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Chemistry

D-Index
99
Citations
33550
World Ranking
1349
National Ranking
518

Research.com Recognitions

  • 2019 - Fellow of the Indian National Academy of Engineering (INAE)
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kevin W. Plaxco is affiliated with the University of California, Santa Barbara in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, molecular biology, and engineering, with a strong emphasis on molecular biology and electrical and electronic engineering.

Plaxco has contributed extensively to the fields of advanced biosensing and bioanalysis techniques, electrochemical analysis and applications, and analytical chemistry and sensors. Their work also covers molecular junctions and nanostructures, electrochemical sensors and biosensors, as well as biosensors and analytical detection and receptor mechanisms and signaling.

The scientist's publication record includes numerous papers in leading venues. Frequent publication outlets include:

  • ACS Sensors
  • Angewandte Chemie International Edition
  • ECS Meeting Abstracts
  • Angewandte Chemie
  • Journal of the American Chemical Society

Notable recent papers authored by or involving Plaxco include:

  • "Elucidating the Mechanisms Underlying the Signal Drift of Electrochemical Aptamer-Based Sensors in Whole Blood," 2021, ACS Sensors
  • "Real-Time, In Vivo Molecular Monitoring Using Electrochemical Aptamer Based Sensors: Opportunities and Challenges," 2022, ACS Sensors
  • "Real-Time Monitoring of a Protein Biomarker," 2020, ACS Sensors
  • "Nanoporous Gold for the Miniaturization of In Vivo Electrochemical Aptamer-Based Sensors," 2021, ACS Sensors
  • "On the Disinfection of Electrochemical Aptamer-Based Sensors," 2022, ECS Sensors Plus

Plaxco collaborates frequently with several researchers, including:

  • Tod E. Kippin
  • Julian Gerson
  • Kaylyn K. Leung
  • Nicole Emmons
  • Francesco Ricci

In addition to articles, the scientist has contributed to book publications. One notable book titled "Astrobiology" was published in 2021 by Johns Hopkins University Press.

Plaxco has been recognized with fellowships from prestigious organizations, including:

  • Fellow of the Indian National Academy of Engineering (INAE), 2019
  • Fellow of the American Association for the Advancement of Science (AAAS), 2011

Best Publications

  • Contact order, transition state placement and the refolding rates of single domain proteins

    Kevin W Plaxco;Kim T Simons;David Baker

  • Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA.

    Chunhai Fan;Kevin W. Plaxco;Alan J. Heeger

  • Label-Free Electronic Detection of Thrombin in Blood Serum by Using an Aptamer-Based Sensor

    Yi Xiao;Arica A. Lubin;Alan J. Heeger;Kevin W. Plaxco

  • An Electronic, Aptamer-Based Small-Molecule Sensor for the Rapid, Label-Free Detection of Cocaine in Adulterated Samples and Biological Fluids

    Brian R. Baker;Rebecca Y. Lai;McCall S. Wood;Elaine H. Doctor

  • Random-coil behavior and the dimensions of chemically unfolded proteins

    Jonathan E. Kohn;Ian S. Millett;Jaby Jacob;Jaby Jacob;Bojan Zagrovic

  • A Reagentless Signal-On Architecture for Electronic, Aptamer-Based Sensors via Target-Induced Strand Displacement

    Yi Xiao;Brian D Piorek;Kevin W Plaxco;Alan J Heeger

  • Beyond superquenching: Hyper-efficient energy transfer from conjugated polymers to gold nanoparticles

    Chunhai Fan;Shu Wang;Janice W. Hong;Guillermo C. Bazan

  • High Specificity, Electrochemical Sandwich Assays Based on Single Aptamer Sequences and Suitable for the Direct Detection of Small-Molecule Targets in Blood and Other Complex Matrices

    Xiaolei Zuo;Yi Xiao;Kevin W. Plaxco

  • Colorimetric detection of DNA, small molecules, proteins, and ions using unmodified gold nanoparticles and conjugated polyelectrolytes

    Fan Xia;Xiaolei Zuo;Renqiang Yang;Yi Xiao

  • Folding-based electrochemical biosensors: the case for responsive nucleic acid architectures.

    Arica A. Lubin;Kevin W. Plaxco

  • Sensitive and Selective Amplified Fluorescence DNA Detection Based on Exonuclease III-Aided Target Recycling

    Xiaolei Zuo;Fan Xia;Yi Xiao;Kevin W Plaxco

  • Electrochemical detection of parts-per-billion lead via an electrode-bound DNAzyme assembly.

    Yi Xiao;and Aaron A. Rowe;Kevin W. Plaxco

  • Preparation of electrode-immobilized, redox-modified oligonucleotides for electrochemical DNA and aptamer-based sensing.

    Yi Xiao;Rebecca Y Lai;Kevin W Plaxco

  • Contact order revisited: Influence of protein size on the folding rate

    Dmitry N. Ivankov;Sergiy O. Garbuzynskiy;Eric Alm;Kevin W. Plaxco

  • Topology, stability, sequence, and length: Defining the determinants of two-state protein folding kinetics

    Kevin W. Plaxco;Kim T. Simons;Ingo Ruczinski;David Baker

  • Continuous, real-time monitoring of cocaine in undiluted blood serum via a microfluidic, electrochemical aptamer-based sensor.

    James S. Swensen;Yi Xiao;Brian S. Ferguson;Arica A. Lubin

  • Real-Time, Aptamer-Based Tracking of Circulating Therapeutic Agents in Living Animals

    Brian Scott Ferguson;David A. Hoggarth;Dan Maliniak;Kyle Ploense

  • Aptamer-Based Electrochemical Detection of Picomolar Platelet-Derived Growth Factor Directly in Blood Serum

    Rebecca Y. Lai;Kevin W. Plaxco;Alan J. Heeger

  • Real-time measurement of small molecules directly in awake, ambulatory animals

    Netzahualcóyotl Arroyo-Currás;Jacob Somerson;Philip A. Vieira;Kyle L. Ploense

  • High-Efficiency Fluorescence Quenching of Conjugated Polymers by Proteins

    Chunhai Fan;Kevin W. Plaxco;Alan J. Heeger

Frequent Co-Authors

Francesco Ricci
Francesco Ricci University of Rome Tor Vergata
Alan J. Heeger
Alan J. Heeger University of California, Santa Barbara
Fan Xia
Fan Xia China University of Geosciences
H. Tom Soh
H. Tom Soh Stanford University
Tobin R. Sosnick
Tobin R. Sosnick University of Chicago
Ingo Ruczinski
Ingo Ruczinski Johns Hopkins University
Xiaolei Zuo
Xiaolei Zuo Shanghai Jiao Tong University
David Baker
David Baker University of Washington
Chunhai Fan
Chunhai Fan Chinese Academy of Sciences
Christopher M. Dobson
Christopher M. Dobson University of Cambridge

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