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Lou Ann S. Brown

Lou Ann S. Brown

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
9866
World Ranking
13394
National Ranking
5692

Overview

Lou Ann S. Brown is affiliated with Emory University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a total of 61 and 16 publications respectively in these domains.

The scientist's work covers several subfields, including Genetics, Pediatrics, Perinatology and Child Health, Hematology, Molecular Biology, and Pulmonary and Respiratory Medicine. Major research topics addressed by Lou Ann S. Brown include:

  • Hemoglobinopathies and Related Disorders
  • Iron Metabolism and Disorders
  • Pharmacological Effects and Toxicity Studies
  • Metabolism and Genetic Disorders
  • Folate and B Vitamins Research
  • Peroxisome Proliferator-Activated Receptors
  • Hemoglobin structure and function

Their recent publications illustrate a focus on infectious disease mechanisms, mitochondrial function, and immune cell behavior. Notable papers include:

  • Altered amino acid profile in patients with SARS-CoV-2 infection, 2021, Proceedings of the National Academy of Sciences
  • Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain, 2020, Blood
  • Alcohol induces mitochondrial derangements in alveolar macrophages by upregulating NADPH oxidase 4, 2020, Alcohol
  • Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C), 2021, Experimental Biology and Medicine
  • Pioglitazone Reverses Alcohol-Induced Alveolar Macrophage Phagocytic Dysfunction, 2021, The Journal of Immunology

Lou Ann S. Brown frequently collaborates with a group of researchers including Frank Harris, Claudia R. Morris, Carlton Dampier, Rawan Korman, and Dunia Hatabah. The scientist has contributed extensively to several publication venues, with multiple articles appearing in Blood, PEDIATRICS, Alcohol, Experimental Biology and Medicine, and Nutrients.

Best Publications

  • Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC.

    Dean P Jones;Joanne L Carlson;Paula S Samiec;Paul Sternberg

  • Cytokines and Alcohol

    Fulton T. Crews;Rabih Bechara;Lou Ann Brown;David M. Guidot

  • Expression of highly selective sodium channels in alveolar type II cells is determined by culture conditions

    Lucky Jain;Xi-Juan Chen;Semra Ramosevac;Lou Ann Brown

  • Airway glutathione homeostasis is altered in children with severe asthma: Evidence for oxidant stress

    Anne M. Fitzpatrick;W. Gerald Teague;Fernando Holguin;Mary Yeh

  • High Dose Vitamin D Administration in Ventilated Intensive Care Unit Patients: A Pilot Double Blind Randomized Controlled Trial.

    Jenny E. Han;Jennifer L. Jones;Vin Tangpricha;Vin Tangpricha;Mona A. Brown

  • The molecular phenotype of severe asthma in children

    Anne M. Fitzpatrick;Melinda Higgins;Fernando Holguin;Lou Ann S. Brown

  • Protection against paraquat-induced injury by exogenous GSH in pulmonary alveolar type II cells

    Tory M. Hagen;Lou Ann Brown;Dean P. Jones

  • Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma

    Anne M. Fitzpatrick;Fernando Holguin;W. Gerald Teague;Lou Ann S. Brown

  • Healthy HIV-1-Infected Individuals on Highly Active Antiretroviral Therapy Harbor HIV-1 in Their Alveolar Macrophages

    Sushma K. Cribbs;Jeffrey Lennox;Angela M. Caliendo;Lou Ann Brown

  • Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats.

    F. Holguin;I. M. Moss;L. A. S. Brown;D. M. Guidot

  • Ethanol Induces Oxidative Stress in Alveolar Macrophages via Upregulation of NADPH Oxidases

    Samantha M. Yeligar;Frank L. Harris;C. Michael Hart;Lou Ann S. Brown

  • Ethanol ingestion via glutathione depletion impairs alveolar epithelial barrier function in rats.

    David M. Guidot;Katharina Modelska;Manuel Lois;Lucky Jain

  • Glutathione availability modulates alveolar macrophage function in the chronic ethanol-fed rat.

    Lou Ann S. Brown;Xiao-Du Ping;Frank L. Harris;Theresa W. Gauthier

  • Chronic ethanol ingestion and the risk of acute lung injury: a role for glutathione availability?

    Lou Ann S. Brown;Frank L. Harris;Xiao-Du Ping;Theresa W. Gauthier

  • Nitric oxide inhibits lung sodium transport through a cGMP-mediated inhibition of epithelial cation channels

    Lucky Jain;Xi-Juan Chen;Lou Ann Brown;Douglas C. Eaton

  • Chronic Ethanol Ingestion in Rats Decreases Granulocyte-Macrophage Colony-Stimulating Factor Receptor Expression and Downstream Signaling in the Alveolar Macrophage

    Pratibha C. Joshi;Lisa Applewhite;Jeffrey D. Ritzenthaler;Jesse Roman

  • Chronic ethanol ingestion potentiates TNF-α-mediated oxidative stress and apoptosis in rat type II cells

    Lou Ann S. Brown;Frank L. Harris;David M. Guidot

  • Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand.

    Karl L. Serrao;James D. Fortenberry;Marilyn L. Owens;Frank L. Harris

  • Influenza virus inhibits ENaC and lung fluid clearance.

    Xi Juan Chen;Shaguna Seth;Gang Yue;Pradip Kamat

  • Ethanol ingestion increases activation of matrix metalloproteinases in rat lungs during acute endotoxemia.

    M. Lois;L. A. S. Brown;I. M. Moss;J. Roman

Frequent Co-Authors

Anne M. Fitzpatrick
Anne M. Fitzpatrick Emory University
Dean P. Jones
Dean P. Jones Emory University
Vin Tangpricha
Vin Tangpricha Emory University
Jesse Roman
Jesse Roman Thomas Jefferson University
Thomas R. Ziegler
Thomas R. Ziegler Emory University
Douglas C. Eaton
Douglas C. Eaton Emory University
Fernando Holguin
Fernando Holguin University of Colorado Denver
Marc Moss
Marc Moss University of Colorado Anschutz Medical Campus
Elizabeth J. Kovacs
Elizabeth J. Kovacs University of Colorado Anschutz Medical Campus
Jeffrey L. Lennox
Jeffrey L. Lennox Emory University

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