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Chemistry

D-Index
103
Citations
43205
World Ranking
1099
National Ranking
440

Overview

Gordon L. Amidon is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on the intersection of medicine and pharmacology, toxicology, and pharmaceutics, with a particular emphasis on pharmaceutical science and gastrointestinal studies.

The scientist has contributed notably to the study of drug solubility and delivery systems, gastrointestinal motility and disorders, and various analytical and biochemical techniques related to pharmaceutical sciences. Other main topics in their work include analytical chemistry and chromatography, analytical methods in pharmaceuticals, crystallization and solubility studies, protein purification and stability, and drug transport and resistance mechanisms.

Frequent co-authors in their publications include Bart Hens, Gregory E. Amidon, Marival Bermejo, Niloufar Salehi, and Jozef Al-Gousous.

Gordon L. Amidon's work has appeared frequently in the following publication venues:

  • Molecular Pharmaceutics
  • Pharmaceutics
  • European Journal of Pharmaceutical Sciences
  • Pharmaceutical Research
  • PLoS ONE

Recent papers authored by or involving Gordon L. Amidon include:

  • A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP, 2020, Pharmaceutics
  • Hierarchical Mass Transfer Analysis of Drug Particle Dissolution, Highlighting the Hydrodynamics, pH, Particle Size, and Buffer Effects for the Dissolution of Ionizable and Nonionizable Drugs in a Compendial Dissolution Vessel, 2020, Molecular Pharmaceutics
  • Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications, 2020, European Journal of Pharmaceutical Sciences
  • Improving Dissolution Behavior and Oral Absorption of Drugs with pH-Dependent Solubility Using pH Modifiers: A Physiologically Realistic Mass Transport Analysis, 2021, Molecular Pharmaceutics
  • Biphasic Dissolution as an Exploratory Method during Early Drug Product Development, 2020, Pharmaceutics

Best Publications

  • A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

    Gordon L. Amidon;Hans Lennernäs;Vinod P. Shah;John R. Crison

  • The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent.

    Manisha P. Desai;Vinod D Labhasetwar;Elke Walter;Robert J. Levy

  • Molecular Properties of WHO Essential Drugs and Provisional Biopharmaceutical Classification

    Nehal A. Kasim;Marc Whitehouse;Chandrasekharan Ramachandran;Marival Bermejo

  • Chemical stability of pharmaceuticals : a handbook for pharmacists

    Kenneth A. Connors;Gordon L. Amidon;Valentino J. Stella

  • Biopharmaceutics Classification System: The Scientific Basis for Biowaiver Extensions

    Lawrence X. Yu;Gordon L. Amidon;James E. Polli;Hong Zhao

  • Lessons learned from marketed and investigational prodrugs

    Peter Ettmayer;Gordon L. Amidon;Bernd Clement;Bernard Testa

  • A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals

    Marilyn N. Martinez;Gordon L. Amidon

  • A provisional biopharmaceutical classification of the top 200 oral drug products in the United States, Great Britain, Spain, and Japan.

    Unknown

  • Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles.

    Jayanth Panyam;Manisha M. Dali;Sanjeeb K. Sahoo;Wenxue Ma

  • Caco-2 versus Caco-2/HT29-MTX Co-cultured Cell Lines: Permeabilities Via Diffusion, Inside- and Outside-Directed Carrier-Mediated Transport

    Constanze Hilgendorf;Hildegard Spahn‐Langguth;Carl G. Regårdh;Elke Lipka

  • A compartmental absorption and transit model for estimating oral drug absorption.

    Lawrence X. Yu;Gordon L. Amidon

  • Physiological Parameters for Oral Delivery and in Vitro Testing

    Deanna M. Mudie;Gordon L. Amidon;Gregory E. Amidon

  • Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs.

    Duxin Sun;Hans Lennernas;Lynda S. Welage;Jeffery L. Barnett

  • Quantification of Gastrointestinal Liquid Volumes and Distribution Following a 240 mL Dose of Water in the Fasted State

    Deanna M. Mudie;Kathryn Murray;Caroline L. Hoad;Susan E. Pritchard

  • Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption.

    Lawrence X. Yu;Elke Lipka;John R. Crison;Gordon L. Amidon

  • Thermodynamic studies on the gel-sol transition of some pluronic polyols

    Madhu Vadnere;Gordon Amidon;Siegfried Lindenbaum;John L. Haslam

  • Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.

    Xianhua Cao;Seth T. Gibbs;Lanyan Fang;Heather A. Miller

  • 5′-Amino Acid Esters of Antiviral Nucleosides, Acyclovir, and AZT Are Absorbed by the Intestinal PEPT1 Peptide Transporter

    Hyo Kyung Han;Remco L.A. De Vrueh;Julie K. Rhie;Kuang Ming Y. Covitz

  • Estimating Human Oral Fraction Dose Absorbed: A Correlation Using Rat Intestinal Membrane Permeability for Passive and Carrier-Mediated Compounds

    Gordon L. Amidon;Patrick J. Sinko;David Fleisher

  • The Biopharmaceutics Classification System: subclasses for in vivo predictive dissolution (IPD) methodology and IVIVC

    Yasuhiro Tsume;Deanna M. Mudie;Peter Langguth;Greg E. Amidon

  • Chemical stability of pharmaceuticals

    Kenneth A. Connors;Gordon L. Amidon;Valentino J. Stella

Frequent Co-Authors

Duxin Sun
Duxin Sun University of Michigan–Ann Arbor
Hans Lennernäs
Hans Lennernäs Uppsala University
Lawrence J. Lesko
Lawrence J. Lesko University of Florida
Wolfgang Sadee
Wolfgang Sadee The Ohio State University
Patrick J. Sinko
Patrick J. Sinko Rutgers, The State University of New Jersey
Robert J. Levy
Robert J. Levy Children's Hospital of Philadelphia
Leslie Z. Benet
Leslie Z. Benet University of California, San Francisco
Naír Rodríguez-Hornedo
Naír Rodríguez-Hornedo University of Michigan–Ann Arbor
Beverly L. Davidson
Beverly L. Davidson Children's Hospital of Philadelphia
Hitoshi Sezaki
Hitoshi Sezaki Kyoto University

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