Michal Hocek

Overview

Best Publications

• C-nucleosides: synthetic strategies and biological applications.

  Jan Štambaský;Michal Hocek;Pavel Kočovský

  417
  Citations

• Synthesis and cytostatic activity of substituted 6-phenylpurine bases and nucleosides: application of the Suzuki-Miyaura cross-coupling reactions of 6-chloropurine derivatives with phenylboronic acids.

  Michal Hocek;Antonín Holý;and Ivan Votruba;Hana Dvořáková

  292
  Citations

• An Efficient Method for the Construction of Functionalized DNA Bearing Amino Acid Groups through Cross‐Coupling Reactions of Nucleoside Triphosphates Followed by Primer Extension or PCR

  Petr Čapek;Hana Cahová;Radek Pohl;Michal Hocek

  187
  Citations

• Cross-coupling reactions of nucleoside triphosphates followed by polymerase incorporation. Construction and applications of base-functionalized nucleic acids.

  Michal Hocek;Miroslav Fojta

  179
  Citations

• Aminophenyl- and nitrophenyl-labeled nucleoside triphosphates: synthesis, enzymatic incorporation, and electrochemical detection.

  Hana Cahová;Luděk Havran;Petra Brázdilová;Hana Pivoňková

  177
  Citations

• Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides.

  Michal Hocek;Petr Naus;Radek Pohl;Ivan Votruba

  176
  Citations

• Nucleobase modification as redox DNA labelling for electrochemical detection

  Michal Hocek;Miroslav Fojta

  173
  Citations

• Synthesis of base-modified 2'-deoxyribonucleoside triphosphates and their use in enzymatic synthesis of modified DNA for applications in bioanalysis and chemical biology.

  Michal Hocek

  164
  Citations

• Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines

  Petr Čapek;Radek Pohl;Michal Hocek

  158
  Citations

• Ferrocenylethynyl derivatives of nucleoside triphosphates: synthesis, incorporation, electrochemistry, and bioanalytical applications.

  Petra Brázdilová;Petra Brázdilová;Milan Vrábel;Radek Pohl;Hana Pivoňková

  152
  Citations

• Direct C-H arylation of purines: development of methodology and its use in regioselective synthesis of 2,6,8-trisubstituted purines.

  Igor Cerna;Radek Pohl;Blanka Klepetarová;Michal Hocek

  147
  Citations

• Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides

  Michal Hocek;Antonín Holý;Ivan Votruba;Hana Dvořáková

  146
  Citations

• Base‐Modified DNA Labeled by [Ru(bpy)3]2+ and [Os(bpy)3]2+ Complexes: Construction by Polymerase Incorporation of Modified Nucleoside Triphosphates, Electrochemical and Luminescent Properties, and Applications

  Milan Vrábel;Petra Horáková;Hana Pivoňková;Lubica Kalachova

  140
  Citations

• A Rotational BODIPY Nucleotide: An Environment‐Sensitive Fluorescence‐Lifetime Probe for DNA Interactions and Applications in Live‐Cell Microscopy

  Dmytro Dziuba;Piotr Jurkiewicz;Marek Cebecauer;Martin Hof

  137
  Citations

• Pyrrolo[2,3‐d]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides

  Pavla Perlíková;Michal Hocek;Michal Hocek

  135
  Citations

• Direct Polymerase Synthesis of Reactive Aldehyde‐Functionalized DNA and Its Conjugation and Staining with Hydrazines

  Veronika Raindlová;Radek Pohl;Miloslav Šanda;Michal Hocek

  133
  Citations

• Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines

  Aurelie Bourderioux;Petr Nauš;Pavla Perlíková;Radek Pohl

  131
  Citations

• Syntheses of Purines Bearing Carbon Substituents in Positions 2, 6 or 8 by Metal- or Organometal-Mediated C−C Bond-Forming Reactions

  Michal Hocek

  124
  Citations

• Enzymatic Synthesis of Base-Functionalized Nucleic Acids for Sensing, Cross-linking, and Modulation of Protein–DNA Binding and Transcription

  Michal Hocek;Michal Hocek

  118
  Citations

• 6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents.

  Petr Naus;Radek Pohl;Ivan Votruba;Petr Dzubák

  116
  Citations

• Synthesis and photophysical properties of biaryl-substituted nucleos(t)ides. Polymerase synthesis of DNA probes bearing solvatochromic and pH-sensitive dual fluorescent and 19F NMR labels.

  Jan Riedl;Radek Pohl;Lubomír Rulíšek;Michal Hocek

  113
  Citations