His main research concerns Chromatography, Solubility, Partition coefficient, Membrane and Inorganic chemistry. His Chromatography study combines topics in areas such as Intestinal absorption, Synthetic membrane and Membrane permeability. Alex Avdeef has researched Solubility in several fields, including Potentiometric titration, Dissolution and Thermodynamics.
Alex Avdeef has included themes like Ionic strength, Lipophilicity, Analytical chemistry and Acid dissociation constant in his Partition coefficient study. His Membrane research incorporates themes from Biophysics, Transcellular and Drug. His research in Inorganic chemistry intersects with topics in Stability constants of complexes and Aqueous solution.
Alex Avdeef mainly investigates Chromatography, Solubility, Inorganic chemistry, Aqueous solution and Analytical chemistry. His Chromatography research includes elements of Intestinal absorption and Membrane, Synthetic membrane, Membrane permeability. The various areas that Alex Avdeef examines in his Solubility study include Solvation, Molecule, Thermodynamics and Dissolution.
His work in the fields of Inorganic chemistry, such as Titration and Ferric, intersects with other areas such as Glass electrode. His Aqueous solution research incorporates elements of Electroanalytical method, Cadmium and Nuclear chemistry. Alex Avdeef has researched Partition coefficient in several fields, including Ionic strength, Lipophilicity and Acid dissociation constant.
Alex Avdeef mostly deals with Solubility, Solubility equilibrium, Chromatography, Aqueous solution and Cocrystal. His Solubility study combines topics from a wide range of disciplines, such as Solvation and Henderson–Hasselbalch equation, Supersaturation, Thermodynamics. His Thermodynamics research includes elements of Partition coefficient and Molecule.
Alex Avdeef combines subjects such as Ionic strength and Equilibrium constant with his study of Solubility equilibrium. His research brings together the fields of Amitriptyline and Chromatography. His work carried out in the field of Aqueous solution brings together such families of science as Intestinal absorption, Sodium dodecyl sulfate and Weak base.
His primary scientific interests are in Solubility, Chromatography, Dissolution, Organic chemistry and Solubility equilibrium. His Solubility study integrates concerns from other disciplines, such as Potentiometric titration, Data set and Phenothiazine. His studies in Chromatography integrate themes in fields like Decomposition, Molding and Octane.
His Dissolution research is multidisciplinary, incorporating elements of Computational chemistry, Equilibrium constant, Active ingredient and Incubation. His work on Organic chemistry deals in particular with Ionic strength, Aqueous solution, Molar solubility, Henderson–Hasselbalch equation and Micelle. The concepts of his Solubility equilibrium study are interwoven with issues in Cocrystal and Hildebrand solubility parameter.
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Absorption and Drug Development: Solubility, Permeability, and Charge State
Physicochemical Profiling (Solubility, Permeability and Charge State)
Current Topics in Medicinal Chemistry (2001)
Coexistence of passive and carrier-mediated processes in drug transport
Kiyohiko Sugano;Manfred Kansy;Per Artursson;Alex Avdeef.
Nature Reviews Drug Discovery (2010)
pH-metric logP 10. Determination of liposomal membrane-water partition coefficients of ionizable drugs.
A. Avdeef;K. J. Box;J. E. A. Comer;C. Hibbert.
Pharmaceutical Research (1998)
Coordination chemistry of microbial iron transport compounds. 9. Stability constants for catechol models of enterobactin
Alex Avdeef;Stephen R. Sofen;Thomas L. Bregante;Kenneth N. Raymond.
Coordination chemistry of microbial iron transport compounds. 19. Stability constants and electrochemical behavior of ferric enterobactin and model complexes
Wesley R. Harris;Carl J. Carrano;Stephen R. Cooper;Stephen R. Sofen.
Journal of the American Chemical Society (1979)
pH-metric solubility. 2: correlation between the acid-base titration and the saturation shake-flask solubility-pH methods.
Alex Avdeef;Cynthia M. Berger;Charles Brownell.
Pharmaceutical Research (2000)
Absorption Classification of Oral Drugs Based on Molecular Surface Properties
Christel A S Bergström;Melissa Strafford;Lucia Lazorova;Alex Avdeef.
Journal of Medicinal Chemistry (2003)
Solubility of sparingly-soluble ionizable drugs.
Advanced Drug Delivery Reviews (2007)
PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent-water mixtures.
A Avdeef;K.J Box;J.E.A Comer;M Gilges.
Journal of Pharmaceutical and Biomedical Analysis (1999)
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