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Molecular Biology

D-Index
72
Citations
17917
World Ranking
1322
National Ranking
107

Overview

Makiya Nishikawa is affiliated with Tokyo University of Science in Japan and has a significant body of research in the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their work spans several key subfields, including Molecular Biology, Biomedical Engineering, Surgery, Genetics, and Immunology.

Their research primarily focuses on a range of topics that include:

  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • DNA and Nucleic Acid Chemistry
  • Mesenchymal stem cell research
  • 3D Printing in Biomedical Research
  • Tissue Engineering and Regenerative Medicine
  • Flavonoids in Medical Research

Makiya Nishikawa has published multiple papers that illustrate this diverse expertise. Some of the recent papers include:

  • Drug Metabolism and Pharmacokinetics of Antisense Oligonucleotide Therapeutics: Typical Profiles, Evaluation Approaches, and Points to Consider Compared with Small Molecule Drugs (2023, Nucleic Acid Therapeutics)
  • Anticancer drug-loaded mesenchymal stem cells for targeted cancer therapy (2020, Journal of Controlled Release)
  • Development of nanoparticles derived from corn as mass producible bionanoparticles with anticancer activity (2021, Scientific Reports)
  • Mesenchymal stem/stromal cells as next-generation drug delivery vehicles for cancer therapeutics (2021, Expert Opinion on Drug Delivery)
  • Intravenous injection of mesenchymal stem cell spheroids improves the pulmonary delivery and prolongs in vivo survival (2021, Biotechnology Journal)

The scientist has frequently published in journals such as:

  • Drug Delivery System
  • Journal of Controlled Release
  • International Journal of Biological Macromolecules
  • Biological and Pharmaceutical Bulletin
  • SSRN Electronic Journal

Collaboration has been a significant component of Nishikawa's research efforts. Frequent co-authors include:

  • Kosuke Kusamori
  • Shoko Itakura
  • Yoshinobu Takakura
  • Yuki Takahashi
  • Yukiya Takayama

Best Publications

  • Nonviral Vectors in the New Millennium: Delivery Barriers in Gene Transfer

    Makiya Nishikawa;Leaf Huang

  • Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection.

    Yuki Takahashi;Makiya Nishikawa;Haruka Shinotsuka;Yuriko Matsui

  • Reactive oxygen species in tumor metastasis.

    Makiya Nishikawa

  • Macrophage-dependent clearance of systemically administered B16BL6-derived exosomes from the blood circulation in mice

    Takafumi Imai;Yuki Takahashi;Makiya Nishikawa;Kana Kato

  • Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes

    S. Kawakami;A. Sato;Makiya Nishikawa;F. Yamashita

  • Exosome-based tumor antigens-adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA.

    Masaki Morishita;Yuki Takahashi;Akihiro Matsumoto;Makiya Nishikawa

  • Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice

    Masaki Morishita;Yuki Takahashi;Makiya Nishikawa;Kohei Sano

  • Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics.

    Chonlada Charoenviriyakul;Yuki Takahashi;Masaki Morishita;Akihiro Matsumoto

  • Cell-specific delivery of genes with glycosylated carriers.

    Mitsuru Hashida;Makiya Nishikawa;Fumiyoshi Yamashita;Yoshinobu Takakura

  • In vivo gene delivery to the liver using novel galactosylated cationic liposomes.

    Shigeru Kawakami;Shintaro Fumoto;Makiya Nishikawa;Fumiyoshi Yamashita

  • Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver

    Kensuke Morimoto;Makiya Nishikawa;Shigeru Kawakami;Takayuki Nakano

  • Biodegradable CpG DNA hydrogels for sustained delivery of doxorubicin and immunostimulatory signals in tumor-bearing mice

    Makiya Nishikawa;Yumiko Mizuno;Kohta Mohri;Nao Matsuoka

  • Catalase delivery for inhibiting ROS-mediated tissue injury and tumor metastasis.

    Makiya Nishikawa;Mitsuru Hashida;Yoshinobu Takakura

  • Pharmacokinetics of Exosomes-An Important Factor for Elucidating the Biological Roles of Exosomes and for the Development of Exosome-Based Therapeutics.

    Masaki Morishita;Yuki Takahashi;Makiya Nishikawa;Yoshinobu Takakura

  • Asialoglycoprotein Receptor-Mediated Gene Transfer Using Novel Galactosylated Cationic Liposomes

    Shigeru Kawakami;Fumiyoshi Yamashita;Makiya Nishikawa;Yoshinobu Takakura

  • Targeted delivery of plasmid DNA complexed with galactosylated poly(L-lysine).

    Mitsuru Hashida;Shigeo Takemura;Makiya Nishikawa;Yoshinobu Takakura

  • Effect of exosome isolation methods on physicochemical properties of exosomes and clearance of exosomes from the blood circulation.

    Takuma Yamashita;Yuki Takahashi;Makiya Nishikawa;Yoshinobu Takakura

  • Preservation of exosomes at room temperature using lyophilization.

    Chonlada Charoenviriyakul;Yuki Takahashi;Makiya Nishikawa;Yoshinobu Takakura

  • Role of Phosphatidylserine-Derived Negative Surface Charges in the Recognition and Uptake of Intravenously Injected B16BL6-Derived Exosomes by Macrophages.

    Akihiro Matsumoto;Yuki Takahashi;Makiya Nishikawa;Kohei Sano

  • DNA nanotechnology-based composite-type gold nanoparticle-immunostimulatory DNA hydrogel for tumor photothermal immunotherapy

    Tomoya Yata;Yuki Takahashi;Mengmeng Tan;Hirotaka Nakatsuji

Frequent Co-Authors

Yoshinobu Takakura
Yoshinobu Takakura Kyoto University
Mitsuru Hashida
Mitsuru Hashida Kyoto University
Fumiyoshi Yamashita
Fumiyoshi Yamashita Kyoto University
Shigeru Kawakami
Shigeru Kawakami Nagasaki University
Hiroshi Sugiyama
Hiroshi Sugiyama Kyoto University
Masayuki Endo
Masayuki Endo Kyoto University
Hitoshi Sezaki
Hitoshi Sezaki Kyoto University
Takuya Fujita
Takuya Fujita Ritsumeikan University
Kuniaki Saito
Kuniaki Saito Fujita Health University
Kazuo Sakurai
Kazuo Sakurai The University of Kitakyushu

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