D-Index & Metrics Best Publications
Fumitoshi Hirayama

Fumitoshi Hirayama

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 58 Citations 12,954 285 World Ranking 7150 National Ranking 526

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Enzyme
  • Biochemistry

Fumitoshi Hirayama focuses on Cyclodextrin, Chromatography, Solubility, Drug carrier and Stereochemistry. His research in the fields of Inclusion compound overlaps with other disciplines such as Conjugate. His Chromatography study incorporates themes from Oral administration and Pharmacology toxicology.

His research integrates issues of Stability constants of complexes, Aqueous solution, Bioavailability and Dissolution in his study of Solubility. The concepts of his Drug carrier study are interwoven with issues in Combinatorial chemistry and Dosage form. His Combinatorial chemistry study integrates concerns from other disciplines, such as Targeted drug delivery and 2 hydroxypropyl β cyclodextrin.

His most cited work include:

  • Cyclodextrin Drug Carrier Systems. (1797 citations)
  • Cyclodextrin-based controlled drug release system. (379 citations)
  • Enhancement of gene expression by polyamidoamine dendrimer conjugates with α-, β-, and γ-cyclodextrins (195 citations)

What are the main themes of his work throughout his whole career to date?

Fumitoshi Hirayama mostly deals with Cyclodextrin, Solubility, Chromatography, Stereochemistry and Organic chemistry. His work on Inclusion compound as part of general Cyclodextrin study is frequently linked to Conjugate, bridging the gap between disciplines. His biological study deals with issues like Dissolution, which deal with fields such as Nuclear chemistry and Absorption.

As a part of the same scientific study, he usually deals with the Chromatography, concentrating on Bioavailability and frequently concerns with Oral administration, Intestinal absorption and Absorption. His Stereochemistry research includes elements of Hemolysis and Carboxylic acid. As a member of one scientific family, Fumitoshi Hirayama mostly works in the field of Dosage form, focusing on Drug carrier and, on occasion, Combinatorial chemistry.

He most often published in these fields:

  • Cyclodextrin (52.54%)
  • Solubility (23.73%)
  • Chromatography (22.71%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cyclodextrin (52.54%)
  • Oxidative stress (4.41%)
  • Chromatography (22.71%)

In recent papers he was focusing on the following fields of study:

Fumitoshi Hirayama spends much of his time researching Cyclodextrin, Oxidative stress, Chromatography, Antioxidant and Nuclear chemistry. His research in Cyclodextrin intersects with topics in Ether, Self-healing hydrogels, Polymer chemistry, Insulin and Solubility. Fumitoshi Hirayama has included themes like Cationic polymerization, Stability constants of complexes, Drug carrier and Glimepiride in his Solubility study.

His Oxidative stress research is multidisciplinary, incorporating perspectives in Chronic renal failure, Gastrointestinal tract and Pharmacology. His work carried out in the field of Chromatography brings together such families of science as Rheology, Dynamic mechanical analysis, Micelle, Aqueous solution and Polysaccharide. Fumitoshi Hirayama has researched Nuclear chemistry in several fields, including Benzyl acetate, Radical, Beta-Cyclodextrins and Dissolution.

Between 2012 and 2021, his most popular works were:

  • Antioxidant activities of chitosans and its derivatives in in vitro and in vivo studies. (49 citations)
  • Effects of chitosan on oxidative stress and related factors in hemodialysis patients (23 citations)
  • Hydrophobically Modified Polymer/α-Cyclodextrin Thermoresponsive Hydrogels for Use in Ocular Drug Delivery (22 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • Biochemistry

Fumitoshi Hirayama focuses on Antioxidant, Chromatography, Cyclodextrin, Oxidative stress and Chitosan. His studies in Chromatography integrate themes in fields like Denaturation and Circular dichroism. His Cyclodextrin study combines topics in areas such as Crystallization, Amorphous solid, Crystallography, Polymer chemistry and Freeze-drying.

His study on Oxidative stress also encompasses disciplines like

  • Peroxynitrite, which have a strong connection to Pharmacology, Alanine transaminase, Reactive nitrogen species and Trolox,
  • Ingestion and related Renal injury, Creatinine and Gastrointestinal tract. The concepts of his Chitosan study are interwoven with issues in In vivo, In vivo absorption, Sulfobutyl ether β cyclodextrin, Controlled release and Dissolution. His In vivo research incorporates elements of Absorption, In vitro and Hyperphosphatemia.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cyclodextrin Drug Carrier Systems.

Kaneto Uekama;Fumitoshi Hirayama;Tetsumi Irie.
Chemical Reviews (1998)

3062 Citations

Cyclodextrin-based controlled drug release system.

F Hirayama;K Uekama.
Advanced Drug Delivery Reviews (1999)

629 Citations

Enhancement of gene expression by polyamidoamine dendrimer conjugates with alpha-, beta-, and gamma-cyclodextrins.

Hidetoshi Arima;Fumihiro Kihara;Fumitoshi Hirayama;Kaneto Uekama.
Bioconjugate Chemistry (2001)

306 Citations

Inclusi on complexations of steroid hormones with cyclodextrins in water and in solid phase

K Uekama;T Fujinaga;F Hirayama;M Otagiri.
International Journal of Pharmaceutics (1982)

289 Citations

In vitro and in vivo gene transfer by an optimized α-cyclodextrin conjugate with polyamidoamine dendrimer

Fumihiro Kihara;Hidetoshi Arima;Toshihito Tsutsumi;Fumitoshi Hirayama.
Bioconjugate Chemistry (2003)

223 Citations

Improvement of gene delivery mediated by mannosylated dendrimer/α-cyclodextrin conjugates

Koki Wada;Hidetoshi Arima;Toshihito Tsutsumi;Yuko Chihara.
Journal of Controlled Release (2005)

195 Citations

Effects of structure of polyamidoamine dendrimer on gene transfer efficiency of the dendrimer conjugate with α-cyclodextrin

Fumihiro Kihara;Hidetoshi Arima;Toshihito Tsutsumi;Fumitoshi Hirayama.
Bioconjugate Chemistry (2002)

195 Citations

Evaluation of polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) as a novel carrier for small interfering RNA (siRNA)

Toshihito Tsutsumi;Fumitoshi Hirayama;Kaneto Uekama;Hidetoshi Arima.
Journal of Controlled Release (2007)

178 Citations

Comparative studies of the enhancing effects of cyclodextrins on the solubility and oral bioavailability of tacrolimus in rats.

Hidetoshi Arima;Kiyokazu Yunomae;Kouzou Miyake;Tetsumi Irie.
Journal of Pharmaceutical Sciences (2001)

176 Citations

Determination of the Stability Constants for Inclusion Complexes of Cyclodextrins with Various Drug Molecules by High Performance Liquid Chromatography

Kaneto Uekama;Fumitoshi Hirayama;Shouzo Nasu;Naoki Matsuo.
Chemical & Pharmaceutical Bulletin (1978)

154 Citations

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