World's Best Scientists 2026 revealed!
Hidetoshi Arima

Hidetoshi Arima

D-Index & Metrics

Chemistry

D-Index
60
Citations
10975
World Ranking
9857
National Ranking
706

Hidetoshi Arima publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Hidetoshi Arima sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 308 publications — 65th percentile

65% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Hidetoshi Arima D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hidetoshi Arima sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 60 D-Index — 47th percentile

47% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Hidetoshi Arima is affiliated with Kumamoto University in Japan and has a research focus primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their scientific contributions span a diverse set of subfields including Molecular Biology, Physiology, Biomaterials, Organic Chemistry, and Hematology.

Their research addresses several complex topics, notably in Lysosomal Storage Disorders Research, Nanoparticle-Based Drug Delivery, and Carbohydrate Chemistry and Synthesis. Additional important topics covered in their work include RNA Interference and Gene Delivery, Advanced Biosensing and Bioanalysis Techniques, Autoimmune and Inflammatory Disorders Research, and Biocrusts and Microbial Ecology.

Hidetoshi Arima has published multiple papers in several venues, with a particular presence in the International Journal of Molecular Sciences, Life Sciences, Biological and Pharmaceutical Bulletin, YAKUGAKU ZASSHI, and SSRN Electronic Journal.

Recent papers by Hidetoshi Arima include:

  • Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann-Pick Disease Type C Model Mice, 2021, International Journal of Molecular Sciences
  • Lactose-appended β-cyclodextrin as an effective nanocarrier for brain delivery, 2020, Journal of Controlled Release
  • A Mannosylated, PEGylated Albumin as a Drug Delivery System for the Treatment of Cancer Stroma Cells, 2021, Advanced Functional Materials
  • Development of an apolipoprotein E mimetic peptide-lipid conjugate for efficient brain delivery of liposomes, 2023, Drug Delivery
  • Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in Npc1-Null Cells, 2020, International Journal of Molecular Sciences

Frequent collaborators contributing to their body of work include Keiichi Motoyama, Taishi Higashi, Yoichi Ishitsuka, Yusei Yamada, and Katsumi Higaki, each having coauthored multiple publications with Arima.

Best Publications

  • Enhancement of gene expression by polyamidoamine dendrimer conjugates with alpha-, beta-, and gamma-cyclodextrins.

    Hidetoshi Arima;Fumihiro Kihara;Fumitoshi Hirayama;Kaneto Uekama

  • Rutin-enhanced antibacterial activities of flavonoids against Bacillus cereus and Salmonella enteritidis

    Hidetoshi Arima;Hitoshi Ashida;Gen-ichi Danno

  • Cyclodextrins in transdermal and rectal delivery.

    Hajime Matsuda;Hidetoshi Arima

  • In vitro and in vivo gene transfer by an optimized α-cyclodextrin conjugate with polyamidoamine dendrimer

    Fumihiro Kihara;Hidetoshi Arima;Toshihito Tsutsumi;Fumitoshi Hirayama

  • Pharmaceutical evaluation of hydroxyalkyl ethers of β-cyclodextrins

    Atsuya Yoshida;Hidetoshi Arima;Kaneto Uekama;Josef Pitha

  • Colon-specific delivery of prednisolone-appended α-cyclodextrin conjugate : Alleviation of systemic side effect after oral administration

    Hideki Yano;Fumitoshi Hirayama;Makoto Kamada;Hidetoshi Arima

  • Effects of structure of polyamidoamine dendrimer on gene transfer efficiency of the dendrimer conjugate with α-cyclodextrin

    Fumihiro Kihara;Hidetoshi Arima;Toshihito Tsutsumi;Fumitoshi Hirayama

  • Improvement of gene delivery mediated by mannosylated dendrimer/α-cyclodextrin conjugates

    Koki Wada;Hidetoshi Arima;Toshihito Tsutsumi;Yuko Chihara

  • Comparative studies of the enhancing effects of cyclodextrins on the solubility and oral bioavailability of tacrolimus in rats.

    Hidetoshi Arima;Kiyokazu Yunomae;Kouzou Miyake;Tetsumi Irie

  • Methyl-beta-cyclodextrin improves fertilizing ability of C57BL/6 mouse sperm after freezing and thawing by facilitating cholesterol efflux from the cells

    Toru Takeo;Takayuki Hoshii;Yuki Kondo;Hiroshi Toyodome

  • Evaluation of polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) as a novel carrier for small interfering RNA (siRNA)

    Toshihito Tsutsumi;Fumitoshi Hirayama;Kaneto Uekama;Hidetoshi Arima

  • Improvement of Solubility and Oral Bioavailability of Rutin by Complexation with 2-Hydroxypropyl-β-cyclodextrin

    Kouzou Miyake;Hidetoshi Arima;Fumitoshi Hirayama;Masanobu Yamamoto

  • Contribution of P-glycoprotein to the enhancing effects of dimethyl-beta-cyclodextrin on oral bioavailability of tacrolimus.

    Hidetoshi Arima;Kiyokazu Yunomae;Fumitoshi Hirayama;Kaneto Uekama

  • Enhancing effects of cyclodextrins on nasal absorption of insulin in rats

    Tetsumi Irie;Koutarou Wakamatsu;Hidetoshi Arima;Hideaki Aritomi

  • Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier.

    Hidetoshi Arima;Ayumi Yoshimatsu;Haruna Ikeda;Ayumu Ohyama

  • Enhancement of oral bioavailability of coenzyme Q10 by complexation with γ-cyclodextrin in healthy adults

    Keiji Terao;Daisuke Nakata;Hiroshi Fukumi;Gerhard Schmid

  • In Vitro and In Vivo gene delivery mediated by Lactosylated Dendrimer/α-Cyclodextrin Conjugates (G2) into Hepatocytes

    Hidetoshi Arima;Shogo Yamashita;Yoshimasa Mori;Yuya Hayashi

  • Involvement of cholesterol in the inhibitory effect of dimethyl-β-cyclodextrin on P-glycoprotein and MRP2 function in Caco-2 cells

    Kiyokazu Yunomae;Hidetoshi Arima;Fumitoshi Hirayama;Kaneto Uekama

  • Recent Aspect of Cyclodextrin-Based Drug Delivery System

    Kaneto Uekama;Fumitoshi Hirayama;Hidetoshi Arima

  • Characterization of itraconazole/2-hydroxypropyl-β-cyclodextrin inclusion complex in aqueous propylene glycol solution

    K. Miyake;T. Irie;H. Arima;F. Hirayama

Frequent Co-Authors

Kaneto Uekama
Kaneto Uekama Sojo University
Fumitoshi Hirayama
Fumitoshi Hirayama Sojo University
Naomi Nakagata
Naomi Nakagata Kumamoto University
Seiji Okada
Seiji Okada Kumamoto University
Jun Li
Jun Li National University of Singapore
Fumio Hirata
Fumio Hirata Toyota Motor Corporation (Japan)
Toru Maruyama
Toru Maruyama Kumamoto University
Takuro Niidome
Takuro Niidome Kumamoto University
Masaki Otagiri
Masaki Otagiri Sojo University
Ken Ichi Yamamura
Ken Ichi Yamamura Kumamoto University

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