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Biology and Biochemistry

D-Index
78
Citations
29391
World Ranking
4464
National Ranking
2169

Overview

Anna M. Wu is affiliated with the City Of Hope National Medical Center in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with extensive work in the subfields of Oncology, Radiology, Nuclear Medicine and Imaging, Immunology, Molecular Biology, and Biomedical Engineering.

Their research interests encompass several main topics, including Radiopharmaceutical Chemistry and Applications, CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, Monoclonal and Polyclonal Antibodies Research, Advanced biosensing and bioanalysis techniques, and Nanoplatforms for cancer theranostics.

Anna M. Wu has contributed to a variety of research papers. Some notable recent publications include:

  • CD8-targeted PET Imaging of Tumor Infiltrating T cells in Patients with Cancer: A Phase I First-in-Human Study of 89Zr-Df-IAB22M2C, a Radiolabeled anti-CD8 Minibody (2021, Journal of Nuclear Medicine)
  • Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist (2020, Nature Communications)
  • Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity (2021, Molecular Therapy)
  • In vivo NIR-II structured-illumination light-sheet microscopy (2021, Proceedings of the National Academy of Sciences)
  • Shortwave-infrared-light-emitting probes for the in vivo tracking of cancer vaccines and the elicited immune responses (2023, Nature Biomedical Engineering)

The scientist has collaborated frequently with several co-authors, including Felix B. Salazar, Paul J. Yazaki, John E. Shively, Kirstin A. Zettlitz, and Erasmus Poku.

Anna M. Wu's publications have appeared extensively in specific venues, with multiple works published in Cancer Research, Regular and Young Investigator Award Abstracts, Blood Advances, Molecular Imaging and Biology, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics

    X. Michalet;F. F. Pinaud;L. A. Bentolila;J. M. Tsay

  • Arming antibodies: prospects and challenges for immunoconjugates

    Anna M Wu;Peter D Senter

  • Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-CH3) Which Exhibits Rapid, High-Level Targeting of Xenografts

    Shi-zhen Hu;Louise Shively;Andrew Raubitschek;Mark Sherman

  • Expression of recombinant antibodies in mammalian cell lines.

    Paul J. Yazaki;Anna M. Wu

  • Particle Size, Surface Coating, and PEGylation Influence the Biodistribution of Quantum Dots in Living Mice

    Meike L. Schipper;Gopal Iyer;Ai Leen Koh;Zhen Cheng

  • Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output.

    Andreas Markus Loening;Timothy David Fenn;Anna M. Wu;Sanjiv Sam Gambhir;Sanjiv Sam Gambhir

  • Effect of fixation on the amplification of nucleic acids from paraffin-embedded material by the polymerase chain reaction.

    Jonathan Ben-Ezra;David A. Johnson;John Rossi;Nathan Cook

  • The complete nucleotide sequence of the tryptophan operon of Escherichia coli

    C. Yanofsky;T. Platt;I.P. Crawford;B.P. Nichols

  • Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

    Jianqin Lu;Xiangsheng Liu;Yu-Pei Liao;Felix Salazar

  • Red-shifted Renilla reniformis luciferase variants for imaging in living subjects

    Andreas Markus Loening;Anna M Wu;Sanjiv Sam Gambhir;Sanjiv Sam Gambhir

  • 124I-Labeled Engineered Anti-CEA Minibodies and Diabodies Allow High-Contrast, Antigen-Specific Small-Animal PET Imaging of Xenografts in Athymic Mice

    Gobalakrishnan Sundaresan;Paul J. Yazaki;John E. Shively;Ronald D. Finn

  • Antibody Vectors for Imaging

    Tove Olafsen;Anna M. Wu

  • An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.

    Richard Tavaré;Helena Escuin-Ordinas;Stephen Mok;Melissa N. McCracken

  • Tumor localization of anti-CEA single-chain Fvs: improved targeting by non-covalent dimers

    Anna M. Wu;Wengang Chen;Andrew Raubitschek;Lawrence E. Williams

  • High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment

    Anna M. Wu;Paul J. Yazaki;Shih-wa Tsai;Khoi Nguyen

  • Optical Bioluminescence and Positron Emission Tomography Imaging of a Novel Fusion Reporter Gene in Tumor Xenografts of Living Mice

    Pritha Ray;Anna M. Wu;Sanjiv S. Gambhir

  • Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.

    Vania Kenanova;Tove Olafsen;Desiree M. Crow;Gobalakrishnan Sundaresan

  • Reversal of the malignant phenotype by an anti-ras ribozyme.

    M. Kashani-Sabet;T. Funato;T. Tone;L. Jiao

  • microPET-Based Biodistribution of Quantum Dots in Living Mice

    Meike L. Schipper;Zhen Cheng;Sheen-Woo Lee;Laurent A. Bentolila

  • Cd20-specific redirected t cells and their use in cellular immunotherapy of cd20+ malignancies

    Andrew Raubitschek;Michael C Jensen;Anna M Wu

Frequent Co-Authors

John E. Shively
John E. Shively City Of Hope National Medical Center
Robert E. Reiter
Robert E. Reiter University of California, Los Angeles
Sanjiv S. Gambhir
Sanjiv S. Gambhir Stanford University
Stephen J. Forman
Stephen J. Forman City Of Hope National Medical Center
James D. Marks
James D. Marks University of California, San Francisco
Jason S. Lewis
Jason S. Lewis Memorial Sloan Kettering Cancer Center
Sung-Cheng Huang
Sung-Cheng Huang University of California, Los Angeles
Shimon Weiss
Shimon Weiss University of California, Los Angeles
Jonathan Braun
Jonathan Braun Cedars-Sinai Medical Center
Michael J. Morris
Michael J. Morris Memorial Sloan Kettering Cancer Center

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