James D. Marks

Overview

Best Publications

• Methods for producing members of specific binding pairs

  John Mccafferty;Anthony Richard Pope;Kevin Stuart Johnson;Hendricus Renerus Jacobus Mattheus Hoogenboom

  2740
  Citations

• By-passing immunization: Human antibodies from V-gene libraries displayed on phage

  James D. Marks;Hennie R. Hoogenboom;Timothy P. Bonnert;John McCafferty

  2706
  Citations

• Production of anti-self antibodies from antibody segment repertoires and displayed on phage

  Andrew David Lilac Court Griffiths;Hendricus Renerus Jacobus Mattheus Hoogenboom;James David Marks;John Mccafferty

  2202
  Citations

• Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models.

  Dmitri B. Kirpotin;Daryl C. Drummond;Yi Shao;M. Refaat Shalaby

  1463
  Citations

• Human anti‐self antibodies with high specificity from phage display libraries.

  A D Griffiths;M Malmqvist;J D Marks;J M Bye

  1419
  Citations

• Multivalent and multispecific binding proteins, their manufacture and use

  Kaspar-Philipp Holliger;Andrew David Griffiths;Hendricus Renerus Jacobus Matheus Hoogenboom;Magnus Malmqvist

  1251
  Citations

• By-passing immunization: building high affinity human antibodies by chain shuffling.

  James D. Marks;Andrew D. Griffiths;Magnus Malmqvist;Tim P. Clackson

  1143
  Citations

• Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery.

  John W Park;Keelung Hong;Dmitri B Kirpotin;Gail Colbern

  1002
  Citations

• The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops.

  Ian M. Tomlinson;Gerald Walter;James D. Marks;Meirion B. Llewelyn

  964
  Citations

• High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules.

  Gregory P. Adams;Robert Schier;Adrian M. McCall;Heidi H. Simmons

  897
  Citations

• Efficient construction of a large nonimmune phage antibody library: The production of high-affinity human single-chain antibodies to protein antigens

  Michael D. Sheets;Peter Amersdorfer;Ricarda Finnern;Peter Sargent

  740
  Citations

• Structural repertoire of the human VH segments.

  Cyrus Chothia;Arthur M. Lesk;Ermanno Gherardi;Ian M. Tomlinson

  720
  Citations

• Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock.

  J M Luce;A B Montgomery;J D Marks;J Turner

  708
  Citations

• Isolation of Picomolar Affinity Anti-c-erbB-2 Single-chain Fv by Molecular Evolution of the Complementarity Determining Regions in the Center of the Antibody Binding Site

  Robert Schier;Adrian McCall;Gregory P. Adams;Keith W. Marshall

  595
  Citations

• Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection.

  Robert Schier;Jacqueline Bye;Gerald Apell;Adrian McCall

  502
  Citations

• Potent neutralization of botulinum neurotoxin by recombinant oligoclonal antibody.

  A. Nowakowski;C. Wang;D. B. Powers;P. Amersdorfer

  496
  Citations

• Epidermal Growth Factor Receptor (EGFR)-targeted Immunoliposomes Mediate Specific and Efficient Drug Delivery to EGFR- and EGFRvIII-overexpressing Tumor Cells

  Christoph Mamot;Daryl C Drummond;Udo Greiser;Keelung Hong

  474
  Citations

• Tumor targeting using anti-her2 immunoliposomes

  J.W. Park;D.B. Kirpotin;K. Hong;R. Shalaby

  469
  Citations

• Plasma tumor necrosis factor in patients with septic shock. Mortality rate, incidence of adult respiratory distress syndrome, and effects of methylprednisolone administration

  James D. Marks;Cara Berman Marks;John M. Ljuce;A. Bruce Montgomery

  467
  Citations

• Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system.

  J D Marks;H R Hoogenboom;A D Griffiths;G Winter

  433
  Citations