World's Best Scientists 2026 revealed!
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Chemistry
Germany
2026

D-Index & Metrics

Chemistry

D-Index
132
Citations
73393
World Ranking
290
National Ranking
25

Research.com Recognitions

  • 2026 - Research.com Chemistry in Germany Leader Award
  • 2025 - Research.com Chemistry in Germany Leader Award
  • 2022 - Research.com Chemistry in Germany Leader Award
  • 2015 - Paul Karrer Gold Medal, University of Zurich
  • 2009 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Chemistry
  • 1992 - Fellow of Alfred P. Sloan Foundation

Overview

Paul Knochel is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research contributions primarily lie within the field of Chemistry, with a strong focus on Organic Chemistry. The subfields of study in their work also include Inorganic Chemistry, Biomedical Engineering, Molecular Biology, and Pharmaceutical Science.

The scientist's work covers a range of main topics within chemical research, including:

  • Coordination Chemistry and Organometallics
  • Asymmetric Synthesis and Catalysis
  • Catalytic Cross-Coupling Reactions
  • Catalytic C-H Functionalization Methods
  • Asymmetric Hydrogenation and Catalysis
  • Synthesis of heterocyclic compounds
  • Synthesis and Catalytic Reactions

Paul Knochel has authored numerous scientific articles published predominantly in several respected venues. Frequent publication venues include:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Synthesis
  • Chemical Science
  • Organic Letters

Selected recent papers demonstrating the range of their work are:

  • Highly Regioselective Addition of Allylic Zinc Halides and Various Zinc Enolates to [1.1.1]Propellane, 2020, Angewandte Chemie International Edition
  • (2-Ethylhexyl)sodium: A Hexane-Soluble Reagent for Br/Na-Exchanges and Directed Metalations in Continuous Flow, 2021, Angewandte Chemie International Edition
  • Continuous Flow Preparation of Benzylic Sodium Organometallics, 2022, Angewandte Chemie International Edition
  • Continuous Flow Sodiation of Substituted Acrylonitriles, Alkenyl Sulfides and Acrylates, 2020, Angewandte Chemie International Edition
  • Regioselective functionalization of aryl azoles as powerful tool for the synthesis of pharmaceutically relevant targets, 2020, Nature Communications

The scientist has collaborated extensively with other researchers. Frequent coauthors include:

  • Konstantin Karaghiosoff
  • Johannes H. Harenberg
  • Alexander Kremsmair
  • Niels Weidmann
  • Andreas Hess

In recognition of their contributions, Paul Knochel has received several awards:

  • Paul Karrer Gold Medal, University of Zurich (2015)
  • Membership in the German National Academy of Sciences Leopoldina - Nationale Akademie der Wissenschaften (2009), Chemistry
  • Fellow of Alfred P. Sloan Foundation (1992)

Best Publications

  • Comprehensive organic synthesis

    Paul Knochel;Gary A. Molander

  • Preparation and reactions of polyfunctional organozinc reagents in organic synthesis

    Paul. Knochel;Robert D. Singer

  • A liCl-mediated Br/Mg exchange reaction for the preparation of functionalized aryl- and heteroarylmagnesium compounds from organic bromides

    Arkady Krasovskiy;Paul Knochel

  • Highly functionalized organomagnesium reagents prepared through halogen-metal exchange.

    Paul Knochel;Wolfgang Dohle;Nina Gommermann;Florian F. Kneisel

  • Synthesis and reactivity toward acyl chlorides and enones of the new highly functionalized copper reagents RCu(CN)ZnI

    Paul Knochel;Ming Chang P. Yeh;Scott C. Berk;Jason Talbert

  • Mixed Mg/Li Amides of the Type R2NMgCl⋅LiCl as Highly Efficient Bases for the Regioselective Generation of Functionalized Aryl and Heteroaryl Magnesium Compounds

    Arkady Krasovskiy;Valeria Krasovskaya;Paul Knochel

  • Enantioselective, Copper(I)‐Catalyzed Three‐Component Reaction for the Preparation of Propargylamines

    Nina Gommermann;Christopher Koradin;Kurt Polborn;Paul Knochel

  • Efficient Synthesis of Functionalized Organozinc Compounds by the Direct Insertion of Zinc into Organic Iodides and Bromides

    Arkady Krasovskiy;Vladimir Malakhov;Andrei Gavryushin;Paul Knochel

  • A Photoconductive Thienothiophene-Based Covalent Organic Framework Showing Charge Transfer Towards Included Fullerene

    Mirjam Dogru;Matthias Handloser;Florian Auras;Thomas Kunz

  • Recent Developments in Negishi Cross-Coupling Reactions

    Diana Haas;Jeffrey M. Hammann;Robert Greiner;Paul Knochel

  • Handbook of Functionalized Organometallics

    Paul Knochel

  • Mild and stereoselective hydroborations of functionalized alkynes and alkenes using pinacolborane

    Charles E. Tucker;Jessica Davidson;Paul Knochel

  • Regio- and chemoselective metalation of arenes and heteroarenes using hindered metal amide bases.

    Benjamin Haag;Marc Mosrin;Hiriyakkanavar Ila;Vladimir Malakhov

  • Soluble Lanthanide Salts (LnCl3⋅2 LiCl) for the Improved Addition of Organomagnesium Reagents to Carbonyl Compounds

    Arkady Krasovskiy;Felix Kopp;Paul Knochel

  • Enantioselective synthesis of propargylamines by copper-catalyzed addition of alkynes to enamines.

    Christopher Koradin;Kurt Polborn;Paul Knochel

  • ORGANOZINC MEDIATED REACTIONS

    Paul Knochel;Juan J. Almena Perea;Philip Jones

  • Oriented Films of Conjugated 2D Covalent Organic Frameworks as Photocathodes for Water Splitting.

    Torben Sick;Alexander G. Hufnagel;Jonathan Kampmann;Ilina Kondofersky

  • New Applications of Polyfunctional Organometallic Compounds in Organic Synthesis

    Andreas Boudier;Lars O. Bromm;Matthias Lotz;Paul Knochel

  • Eine LiCl‐vermittelte Br/Mg‐Austauschreaktion zur Herstellung funktionalisierter Aryl‐ und Heteroarylmagnesium‐Verbindungen ausgehend von organischen Bromiden

    Arkady Krasovskiy;Paul Knochel

  • (tmp)2Zn⋅2 MgCl2⋅2 LiCl: A Chemoselective Base for the Directed Zincation of Sensitive Arenes and Heteroarenes

    Stefan H. Wunderlich;Paul Knochel

Frequent Co-Authors

Konstantin Karaghiosoff
Konstantin Karaghiosoff Ludwig-Maximilians-Universität München
Peter Mayer
Peter Mayer Ludwig-Maximilians-Universität München
Ilan Marek
Ilan Marek Technion – Israel Institute of Technology
Herbert Mayr
Herbert Mayr Ludwig-Maximilians-Universität München
Hendrik Zipse
Hendrik Zipse Ludwig-Maximilians-Universität München
Thomas Bein
Thomas Bein Ludwig-Maximilians-Universität München
Gerard Cahiez
Gerard Cahiez Centre national de la recherche scientifique, CNRS
Kurt Polborn
Kurt Polborn Ludwig-Maximilians-Universität München
Guy Quéguiner
Guy Quéguiner Institut National des Sciences Appliquées de Rouen
Heinz Langhals
Heinz Langhals Ludwig-Maximilians-Universität München

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