World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
73
Citations
20138
World Ranking
4928
National Ranking
357

Biology and Biochemistry

D-Index
74
Citations
20375
World Ranking
5582
National Ranking
403

Overview

Kay Diederichs is affiliated with the University of Konstanz in Germany. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with an emphasis on Molecular Biology, Materials Chemistry, Ecology, Genetics, and Biotechnology.

Their scientific work covers various main topics including:

  • Enzyme Structure and Function
  • Protein Structure and Dynamics
  • RNA and protein synthesis mechanisms
  • Bacteriophages and microbial interactions
  • Cancer Research and Treatments
  • RNA modifications and cancer
  • Peptidase Inhibition and Analysis

Diederichs has published in multiple venues, with frequent contributions to:

  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Applied Crystallography
  • Journal of the American Chemical Society
  • Nature Communications

Recent papers authored or co-authored by Kay Diederichs include:

  • "PDBx/mmCIF Ecosystem: Foundational Semantic Tools for Structural Biology," 2022, Journal of Molecular Biology
  • "NAC controls cotranslational N-terminal methionine excision in eukaryotes," 2023, Science
  • "XDSGUI: a graphical user interface for XDS, SHELX and ARCIMBOLDO", 2023, Journal of Applied Crystallography
  • "Paired refinement under the control ofPAIREF," 2020, IUCrJ
  • "Microenvironment-Sensitive Fluorescent Nucleotide Probes from Benzofuran, Benzothiophene, and Selenophene as Substrates for DNA Polymerases," 2022, Journal of the American Chemical Society

The scientist regularly collaborates with several co-authors, notably:

  • Olga Mayans
  • Martin Malý
  • Jan Dohnálek
  • Petr Kolenko
  • Barbara Franke

Best Publications

  • Linking crystallographic model and data quality.

    P. Andrew Karplus;Kay Diederichs

  • Improved R-factors for diffraction data analysis in macromolecular crystallography

    Kay Diederichs;P. Andrew Karplus

  • Siderophore-mediated iron transport: crystal structure of FhuA with bound lipopolysaccharide.

    Andrew D. Ferguson;Eckhard Hofmann;James W. Coulton;Kay Diederichs

  • Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

    Yanyong Kang;X. Edward Zhou;Xiang Gao;Yuanzheng He

  • Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

    Markus A. Seeger;André Schiefner;Thomas Eicher;François Verrey

  • Mechanism of the Stereocomplex Formation between Enantiomeric Poly(lactide)s

    Davide Brizzolara;Hans-Joachim Cantow;Kay Diederichs;Egbert Keller

  • Structural Basis of Light Harvesting by Carotenoids: Peridinin-Chlorophyll-Protein from Amphidinium carterae

    Eckhard Hofmann;Pamela M. Wrench;Frank P. Sharples;Roger G. Hiller

  • Structure of the rotor ring of F-Type Na+-ATPase from Ilyobacter tartaricus.

    Thomas Meier;Patrick Polzer;Patrick Polzer;Kay Diederichs;Kay Diederichs;Wolfram Welte;Wolfram Welte

  • Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis

    Kay Diederichs;Joachim Diez;Gerhard Greller;Christian Müller

  • Crystal structure of human β2‐glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome

    Robert Schwarzenbacher;Kornelius Zeth;Kay Diederichs;Anna Gries

  • Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

    Thomas Eicher;Hi-jea Cha;Markus A. Seeger;Lorenz Brandstätter

  • Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose.

    Doris Forst;Wolfram Welte;Thomas Wacker;Kay Diederichs

  • Better models by discarding data

    K. Diederichs;P. A. Karplus

  • Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor.

    Kay Diederichs;Tom Boone;P. Andrew Karplus

  • Recent developments in CrystFEL.

    Thomas A. White;Valerio Mariani;Wolfgang Brehm;Oleksandr Yefanov

  • Assessing and maximizing data quality in macromolecular crystallography

    P Andrew Karplus;Kay Diederichs

  • Structural basis of multivalent binding to wheat germ agglutinin.

    David Schwefel;Caroline Maierhofer;Johannes G. Beck;Sonja Seeberger

  • The x-ray structure of d-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation

    Stephan Umhau;Loredano Pollegioni;Gianluca Molla;Kay Diederichs

  • A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins

    Andrew D Ferguson;Andrew D Ferguson;Wolfram Welte;Eckhard Hofmann;Buko Lindner

  • Induced-fit movements in adenylate kinases

    Georg E. Schulz;Christoph W. Müller;Kay Diederichs

Frequent Co-Authors

Wolfram Welte
Wolfram Welte University of Konstanz
Andreas Marx
Andreas Marx University of Konstanz
Winfried Boos
Winfried Boos University of Konstanz
John R. Helliwell
John R. Helliwell University of Manchester
P. Andrew Karplus
P. Andrew Karplus Oregon State University
Martin Caffrey
Martin Caffrey Trinity College Dublin
François Verrey
François Verrey University of Zurich
Loredano Pollegioni
Loredano Pollegioni University of Insubria
Roger G. Hiller
Roger G. Hiller Macquarie University
Günter Fritz
Günter Fritz University of Hohenheim

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