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Chemistry

D-Index
63
Citations
20513
World Ranking
8276
National Ranking
2395

Research.com Recognitions

  • 2014 - Fellow of Alfred P. Sloan Foundation

Overview

Jeetain Mittal is affiliated with Lehigh University in the United States and primarily conducts research in the field of Biochemistry, Genetics and Molecular Biology. Their work focuses heavily on Molecular Biology, with additional contributions in Materials Chemistry, Biomedical Engineering, Neurology, and Biochemistry.

Mittal's research interests encompass a range of topics related to RNA and protein biology, including:

  • RNA Research and Splicing
  • Protein Structure and Dynamics
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Amyotrophic Lateral Sclerosis Research
  • Enzyme Structure and Function

They have published extensively across multiple venues, with a notable frequency in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • The Journal of Physical Chemistry B
  • Proceedings of the National Academy of Sciences
  • Journal of Biological Chemistry

Frequent collaborators include Young C. Kim, Priyesh Mohanty, Tien M. Phan, Nicolas L. Fawzi, and Azamat Rizuan, indicating a network of ongoing research partnerships.

Selected recent papers by Jeetain Mittal illustrate the focus and scope of their work:

  • Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties (2020), published in Annual Review of Physical Chemistry
  • TDP-43 α-helical structure tunes liquid-liquid phase separation and function (2020), published in Proceedings of the National Academy of Sciences
  • Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior (2020), published in Proceedings of the National Academy of Sciences
  • Improved coarse-grained model for studying sequence dependent phase separation of disordered proteins (2021), published in Protein Science
  • Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations (2020), published in The Journal of Physical Chemistry B

In 2014, Mittal was recognized as a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone φ, ψ and side-chain χ(1) and χ(2) dihedral angles.

    Robert B. Best;Xiao Zhu;Jihyun Shim;Pedro E. M. Lopes

  • ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.

    Alexander E. Conicella;Gül H. Zerze;Jeetain Mittal;Nicolas L. Fawzi

  • Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain

    Anastasia C. Murthy;Gregory L. Dignon;Yelena Kan;Yelena Kan;Gül H. Zerze;Gül H. Zerze

  • Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

    Robert B. Best;Wenwei Zheng;Jeetain Mittal

  • Sequence determinants of protein phase behavior from a coarse-grained model.

    Gregory L. Dignon;Wenwei Zheng;Young C. Kim;Robert B. Best

  • Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity

    Zachary Monahan;Veronica H Ryan;Abigail M Janke;Kathleen A Burke

  • Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties

    Gregory L. Dignon;Gregory L. Dignon;Robert B. Best;Jeetain Mittal

  • Relation between single-molecule properties and phase behavior of intrinsically disordered proteins

    Gregory L. Dignon;Wenwei Zheng;Robert B. Best;Young C. Kim

  • TDP-43 α-helical structure tunes liquid–liquid phase separation and function

    Alexander E. Conicella;Gregory L. Dignon;Gül H. Zerze;Gül H. Zerze;Hermann Broder Schmidt

  • Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior

    Benjamin S. Schuster;Gregory L. Dignon;Gregory L. Dignon;Wai Shing Tang;Fleurie M. Kelley

  • Temperature-Controlled Liquid-Liquid Phase Separation of Disordered Proteins

    Gregory L. Dignon;Wenwei Zheng;Young C. Kim;Jeetain Mittal

  • Protein simulations with an optimized water model: cooperative helix formation and temperature-induced unfolded state collapse.

    Robert B. Best;Jeetain Mittal

  • Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations.

    Wenwei Zheng;Gregory L. Dignon;Nina Jovic;Xichen Xu

  • A Carbon Nanotube Reporter of miRNA Hybridization Events In Vivo.

    Jackson D. Harvey;Prakrit V. Jena;Hanan A. Baker;Hanan A. Baker;Gül H. Zerze

  • Layering and position-dependent diffusive dynamics of confined fluids

    Jeetain Mittal;Thomas M. Truskett;Jeffrey R. Errington;Gerhard Hummer

  • Temperature-dependent solvation modulates the dimensions of disordered proteins

    René Wuttke;Hagen Hofmann;Daniel Nettels;Madeleine B. Borgia

  • Thermodynamics and kinetics of protein folding under confinement

    Jeetain Mittal;Robert B. Best

  • Excess-entropy-based anomalies for a waterlike fluid.

    Jeffrey R. Errington;Thomas M. Truskett;Jeetain Mittal

  • Inclusion of Many-Body Effects in the Additive CHARMM Protein CMAP Potential Results in Enhanced Cooperativity of α-Helix and β-Hairpin Formation

    Robert B. Best;Jeetain Mittal;Michael Feig;Alexander D. MacKerell

  • Thermodynamics predicts how confinement modifies the dynamics of the equilibrium hard-sphere fluid.

    Jeetain Mittal;Jeffrey R. Errington;Thomas M. Truskett

  • Correction to Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

    Robert B. Best;Wenwei Zheng;Jeetain Mittal

Frequent Co-Authors

Robert B. Best
Robert B. Best National Institutes of Health
Thomas M. Truskett
Thomas M. Truskett The University of Texas at Austin
Jeffrey R. Errington
Jeffrey R. Errington University at Buffalo, State University of New York
Daniel A. Heller
Daniel A. Heller Memorial Sloan Kettering Cancer Center
Anand Jagota
Anand Jagota Lehigh University
Mark Snyder
Mark Snyder University of Minnesota
Gerhard Hummer
Gerhard Hummer Max Planck Society
Johanna A. Joyce
Johanna A. Joyce Ludwig Cancer Research
Venkat Ganesan
Venkat Ganesan The University of Texas at Austin
Ashutosh Sharma
Ashutosh Sharma Indian Institute of Technology Kanpur

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