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D-Index & Metrics

Chemistry

D-Index
82
Citations
28181
World Ranking
3052
National Ranking
1016

Overview

Robert B. Best is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with 129 publications in this area. Within these broad fields, they have contributed notably to subfields including Molecular Biology, Atomic and Molecular Physics and Optics, Materials Chemistry, Spectroscopy, and Genetics.

The scientist's work covers several main topics, with a significant number of publications addressing Protein Structure and Dynamics, RNA Research and Splicing, RNA and protein synthesis mechanisms, Enzyme Structure and Function, Force Microscopy Techniques and Applications, Spectroscopy and Quantum Chemical Studies, and Lipid metabolism and biosynthesis.

Frequent collaborators of Robert B. Best include Benjamin Schuler, Daniel Nettels, Miloš T. Ivanović, Andrea Sottini, and Aritra Chowdhury.

They have published extensively in several scientific venues. The most frequent publication outlets include:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Nature Communications
  • Proceedings of the National Academy of Sciences

Selected recent papers include:

  • Martini 3: a general purpose force field for coarse-grained molecular dynamics, 2021, Nature Methods
  • Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties, 2020, Annual Review of Physical Chemistry
  • Extreme dynamics in a biomolecular condensate, 2023, Nature
  • Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations, 2020, The Journal of Physical Chemistry B
  • A Data-Driven Hydrophobicity Scale for Predicting Liquid-Liquid Phase Separation of Proteins, 2021, The Journal of Physical Chemistry B

Best Publications

  • Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone φ, ψ and side-chain χ(1) and χ(2) dihedral angles.

    Robert B. Best;Xiao Zhu;Jihyun Shim;Pedro E. M. Lopes

  • Martini 3 : A general purpose force field for coarse-grained molecular dynamics

    Paulo C. T. Souza;Paulo C. T. Souza;Riccardo Alessandri;Jonathan Barnoud;Jonathan Barnoud;Sebastian Thallmair;Sebastian Thallmair

  • Optimized molecular dynamics force fields applied to the helix-coil transition of polypeptides.

    Robert B. Best;Gerhard Hummer

  • Simultaneous determination of protein structure and dynamics

    Kresten Lindorff-Larsen;Kresten Lindorff-Larsen;Robert B. Best;Robert B. Best;Mark A. DePristo;Mark A. DePristo;Christopher M. Dobson

  • Polarizable Atomic Multipole-Based AMOEBA Force Field for Proteins

    Yue Shi;Zhen Xia;Jiajing Zhang;Robert Best

  • Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

    Robert B. Best;Wenwei Zheng;Jeetain Mittal

  • Sequence determinants of protein phase behavior from a coarse-grained model.

    Gregory L. Dignon;Wenwei Zheng;Young C. Kim;Robert B. Best

  • Extreme disorder in an ultrahigh-affinity protein complex

    Alessandro Borgia;Madeleine B. Borgia;Katrine Østergaard Bugge;Vera M. Kissling

  • Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity

    Zachary Monahan;Veronica H Ryan;Abigail M Janke;Kathleen A Burke

  • Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties

    Gregory L. Dignon;Gregory L. Dignon;Robert B. Best;Jeetain Mittal

  • Native contacts determine protein folding mechanisms in atomistic simulations

    Robert B. Best;Gerhard Hummer;William A. Eaton

  • Are Current Molecular Dynamics Force Fields too Helical

    Robert B. Best;Nicolae-Viorel Buchete;Gerhard Hummer

  • Reaction coordinates and rates from transition paths

    Robert B. Best;Gerhard Hummer

  • Relation between single-molecule properties and phase behavior of intrinsically disordered proteins

    Gregory L. Dignon;Wenwei Zheng;Robert B. Best;Young C. Kim

  • Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations.

    Kusai A. Merchant;Robert B. Best;John M. Louis;Irina V. Gopich

  • Coordinate-dependent diffusion in protein folding.

    Robert B. Best;Gerhard Hummer

  • Hidden complexity in the mechanical properties of titin

    Philip M. Williams;Susan B. Fowler;Robert B. Best;José Luis Toca-Herrera;José Luis Toca-Herrera

  • Protein simulations with an optimized water model: cooperative helix formation and temperature-induced unfolded state collapse.

    Robert B. Best;Jeetain Mittal

  • Computational and theoretical advances in studies of intrinsically disordered proteins.

    Robert B Best

  • Can Non-Mechanical Proteins Withstand Force? Stretching Barnase by Atomic Force Microscopy and Molecular Dynamics Simulation

    Robert B. Best;Bin Li;Annette Steward;Valerie Daggett

  • Correction to Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

    Robert B. Best;Wenwei Zheng;Jeetain Mittal

Frequent Co-Authors

Jeetain Mittal
Jeetain Mittal Lehigh University
Benjamin Schuler
Benjamin Schuler University of Zurich
Jane Clarke
Jane Clarke University of Cambridge
Gerhard Hummer
Gerhard Hummer Max Planck Society
Gunnar von Heijne
Gunnar von Heijne Stockholm University
Kresten Lindorff-Larsen
Kresten Lindorff-Larsen University of Copenhagen
John M. Louis
John M. Louis National Institutes of Health
Michele Vendruscolo
Michele Vendruscolo University of Cambridge
Jochen Blumberger
Jochen Blumberger University College London
Michal Otyepka
Michal Otyepka Palacký University, Olomouc

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