World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
99
Citations
35460
World Ranking
1591
National Ranking
891

Overview

John E. Shively is affiliated with the City Of Hope National Medical Center in the United States. Their research primarily focuses on medicine, with a significant emphasis on oncology, radiology, nuclear medicine and imaging, immunology, molecular biology, and hematology.

The scientist has contributed extensively to several main topics of study, including:

  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Radiopharmaceutical Chemistry and Applications
  • Cancer Immunotherapy and Biomarkers
  • Peptidase Inhibition and Analysis
  • Immunotherapy and Immune Responses
  • Multiple Myeloma Research and Treatments

John E. Shively's frequent co-authors reflect collaborations with key researchers such as Paul J. Yazaki, Erasmus Poku, Maciej Kujawski, Jeffrey Y.C. Wong, and Vikram Adhikarla.

The scientist has published articles across several notable venues, including:

  • Journal of Nuclear Medicine
  • Pharmaceuticals
  • Blood Advances
  • Cancer Biotherapy and Radiopharmaceuticals
  • European Journal of Clinical Investigation

Among the recent papers, noteworthy works include:

  • "Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting" (2020) published in Leukemia
  • "The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils" (2020) published in mBio
  • "Tumor regression and immunity in combination therapy with anti-CEA chimeric antigen receptor T cells and anti-CEA-IL2 immunocytokine" (2021) published in OncoImmunology
  • "Identifying CD38+ cells in patients with multiple myeloma: first-in-human imaging using copper-64-labeled daratumumab" (2020) published in Blood Advances
  • "Comparison of CD38-Targeted α- Versus β-Radionuclide Therapy of Disseminated Multiple Myeloma in an Animal Model" (2020) published in Journal of Nuclear Medicine

Best Publications

  • A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes.

    Nancy A. Thornberry;Herbert G. Bull;Jimmy R. Calaycay;Kevin T. Chapman

  • Formation of anhydrosugars in the chemical depolymerization of heparin.

    John E. Shively;H. Edward Conrad

  • Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-CH3) Which Exhibits Rapid, High-Level Targeting of Xenografts

    Shi-zhen Hu;Louise Shively;Andrew Raubitschek;Mark Sherman

  • Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues.

    Bon-Chu Chung;James Picado-Leonard;Mitsuru Haniu;Michael Bienkowski

  • Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes.

    David Pearson;John E. Shively;Brian R. Clark;Irving I. Geschwind

  • Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid.

    D E Ryan;L Ramanathan;S Iida;P E Thomas

  • Microsomal cytochrome P-450 from neonatal pig testis: two enzymatic activities (17 alpha-hydroxylase and c17,20-lyase) associated with one protein.

    Shizuo Nakajin;John Shively;Pau-Miau Yuan;Peter F. Hall

  • Hormone-sensitive lipase: sequence, expression, and chromosomal localization to 19 cent-q13.3.

    Cecilia Holm;Todd G. Kirchgessner;Karen L. Svenson;Gudrun Fredrikson

  • CEA-related antigens: molecular biology and clinical significance.

    John E. Shively;J. David Beatty

  • Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli

    S Cabilly;A D Riggs;H Pande;J E Shively

  • A novel active pentapeptide from chicken brain identified by antibodies to FMRFamide.

    G. J. Dockray;J. R. Reeve;J. Shively;R. J. Gayton

  • Identification of des-(Gly-Ile)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor

    Marc J. Besman;Kazutoshi Yanagibashi;Terry D. Lee;Masahiro Kawamura

  • 124I-Labeled Engineered Anti-CEA Minibodies and Diabodies Allow High-Contrast, Antigen-Specific Small-Animal PET Imaging of Xenografts in Athymic Mice

    Gobalakrishnan Sundaresan;Paul J. Yazaki;John E. Shively;Ronald D. Finn

  • Human aromatase: cDNA cloning, Southern blot analysis, and assignment of the gene to chromosome 15.

    Shiuan Chen;Marc J. Besman;Robert S. Sparkes;Susan Zollman

  • Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene family.

    Raymond J. Paxton;Gregory Mooser;Hema Pande;Terry D. Lee

  • C21 steroid side chain cleavage enzyme from porcine adrenal microsomes. Purification and characterization of the 17 alpha-hydroxylase/C17,20-lyase cytochrome P-450.

    S Nakajin;M Shinoda;M Haniu;J E Shively

  • Tumor localization of anti-CEA single-chain Fvs: improved targeting by non-covalent dimers

    Anna M. Wu;Wengang Chen;Andrew Raubitschek;Lawrence E. Williams

  • Hormonal regulation, tissue distribution, and content of aromatase cytochrome P450 messenger ribonucleic acid and enzyme in rat ovarian follicles and corpora lutea: relationship to estradiol biosynthesis.

    Gerard J. Hickey;Shiuan Chen;Marc J. Besman;John E. Shively

  • Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase

    T Iyanagi;M Haniu;K Sogawa;Y Fujii-Kuriyama

  • High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment

    Anna M. Wu;Paul J. Yazaki;Shih-wa Tsai;Khoi Nguyen

Frequent Co-Authors

Anna M. Wu
Anna M. Wu City Of Hope National Medical Center
David H. Hawke
David H. Hawke The University of Texas MD Anderson Cancer Center
Shiuan Chen
Shiuan Chen City Of Hope National Medical Center
Wayne Levin
Wayne Levin Roche (Switzerland)
Stephen J. Forman
Stephen J. Forman City Of Hope National Medical Center
Stanley Stein
Stanley Stein Rutgers, The State University of New Jersey
Dene E. Ryan
Dene E. Ryan Roche (Switzerland)
Paul E. Thomas
Paul E. Thomas Rutgers, The State University of New Jersey
Arthur D. Riggs
Arthur D. Riggs City Of Hope National Medical Center
Sidney Udenfriend
Sidney Udenfriend Roche Institute of Molecular Biology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing John E. Shively

Trending Scientists

Recently Published Articles