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Chemistry

D-Index
50
Citations
8320
World Ranking
14452
National Ranking
1060

Overview

Andreas Marx is affiliated with the University of Konstanz in Germany and has made substantial contributions to the fields of biochemistry, genetics, and molecular biology. The scope of their research encompasses 159 publications in these areas, with significant work in medicine as well.

Their research can be further categorized into specialized subfields including molecular biology, oncology, physiology, genetics, and surgery. Among the main topics explored in their work are:

  • RNA modifications and cancer
  • Ubiquitin and proteasome pathways
  • Peptidase inhibition and analysis
  • RNA and protein synthesis mechanisms
  • Adenosine and purinergic signaling
  • Advanced biosensing and bioanalysis techniques
  • DNA and nucleic acid chemistry

Andreas Marx has published extensively in several high-profile venues, notable for the frequency of their contributions:

  • Cancer Research
  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • bioRxiv (Cold Spring Harbor Laboratory)
  • ChemBioChem

Examples of recent papers authored or co-authored by Andreas Marx include:

  • PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response, 2020, Nucleic Acids Research
  • Site-specific ubiquitylation acts as a regulator of linker histone H1, 2021, Nature Communications
  • Microenvironment-Sensitive Fluorescent Nucleotide Probes from Benzofuran, Benzothiophene, and Selenophene as Substrates for DNA Polymerases, 2022, Journal of the American Chemical Society
  • The Length of a Ubiquitin Chain: A General Factor for Selective Recognition by Ubiquitin-Binding Proteins, 2020, Angewandte Chemie International Edition
  • Chemoproteomic discovery of a human RNA ligase, 2023, Nature Communications

Their collaborative network includes frequent co-authors who have contributed to numerous publications together. Some of these include Guido Sauter, Sarah Minner, Ronald Simon, Maximilian Lennartz, and Till Krech.

Best Publications

  • Novel strategies for the site-specific covalent labelling of nucleic acids

    Samuel H. Weisbrod;Andreas Marx

  • Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain length.

    Jörg Fahrer;Ramon Kranaster;Matthias Altmeyer;Andreas H Marx

  • Structural Insights into the Processing of Nucleobase-Modified Nucleotides by DNA Polymerases

    Audrey Hottin;Andreas Marx

  • An Efficient Method for the Construction of Functionalized DNA Bearing Amino Acid Groups through Cross‐Coupling Reactions of Nucleoside Triphosphates Followed by Primer Extension or PCR

    Petr Čapek;Hana Cahová;Radek Pohl;Michal Hocek

  • Chemokine CXCL13 is overexpressed in the tumour tissue and in the peripheral blood of breast cancer patients

    J Panse;K Friedrichs;A Marx;Y Hildebrandt

  • Synthesis of defined ubiquitin dimers.

    Silvia Eger;Martin Scheffner;Andreas Marx;Marina Rubini

  • KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry.

    Karin Betz;Denis A Malyshev;Thomas Lavergne;Wolfram Welte

  • Rapid labeling of metabolically engineered cell-surface glycoconjugates with a carbamate-linked cyclopropene reporter.

    Anne-Katrin Späte;Holger Bußkamp;Andrea Niederwieser;Verena F. Schart

  • A nucleoside triphosphate for site-specific labelling of DNA by the Staudinger ligation.

    Samuel H. Weisbrod;Andreas Marx

  • Replication through an abasic DNA lesion: structural basis for adenine selectivity

    Samra Obeid;Nina Blatter;Ramon Kranaster;Andreas Schnur

  • Enzymatic Synthesis of Multiple Spin-Labeled DNA

    Samra Obeid;Maxim Yulikov;Maxim Yulikov;Gunnar Jeschke;Gunnar Jeschke;Andreas Marx

  • Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates

    Konrad Bergen;Anna-Lena Steck;Stefan Strütt;Anna Baccaro

  • Genotyping--from genomic DNA to genotype in a single tube.

    Michael Strerath;Andreas Marx

  • Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase

    Samra Obeid;Anna Baccaro;Wolfram Welte;Kay Diederichs

  • Direct Measurement of Electrical Transport Through G‐Quadruplex DNA with Mechanically Controllable Break Junction Electrodes

    Shou-Peng Liu;Samuel H. Weisbrod;Zhuo Tang;Andreas Marx

  • Aluminum Bis(trifluoromethylsulfonyl)amides: New Highly Efficient and Remarkably Versatile Catalysts for C - C Bond Formation Reactions.

    Andreas Marx;Hisashi Yamamoto

  • Evolving thermostable reverse transcriptase activity in a DNA polymerase scaffold.

    Katharina B. M. Sauter;Andreas Marx

  • Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design

    Daniel Summerer;Nicolas Z. Rudinger;Ilka Detmer;Andreas Marx

  • DNA‐Templated Synthesis: More Versatile than Expected

    Daniel Summerer;Andreas Marx

  • Orientational Properties of Poly‐γ‐benzyl‐<scp>L</scp>‐glutamate: Influence of Molecular Weight and Solvent on Order Parameters of the Solute

    Unknown

  • Structural insights into DNA replication without hydrogen bonds

    Karin Betz;Denis A. Malyshev;Thomas Lavergne;Wolfram Welte

  • Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation

    Anette Brockmann;Andrej Bluwstein;Annika Kögel;Sarah May

Frequent Co-Authors

Martin Scheffner
Martin Scheffner University of Konstanz
Kay Diederichs
Kay Diederichs University of Konstanz
Guido Sauter
Guido Sauter Universität Hamburg
Jakob R. Izbicki
Jakob R. Izbicki Universität Hamburg
Wolfram Welte
Wolfram Welte University of Konstanz
Ronald Simon
Ronald Simon Universität Hamburg
Andreas Zumbusch
Andreas Zumbusch University of Konstanz
Bernd Giese
Bernd Giese University of Fribourg
Marcel Leist
Marcel Leist University of Konstanz
Britta Siegmund
Britta Siegmund Humboldt-Universität zu Berlin

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