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Federico Da Settimo

Federico Da Settimo

University of Pisa
Italy

D-Index & Metrics

Chemistry

D-Index
42
Citations
5797
World Ranking
17592
National Ranking
709

Federico Da Settimo publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Federico Da Settimo sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 184 publications — 27th percentile

27% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Federico Da Settimo D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Federico Da Settimo sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 42 D-Index — 3rd percentile

3% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Federico Da Settimo is affiliated with the University of Pisa in Italy. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, their work spans several subfields, including Molecular Biology, Organic Chemistry, Oncology, Cellular and Molecular Neuroscience, and Physiology.

Their scientific contributions cover multiple research topics, such as:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Enzyme function and inhibition
  • Cholinesterase and Neurodegenerative Diseases
  • Adenosine and Purinergic Signaling
  • Synthesis and biological activity
  • Click Chemistry and Applications
  • Cancer therapeutics and mechanisms

Federico Da Settimo has frequently published in journals including:

  • Molecules (6 publications)
  • European Journal of Medicinal Chemistry (4 publications)
  • Journal of Medicinal Chemistry (3 publications)
  • Journal of Enzyme Inhibition and Medicinal Chemistry (3 publications)
  • European Journal of Pharmaceutical Sciences (2 publications)

Major recent papers authored or coauthored by Federico Da Settimo include:

  • "The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities", 2021, Journal of Medicinal Chemistry
  • "An update into the medicinal chemistry of translocator protein (TSPO) ligands", 2020, European Journal of Medicinal Chemistry
  • "Multiple Topoisomerase I (TopoI), Topoisomerase II (TopoII) and Tyrosyl-DNA Phosphodiesterase (TDP) inhibitors in the development of anticancer drugs", 2020, European Journal of Pharmaceutical Sciences
  • "Two mixed valence diruthenium(ii,iii) isomeric complexes show different anticancer properties", 2021, Dalton Transactions
  • "Carbonic Anhydrase Activators for Neurodegeneration: An Overview", 2022, Molecules

Collaboration is an important element of their work, with frequent co-authors including Sabrina Taliani, Elisabetta Barresi, Emma Baglini, Silvia Salerno, and Claudia Martini.

Best Publications

  • Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

    Alma Martelli;Lara Testai;Valentina Citi;Alice Marino

  • 11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.

    Masamichi Ikawa;Talakad G. Lohith;Stal Shrestha;Sanjay Telu

  • Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity.

    Concettina La Motta;Stefania Sartini;Laura Mugnaini;Francesca Simorini

  • Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications

    Rosaria Ottanà;Rosanna Maccari;Marco Giglio;Antonella Del Corso

  • Inhibition of Adenosine Deaminase Attenuates Inflammation in Experimental Colitis

    Luca Antonioli;Matteo Fornai;Rocchina Colucci;Narcisa Ghisu

  • Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971.

    Paolo Zanotti-Fregonara;Yi Zhang;Kimberly J. Jenko;Robert L. Gladding

  • Sampling protein motion and solvent effect during ligand binding

    Vittorio Limongelli;Luciana Marinelli;Sandro Cosconati;Concettina La Motta

  • Synthesis, in vitro antiproliferative activity and DNA-interaction of benzimidazoquinazoline derivatives as potential anti-tumor agents.

    Lisa Dalla Via;Ornella Gia;Sebastiano Marciani Magno;Antonio Da Settimo

  • The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities

    Marco Robello;Elisabetta Barresi;Emma Baglini;Silvia Salerno

  • Novel Pyrazolopyrimidine Derivatives as Tyrosine Kinase Inhibitors with Antitumoral Activity in Vitro and in Vivo in Papillary Dedifferentiated Thyroid Cancer

    Alessandro Antonelli;Guido Bocci;Concettina La Motta;Silvia Martina Ferrari

  • Anxiolytic-like Effects of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides by Modulation of Translocator Protein Promoting Neurosteroid Biosynthesis

    Federico Da Settimo;Francesca Simorini;Sabrina Taliani;Concettina La Motta

  • N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor

    Giampaolo Primofiore;Federico Da Settimo;Sabrina Taliani;Francesca Simorini

  • Indole amide derivatives : synthesis, structure-activity relationships and molecular modelling studies of a new series of histamine H1-receptor antagonists

    Sandra Battaglia;Enrico Boldrini;Federico Da Settimo;Giulio Dondio

  • Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2).

