What is he best known for?
The fields of study he is best known for:
- DNA
- Organic chemistry
- Catalysis
Michal Hocek mostly deals with DNA, Biochemistry, Stereochemistry, Nucleotide and DNA polymerase.
Michal Hocek has researched DNA in several fields, including Combinatorial chemistry and Organic chemistry.
His Biochemistry research focuses on subjects like Bioanalysis, which are linked to Chemical biology and Labelling.
The concepts of his Stereochemistry study are interwoven with issues in Sonogashira coupling, Aryl, Chemical synthesis and Purine.
His study in Nucleotide is interdisciplinary in nature, drawing from both Deoxyribonucleoside, Enzyme, Binding site and Pyrimidine.
In his study, DNA polymerase II is strongly linked to DNA clamp, which falls under the umbrella field of DNA polymerase.
His most cited work include:
- C-nucleosides: synthetic strategies and biological applications. (199 citations)
- Synthesis and cytostatic activity of substituted 6-phenylpurine bases and nucleosides: application of the Suzuki-Miyaura cross-coupling reactions of 6-chloropurine derivatives with phenylboronic acids. (171 citations)
- Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides. (124 citations)
What are the main themes of his work throughout his whole career to date?
Stereochemistry, DNA, Nucleotide, Combinatorial chemistry and Biochemistry are his primary areas of study.
His Stereochemistry research is multidisciplinary, incorporating elements of Aryl, Nucleic acid, Nucleophile and Purine.
DNA is closely attributed to Primer extension in his study.
His Combinatorial chemistry study incorporates themes from Redox, Sonogashira coupling and Nucleoside.
Biochemistry and Molecular biology are commonly linked in his work.
His Polymerase research integrates issues from Transcription and DNA synthesis.
He most often published in these fields:
- Stereochemistry (63.13%)
- DNA (53.28%)
- Nucleotide (34.17%)
What were the highlights of his more recent work (between 2016-2021)?
- DNA (53.28%)
- Stereochemistry (63.13%)
- Nucleotide (34.17%)
In recent papers he was focusing on the following fields of study:
His main research concerns DNA, Stereochemistry, Nucleotide, Polymerase and DNA polymerase.
His DNA research includes elements of Combinatorial chemistry and Primer extension.
His work carried out in the field of Stereochemistry brings together such families of science as Reductive amination, Aldehyde, Glycosylation and Nucleophile.
Michal Hocek interconnects RNA, Nucleic acid, Click chemistry and Enzyme in the investigation of issues within Nucleotide.
His Polymerase study combines topics in areas such as Restriction enzyme, Sonogashira coupling and DNA synthesis.
His research in DNA polymerase intersects with topics in Cytosine, Uracil, Deoxyadenosine, Deoxyribonucleoside and Fluorophore.
Between 2016 and 2021, his most popular works were:
- Pyrrolo[2,3‐d]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides (39 citations)
- Pyrrolo[2,3‐d]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides (39 citations)
- Enzymatic Synthesis of Base-Functionalized Nucleic Acids for Sensing, Cross-linking, and Modulation of Protein–DNA Binding and Transcription (27 citations)
In his most recent research, the most cited papers focused on:
- Organic chemistry
- DNA
- Enzyme
His scientific interests lie mostly in DNA, Stereochemistry, DNA polymerase, Nucleotide and Polymerase.
His DNA study introduces a deeper knowledge of Biochemistry.
His Stereochemistry research incorporates elements of Diol, Glycosylation and Nucleophile.
His DNA polymerase research includes themes of Uracil, Aminal, Primer extension, Deoxyribonucleoside and Oligonucleotide.
The various areas that Michal Hocek examines in his Nucleotide study include RNA and Pyrimidine.
His study looks at the relationship between Polymerase and topics such as Restriction enzyme, which overlap with Click chemistry and Deoxyribonucleoside triphosphate.
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