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D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
16855
World Ranking
8180
National Ranking
3697

Overview

Tobin R. Sosnick is affiliated with the University of Chicago in the United States. Their research predominantly lies in the field of Biochemistry, Genetics and Molecular Biology, with a strong focus on Molecular Biology and its related subfields including Atomic and Molecular Physics, and Optics, Spectroscopy, Materials Chemistry, and Biophysics.

Their work explores a range of complex topics within the life sciences, including Protein Structure and Dynamics, RNA and protein synthesis mechanisms, Enzyme Structure and Function, RNA Research and Splicing, Mass Spectrometry Techniques and Applications, Spectroscopy and Quantum Chemical Studies, as well as Photoreceptor and optogenetics research.

Among the recent publications attributed to Tobin R. Sosnick are:

  • Protein folds vs. protein folding: Differing questions, different challenges (2022) in Proceedings of the National Academy of Sciences
  • Structural basis for adhesion G protein-coupled receptor Gpr126 function (2020) in Nature Communications
  • Properties of protein unfolded states suggest broad selection for expanded conformational ensembles (2020) in Proceedings of the National Academy of Sciences
  • Water as a Good Solvent for Unfolded Proteins: Folding and Collapse are Fundamentally Different (2020) in Journal of Molecular Biology
  • HDX-MS performed on BtuB in E. coli outer membranes delineates the luminal domain's allostery and unfolding upon B12 and TonB binding (2022) in Proceedings of the National Academy of Sciences

Tobin R. Sosnick has frequently published in several prominent scientific venues. These include:

  • Biophysical Journal (26 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (10 publications)
  • Proceedings of the National Academy of Sciences (7 publications)
  • Nature Communications (2 publications)
  • Journal of Chemical Theory and Computation (2 publications)

The scientist has collaborated extensively with a number of co-authors. Frequent collaborators include Michael C. Baxa, Nabil F. Faruk, Xiangda Peng, Isabelle A. Gagnon, and Xiaoxuan Lin.

Best Publications

  • Protein Folding Intermediates: Native-State Hydrogen Exchange

    Yawen Bai;T. R. Sosnick;L. Mayne;S. W. Englander

  • Random-coil behavior and the dimensions of chemically unfolded proteins

    Jonathan E. Kohn;Ian S. Millett;Jaby Jacob;Jaby Jacob;Bojan Zagrovic

  • Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response.

    Joshua A. Riback;Christopher D. Katanski;Jamie L. Kear-Scott;Evgeny V. Pilipenko

  • The barriers in protein folding

    T.R. Sosnick;L. Mayne;R. Hiller;S.W. Englander

  • TULIPs: Tunable, light-controlled interacting protein tags for cell biology

    Devin Strickland;Yuan Lin;Elizabeth Wagner;C Matthew Hope

  • Mechanisms and uses of hydrogen exchange

    S Walter Englander;Tobin R Sosnick;Joan J Englander;Leland Mayne

  • Hydrogen exchange: The modern legacy of Linderstrøm-Lang

    S. W. Englander;L. Mayne;Y. Bai;T. R. Sosnick

  • Light-activated DNA binding in a designed allosteric protein.

    Devin Strickland;Keith Moffat;Tobin R. Sosnick

  • Statistical coil model of the unfolded state: Resolving the reconciliation problem

    Abhishek K. Jha;Andrés Colubri;Karl F. Freed;Tobin R. Sosnick

  • Molecular collapse: the rate-limiting step in two-state cytochrome c folding

    Tobin R. Sosnick;Leland Mayne;S. Water Englander

  • RNA FOLDING DURING TRANSCRIPTION

    Tao Pan;Tobin Sosnick

  • Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins.

    Karen L. Maxwell;David Wildes;Arash Zarrine-Afsar;Miguel A. De Los Rios

  • Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water

    Joshua A. Riback;Micayla A. Bowman;Adam M. Zmyslowski;Catherine R. Knoverek

  • Intermediates and kinetic traps in the folding of a large ribozyme revealed by circular dichroism and UV absorbance spectroscopies and catalytic activity.

    Tao Pan;Tobin R. Sosnick

  • Denatured states of ribonuclease A have compact dimensions and residual secondary structure.

    Sosnick Tr;Trewhella J

  • Rationally improving LOV domain-based photoswitches

    Devin Strickland;Xiaolan Yao;Grzegorz Gawlak;Michael K Rosen

  • Trifluoroethanol Promotes Helix Formation by Destabilizing Backbone Exposure: Desolvation Rather than Native Hydrogen Bonding Defines the Kinetic Pathway of Dimeric Coiled Coil Folding†

    Alex Kentsis;Tobin R. Sosnick

  • Helix, sheet, and polyproline II frequencies and strong nearest neighbor effects in a restricted coil library.

    Abhishek K. Jha;Andres Colubri;Muhammad H. Zaman;Shohei Koide

  • Ultrafast signals in protein folding and the polypeptide contracted state

    T. R. Sosnick;M. D. Shtilerman;L. Mayne;S. W. Englander

  • RESEARCH ARTICLES Molecular Collapse: The Rate-Limiting Step in Two-State Cytochrome c Folding

    Tobin R. Sosnick;Leland Mayne;S. Walter Englander

Frequent Co-Authors

Karl F. Freed
Karl F. Freed University of Chicago
Tao Pan
Tao Pan Jinan University
Kevin W. Plaxco
Kevin W. Plaxco University of California, Santa Barbara
S. Walter Englander
S. Walter Englander University of Pennsylvania
Pappannan Thiyagarajan
Pappannan Thiyagarajan Argonne National Laboratory
Benoît Roux
Benoît Roux University of Chicago
Jill Trewhella
Jill Trewhella University of Sydney
R. Stephen Berry
R. Stephen Berry University of Chicago
Jinbo Xu
Jinbo Xu Toyota Technological Institute at Chicago
Ingo Ruczinski
Ingo Ruczinski Johns Hopkins University

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