Hitoshi Sezaki focuses on Pharmacokinetics, Pharmacology, Dextran, Biochemistry and Chromatography. The various areas that he examines in his Pharmacokinetics study include Cerebrospinal fluid, Nasal cavity, Targeted drug delivery, Endocytosis and Distribution. His work carried out in the field of Pharmacology brings together such families of science as Perfusion, Permeation and Pathology.
While working in this field, he studies both Dextran and Conjugate. His Biochemistry research incorporates themes from Biophysics and Sulfaguanidine. His research integrates issues of Small intestine, Intestinal mucosa, Intestinal absorption, Membrane permeability and Organic chemistry in his study of Chromatography.
Hitoshi Sezaki mainly investigates Chromatography, Biochemistry, Intestinal absorption, Pharmacology and Pharmacokinetics. His biological study spans a wide range of topics, including Liposome, Absorption, Emulsion, Membrane and Aqueous solution. Hitoshi Sezaki has researched Biochemistry in several fields, including Absorption and Biophysics.
His Intestinal absorption research includes themes of Salicylic acid, Small intestine and Phenol red. His work deals with themes such as Mitomycin C, Gastrointestinal tract and Perfusion, which intersect with Pharmacology. His research investigates the link between Pharmacokinetics and topics such as Nasal cavity that cross with problems in Cerebrospinal fluid.
The scientist’s investigation covers issues in Pharmacology, Intestinal absorption, Pharmacokinetics, Chromatography and Biochemistry. The concepts of his Pharmacology study are interwoven with issues in Mitomycin C, Phenol red and Pathology. The Intestinal absorption study combines topics in areas such as Absorption, Ileum, Small intestine and Permeability.
His Pharmacokinetics research integrates issues from Endocrinology, Drug and Nasal cavity. He interconnects Whole blood, Salicylic acid, Lipophilicity, Saline and Membrane permeability in the investigation of issues within Chromatography. His Biochemistry study integrates concerns from other disciplines, such as Scientific method and Biophysics.
Hitoshi Sezaki mainly focuses on Pharmacokinetics, Pharmacology, Chromatography, Intestinal absorption and Cerebrospinal fluid. His biological study spans a wide range of topics, including Whole blood, Stratum corneum and Incubation. His research in the fields of Oral administration and Drug overlaps with other disciplines such as Conjugate.
His work carried out in the field of Chromatography brings together such families of science as Kidney and Saline. His research in Intestinal absorption intersects with topics in Fetal bovine serum, Lipophilicity, Pulmonary surfactant, Membrane permeability and Cholic acid. His studies in Cerebrospinal fluid integrate themes in fields like Anesthesia, Nasal administration, Nose and Nasal cavity.
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Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells.
Shinji Yamashita;Tomoyuki Furubayashi;Makoto Kataoka;Toshiyasu Sakane.
European Journal of Pharmaceutical Sciences (2000)
Disposition and Tumor Localization of Mitomycin C–Dextran Conjugates in Mice
Yoshinobu Takakura;Akira Takagi;Mitsuru Hashida;Hitoshi Sezaki.
Pharmaceutical Research (1987)
Transport of cephalexin to the cerebrospinal fluid directly from the nasal cavity.
Toshiyasu Sakane;Motohiro Akizuki;Masako Yoshida;Shinji Yamashita.
Journal of Pharmacy and Pharmacology (2011)
The transport of a drug to the cerebrospinal fluid directly from the nasal cavity: the relation to the lipophilicity of the drug.
Toshiyasu Sakane;Motohiro Akizuki;Shinji Yamashita;Tanekazu Nadai.
Chemical & Pharmaceutical Bulletin (1991)
In Vitro System to Evaluate Oral Absorption of Poorly Water-Soluble Drugs: Simultaneous Analysis on Dissolution and Permeation of Drugs
Makoto Kataoka;Yoshie Masaoka;Yukako Yamazaki;Toshiyasu Sakane.
Pharmaceutical Research (2003)
Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and polysaccharide derivatives.
T. Fujita;Makiya Nishikawa;C. Tamaki;Y. Takakura.
Journal of Pharmacology and Experimental Therapeutics (1992)
Analysis of Drug Permeation Across Caco-2 Monolayer: Implication for Predicting In Vivo Drug Absorption
Shinji Yamashita;Yoshihiro Tanaka;Yoriko Endoh;Yoko Taki.
Pharmaceutical Research (1997)
New and better protocols for a short-term Caco-2 cell culture system
Shinji Yamashita;Keisuke Konishi;Yukako Yamazaki;Yoko Taki.
Journal of Pharmaceutical Sciences (2002)
Structure–Activity Relationship of 1-Alkyl- or 1 -Alkenylazacycloal kanone Derivatives as Percutaneous Penetration Enhancers
Hirokazu Okamoto;Mitsuru Hashida;Hitoshi Sezaki.
Journal of Pharmaceutical Sciences (1988)
Mitomycin C-dextran conjugate: a novel high molecular weight pro-drug of mitomycin C
T Kojima;M Hashida;S Muranishi;H Sezaki.
Journal of Pharmacy and Pharmacology (2011)
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