    Enrico Perspicace;Valérie Jouan-Hureaux;Rino Ragno;Flavio Ballante

  • TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy.

    Barbara Costa;Eleonora Da Pozzo;Chiara Giacomelli;Elisabetta Barresi

  • 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists.

    Federico Da Settimo;Giampaolo Primofiore;Sabrina Taliani;Anna Maria Marini

  • Microglial pro-inflammatory and anti-inflammatory phenotypes are modulated by translocator protein activation

    Eleonora Da Pozzo;Chiara Tremolanti;Barbara Costa;Chiara Giacomelli

  • Synthesis, DNA binding and in vitro antiproliferative activity of purinoquinazoline, pyridopyrimidopurine and pyridopyrimidobenzimidazole derivatives as potential antitumor agents

    Antonio Da Settimo;Federico Da Settimo;Anna Maria Marini;Giampaolo Primofiore

  • Genetic analysis of dTSPO, an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Aβ42‐induced neurodegeneration

    Ran Lin;Ran Lin;Alessia Angelin;Federico Da Settimo;Claudia Martini

  • Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma

    Simona Daniele;Sabrina Taliani;Eleonora Da Pozzo;Chiara Giacomelli

  • Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists

    Barbara Cosimelli;Giovanni Greco;Marina Ehlardo;Ettore Novellino

Frequent Co-Authors

Ettore Novellino
Ettore Novellino University of Naples Federico II
Claudia Martini
Claudia Martini University of Pisa
Antonio Lavecchia
Antonio Lavecchia University of Naples Federico II
Alessandro Antonelli
Alessandro Antonelli University of Pisa
Paolo Miccoli
Paolo Miccoli University of Pisa
Claudiu T. Supuran
Claudiu T. Supuran University of Florence
Romano Danesi
Romano Danesi University of Pisa
Victor W. Pike
Victor W. Pike National Institutes of Health
Robert B. Innis
Robert B. Innis National Institutes of Health
Sami S. Zoghbi
Sami S. Zoghbi National Institutes of Health

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Best Scientists Citing Federico Da Settimo

Claudia Martini

Claudia Martini

University of Pisa

Publications: 64

Ettore Novellino

Ettore Novellino

University of Naples Federico II

Publications: 40

Alessandro Antonelli

Alessandro Antonelli

University of Pisa

Publications: 36

Claudiu T. Supuran

Claudiu T. Supuran

University of Florence

Publications: 29

Carla Ghelardini

Carla Ghelardini

University of Florence

Publications: 18

Michael Kassiou

Michael Kassiou

University of Sydney

Publications: 16

György Haskó

György Haskó

Columbia University

Publications: 15

Paolo Miccoli

Paolo Miccoli

University of Pisa

Publications: 15

Vassilios Papadopoulos

Vassilios Papadopoulos

University of Southern California

Publications: 15

Michele Parrinello

Michele Parrinello

ETH Zurich

Publications: 14

Richard B. Banati

Richard B. Banati

University of Sydney

Publications: 13

Christa E. Müller

Christa E. Müller

University of Bonn

Publications: 13

Silvia Schenone

Silvia Schenone

University of Genoa

Publications: 12

Pier Andrea Borea

Pier Andrea Borea

University of Ferrara

Publications: 12

Katia Varani

Katia Varani

University of Ferrara

Publications: 12

Stefano Moro

Stefano Moro

University of Padua

Publications: 11

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