radiology, nuclear medicine and imaging, biomedical engineering, and ecology. Their research topics cover RNA and protein synthesis mechanisms, bacterial genetics and biotechnology, chemical synthesis and analysis, monoclonal and polyclonal antibodies research, RNA modifications and cancer, advanced biosensing and bioanalysis techniques, and bacteriophages and microbial interactions.

Frequent coauthors collaborating with Floyd E. Romesberg include Rebekah J. Karadeema, Ramanarayanan Krishnamurthy, Emil C. Fischer, Koji Hashimoto, and Aaron W. Feldman.

Publications by Floyd E. Romesberg have appeared mainly in the following venues:

  • Journal of the American Chemical Society
  • Nature Chemical Biology
  • Journal of Molecular Biology
  • Philosophical Transactions of the Royal Society B Biological Sciences
  • Journal of Natural Products

Recent papers authored or co-authored by Floyd E. Romesberg include:

  • New codons for efficient production of unnatural proteins in a semisynthetic organism, 2020, Nature Chemical Biology
  • Genetic Code Expansion: Inception, Development, Commercialization, 2021, Journal of the American Chemical Society
  • Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair, 2020, Journal of the American Chemical Society
  • Selection of Aptamers with Large Hydrophobic 2'-Substituents, 2020, Journal of the American Chemical Society
  • Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II, 2021, Nature Chemical Biology

Their contributions include studies on RNA and protein synthesis mechanisms and developments in genetic code expansion involving unnatural proteins and nucleic acids. Additional work addresses nanopore sequencing techniques and aptamer selection with hydrophobic modifications.

Floyd E. Romesberg was recognized as a Fellow of the National Academy of Inventors in 2019.

Best Publications

  • Inhibition of mutation and combating the evolution of antibiotic resistance.

    Ryan T Cirz;Jodie K Chin;David R Andes;Valérie de Crécy-Lagard

  • A semi-synthetic organism with an expanded genetic alphabet

    Denis A. Malyshev;Kirandeep Dhami;Thomas Lavergne;Tingjian Chen

  • A Novel Copper-Mediated DNA Base Pair

    Eric Meggers;Patrick L. Holland;William B. Tolman;Floyd E. Romesberg

  • A semi-synthetic organism that stores and retrieves increased genetic information.

    Yorke Zhang;Jerod L. Ptacin;Emil C. Fischer;Hans R. Aerni

  • Efforts toward Expansion of the Genetic Alphabet: DNA Polymerase Recognition of a Highly Stable, Self-Pairing Hydrophobic Base

    Dustin L. McMinn;Anthony K. Ogawa;Yiqin Wu;Jianquan Liu

  • Beyond A, C, G and T: augmenting nature’s alphabet

    Allison A Henry;Floyd E Romesberg

  • Efforts toward the Expansion of the Genetic Alphabet: Information Storage and Replication with Unnatural Hydrophobic Base Pairs

    Anthony K. Ogawa;Yiqin Wu;Dustin L. McMinn;Jianquan Liu

  • Defining the Pseudomonas aeruginosa SOS Response and Its Role in the Global Response to the Antibiotic Ciprofloxacin

    Ryan T. Cirz;Bryan M. O'Neill;Jennifer A. Hammond;Steven R. Head

  • Complete and SOS-Mediated Response of Staphylococcus aureus to the Antibiotic Ciprofloxacin

    Ryan T. Cirz;Marcus B. Jones;Neill A. Gingles;Timothy D. Minogue

  • Combating bacteria and drug resistance by inhibiting mechanisms of persistence and adaptation

    Peter A Smith;Floyd E Romesberg

  • Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase.

    Gang Xia;Liangjing Chen;Takashi Sera;Ming Fa

  • Efforts toward expansion of the genetic alphabet: replication of DNA with three base pairs.

    Eunju Lee Tae;Yiqin Wu;Gang Xia;Peter G. Schultz

  • Immunological origins of binding and catalysis in a Diels-Alderase antibody.

    Floyd E. Romesberg;Ben Spiller;Peter G. Schultz;Raymond C. Stevens

  • The Expanded Genetic Alphabet.

    Denis A. Malyshev;Floyd E. Romesberg

  • Solvent-Dependent Photoinduced Tautomerization of 2-(2‘-Hydroxyphenyl)benzoxazole

    Osama K. Abou-Zied;Ralph Jimenez;Elizabeth H. Z. Thompson;David P. Millar

  • A semisynthetic organism engineered for the stable expansion of the genetic alphabet

    Yorke Zhang;Brian M. Lamb;Aaron W. Feldman;Anne Xiaozhou Zhou

  • Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet.

    Aaron M. Leconte;Gil Tae Hwang;Shigeo Matsuda;Petr Capek

  • Efforts toward Expansion of the Genetic Alphabet: Optimization of Interbase Hydrophobic Interactions

    Yiqin Wu;Anthony K. Ogawa;Markus Berger;Dustin L. McMinn

  • Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet

    Denis A. Malyshev;Kirandeep Dhami;Henry T. Quach;Thomas Lavergne

  • Pph3–Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage

    Bryan M. O'Neill;Shawn J. Szyjka;Ewa T. Lis;Aaron O. Bailey

Frequent Co-Authors

Peter G. Schultz
Peter G. Schultz Scripps Research Institute
David B. Collum
David B. Collum Cornell University
Philip E. Dawson
Philip E. Dawson Scripps Research Institute
Robyn L. Stanfield
Robyn L. Stanfield Scripps Research Institute
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Phil S. Baran
Phil S. Baran Scripps (United States)
Michal Hocek
Michal Hocek Czech Academy of Sciences
David A. Case
David A. Case Rutgers, The State University of New Jersey
Raymond C. Stevens
Raymond C. Stevens University of Southern California
Peter G. Wolynes
Peter G. Wolynes Rice University

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