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Biology and Biochemistry

D-Index
75
Citations
24105
World Ranking
5247
National Ranking
2497

Overview

David F. Stern is affiliated with Yale University in the United States. Their research spans multiple fields, focusing particularly on biochemistry, genetics, molecular biology, and computer science. Their work reflects an intersection of biological sciences and computational methods, addressing complex problems in cancer biology and related biomedical areas.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Computer Science

More specifically, their research engages subfields such as molecular biology, cancer research, pulmonary and respiratory medicine, modeling and simulation, and computational theory and mathematics. This multidisciplinary approach supports investigations into tumor biology, cancer genomics, and mathematical models of disease progression.

The primary topics covered in their work focus on:

  • Cancer Genomics and Diagnostics
  • Single-cell and Spatial Transcriptomics
  • Mathematical Biology Tumor Growth
  • Lung Cancer Treatments and Mutations
  • Ferroptosis and Cancer Prognosis
  • Computational Drug Discovery Methods
  • Vaccines and Immunoinformatics Approaches

Regarding recent publications, several papers illustrate their research contributions in these areas. These include:

  • Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations, 2021, published in npj Breast Cancer
  • Identifying modules of cooperating cancer drivers, 2021, published in Molecular Systems Biology
  • Identifying Modules of Cooperating Cancer Drivers, 2020, published in bioRxiv (Cold Spring Harbor Laboratory)
  • A digital pathology tool for quantification of color features in histologic specimens, 2021, published in Bioengineering & Translational Medicine

Frequent coauthors collaborating with David F. Stern include Michael Klein, Vincent L. Cannataro, Jeffrey P. Townsend, Scott Newman, and Hongyu Zhao. Their collaboration often covers studies on cancer biology, computational modeling, and pathology.

Publication venues where their work has appeared reflect a focus on both specialized cancer research journals and broader biomedical engineering and systems biology outlets. These venues include npj Breast Cancer, Molecular Systems Biology, bioRxiv (Cold Spring Harbor Laboratory), and Bioengineering & Translational Medicine.

Best Publications

  • The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen.

    Alan L. Schechter;David F. Stern;Lalitha Vaidyanathan;Stuart J. Decker

  • The biology of erbB-2/neu/HER-2 and its role in cancer.

    Nancy E. Hynes;David F. Stern

  • Type beta transforming growth factor: a bifunctional regulator of cellular growth.

    Anita B. Roberts;Mario A. Anzano;Lalage M. Wakefield;Nanette S. Roche

  • Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

    Michael Krauthammer;Yong Lin Kong;Byung Hak Ha;Perry Evans

  • Global Analysis of Protein Phosphorylation in Yeast

    Jason Ptacek;Geeta Devgan;Gregory Michaud;Heng Zhu

  • Specificity within the EGF family/ErbB receptor family signaling network.

    David J. Riese;David F. Stern

  • Endothelial Nitric Oxide Synthase Is Regulated by Tyrosine Phosphorylation and Interacts with Caveolin-1

    Guillermo García-Cardeña;Roger Fan;David F. Stern;Jianwei Liu

  • Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies.

    Jeffrey A. Drebin;Victoria C. Link;Victoria C. Link;David F. Stern;Robert A. Weinberg

  • Rad53 FHA Domain Associated with Phosphorylated Rad9 in the DNA Damage Checkpoint

    Zhaoxia Sun;James Hsiao;David S. Fay;David F. Stern

  • The cellular response to neuregulins is governed by complex interactions of the erbB receptor family.

    D J Riese;T M van Raaij;G D Plowman;G C Andrews

  • The Ick tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

    Andrey S. Shaw;Kurt E. Amrein;Craig Hammond;David F. Stern

  • Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs

    Janine Mok;Philip M. Kim;Philip M. Kim;Hugo Y.K. Lam;Stacy Piccirillo

  • Ligands for ErbB-family receptors encoded by a neuregulin-like gene

    Han Chang;David J. Riese;Walter Gilbert;David F. Stern

  • Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways.

    Zhaoxia Sun;David S. Fay;Federica Marini;Marco Foiani

  • Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality.

    Hester Tidcombe;Amy Jackson-Fisher;Kathleen Mathers;David F. Stern

  • Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-beta.

    Riese Dj nd;Bermingham Y;van Raaij Tm;Buckley S

  • Rad9 Phosphorylation Sites Couple Rad53 to the Saccharomyces cerevisiae DNA Damage Checkpoint

    Marc F Schwartz;Jimmy K Duong;Zhaoxia Sun;Jon S Morrow

  • EGF-stimulated tyrosine phosphorylation of p185neu: a potential model for receptor interactions.

    D F Stern;M P Kamps

  • Relationship of Epidermal Growth Factor Receptor Expression to ErbB-2 Signaling Activity and Prognosis in Breast Cancer Patients

    Michael P. DiGiovanna;David F. Stern;Susan M. Edgerton;Steve G. Whalen

  • Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases.

    David F Stern

Frequent Co-Authors

Marcus Bosenberg
Marcus Bosenberg Yale University
Xingzhi Xu
Xingzhi Xu Shenzhen University
Hongyu Zhao
Hongyu Zhao Yale University
Jeffrey P. Townsend
Jeffrey P. Townsend Yale University
David L. Rimm
David L. Rimm Yale University
Ann D. Thor
Ann D. Thor University of Colorado Anschutz Medical Campus
Ruth Halaban
Ruth Halaban Yale University
Michael Snyder
Michael Snyder Stanford University
Brenda J. Andrews
Brenda J. Andrews University of Toronto
Klaus Elenius
Klaus Elenius University of Turku

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