World's Best Scientists 2026 revealed!
Shigeru Kawakami

Shigeru Kawakami

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
10190
World Ranking
12761
National Ranking
879

Shigeru Kawakami publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Shigeru Kawakami sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 220 publications — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Shigeru Kawakami D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Shigeru Kawakami sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 59 D-Index — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Shigeru Kawakami is affiliated with Nagasaki University in Japan and has contributed extensively to the field of biochemistry, genetics, and molecular biology, with a focus on RNA interference and gene delivery. Their research spans molecular biology, genetics, biomedical engineering, immunology, and biomaterials.

Kawakami's recent publications demonstrate a concentration on lipid nanoparticles (LNPs) and mRNA delivery technologies. Notable papers include:

  • Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain, 2022, Journal of Controlled Release
  • Recent advances in lipid nanoparticles for delivery of nucleic acid, mRNA, and gene editing-based therapeutics, 2022, Drug Metabolism and Pharmacokinetics
  • Stability Study of mRNA-Lipid Nanoparticles Exposed to Various Conditions Based on the Evaluation between Physicochemical Properties and Their Relation with Protein Expression Ability, 2022, Pharmaceutics
  • Effect of Cholesterol Content of Lipid Composition in mRNA-LNPs on the Protein Expression in the Injected Site and Liver After Local Administration in Mice, 2022, Journal of Pharmaceutical Sciences
  • A turn-on hydrazide oxidative decomposition-based fluorescence probe for highly selective detection of Cu2+ in tap water as well as cell imaging, 2022, Analytica Chimica Acta

The primary research topics covered in Kawakami's work include:

  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Nanoparticle-Based Drug Delivery
  • Virus-based gene therapy research
  • Immunotherapy and Immune Responses
  • Extracellular vesicles in disease
  • Renal and related cancers

Frequent collaborators in Kawakami's research include Hidefumi Mukai, Naoya Kato, Mariko Kamiya, Koki Ogawa, and Maho Kawaguchi.

Kawakami's work has been published primarily in these venues:

  • Pharmaceutics
  • Journal of Pharmaceutical Sciences
  • Drug Delivery
  • Journal of Controlled Release
  • Drug Metabolism and Pharmacokinetics

Their research contributions examine the molecular and physicochemical characteristics of mRNA-lipid nanoparticles and their implications for protein expression and delivery efficacy. This includes investigations into lipid composition, stability under various conditions, and targeted delivery to organs such as the brain and liver.

Best Publications

  • Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes

    S. Kawakami;A. Sato;Makiya Nishikawa;F. Yamashita

  • Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting.

    Takeshi Terada;Mieko Iwai;Shigeru Kawakami;Fumiyoshi Yamashita

  • In vivo gene delivery to the liver using novel galactosylated cationic liposomes.

    Shigeru Kawakami;Shintaro Fumoto;Makiya Nishikawa;Fumiyoshi Yamashita

  • Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver

    Kensuke Morimoto;Makiya Nishikawa;Shigeru Kawakami;Takayuki Nakano

  • Asialoglycoprotein Receptor-Mediated Gene Transfer Using Novel Galactosylated Cationic Liposomes

    Shigeru Kawakami;Fumiyoshi Yamashita;Makiya Nishikawa;Yoshinobu Takakura

  • Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats

    Wassana Wijagkanalan;Shigeru Kawakami;Mitsuko Takenaga;Rie Igarashi

  • Efficient Gene Transfection by Histidine-Modified Chitosan through Enhancement of Endosomal Escape

    Kai-Ling Chang;Yuriko Higuchi;Shigeru Kawakami;Fumiyoshi Yamashita

  • Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice.

    Ayumi Sato;Motoki Takagi;Akira Shimamoto;Shigeru Kawakami

  • Nonviral approaches for targeted delivery of plasmid DNA and oligonucleotide

    Shigeru Kawakami;Yuriko Higuchi;Mitsuru Hashida

  • Designing Dendrimers for Drug Delivery and Imaging: Pharmacokinetic Considerations

    Wassana Wijagkanalan;Wassana Wijagkanalan;Shigeru Kawakami;Mitsuru Hashida

  • Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice.

    Shigeru Kawakami;Joseph Wong;Ayumi Sato;Yoshiyuki Hattori

  • Strategies for in vivo delivery of siRNAs: recent progress.

    Yuriko Higuchi;Shigeru Kawakami;Mitsuru Hashida

  • PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice.

    Tatsuya Okuda;Shigeru Kawakami;Naomi Akimoto;Takuro Niidome

  • Targeted Delivery Systems of Small Interfering RNA by Systemic Administration

    Shigeru Kawakami;Mitsuru Hashida

  • Enhancement of immune responses by DNA vaccination through targeted gene delivery using mannosylated cationic liposome formulations following intravenous administration in mice.

    Yoshiyuki Hattori;Shigeru Kawakami;Sachiko Suzuki;Fumiyoshi Yamashita

  • Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration.

    Tatsuya Okuda;Shigeru Kawakami;Tadahiro Maeie;Takuro Niidome

  • Photothermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite.

    Yasuhiko Hashida;Hironori Tanaka;Shuwen Zhou;Shigeru Kawakami

  • Evaluation of Proinflammatory Cytokine Production Induced by Linear and Branched Polyethylenimine/Plasmid DNA Complexes in Mice

    Shigeru Kawakami;Yoshitaka Ito;Pensri Charoensit;Fumiyoshi Yamashita

  • The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route.

    Yoshiyuki Hattori;Sachiko Suzuki;Shigeru Kawakami;Fumiyoshi Yamashita

  • piggyBac transposon-mediated long-term gene expression in mice.

    Hideyuki Nakanishi;Yuriko Higuchi;Shigeru Kawakami;Fumiyoshi Yamashita

Frequent Co-Authors

Mitsuru Hashida
Mitsuru Hashida Kyoto University
Fumiyoshi Yamashita
Fumiyoshi Yamashita Kyoto University
Makiya Nishikawa
Makiya Nishikawa Tokyo University of Science
Makoto Kiso
Makoto Kiso Gifu University
Takuro Niidome
Takuro Niidome Kumamoto University
Yoshiki Katayama
Yoshiki Katayama Kyushu University
Kenichiro Nakashima
Kenichiro Nakashima Nagasaki University
Hideharu Ishida
Hideharu Ishida Gifu University
Tomokazu Umeyama
Tomokazu Umeyama Kyoto University
Takashi Tanaka
Takashi Tanaka Nagasaki University

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