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Neuroscience

D-Index
73
Citations
19984
World Ranking
2195
National Ranking
1041

Overview

Sami S. Zoghbi is affiliated with the National Institutes of Health in the United States. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Radiology, Nuclear Medicine and Imaging, Pharmacology, Cellular and Molecular Neuroscience, and Oncology.

The main topics covered in their research include:

  • Inflammatory mediators and NSAID effects
  • Neuroscience and Neuropharmacology Research
  • Phosphodiesterase function and regulation
  • Estrogen and related hormone effects
  • Radiopharmaceutical Chemistry and Applications
  • Medical Imaging Techniques and Applications
  • Eicosanoids and Hypertension Pharmacology

Their recent publications include several articles primarily published in the year 2020 and 2021:

  • Guidelines for the content and format of PET brain data in publications and archives: A consensus paper, 2020, Journal of Cerebral Blood Flow & Metabolism
  • PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study, 2020, Journal of Neuroinflammation
  • First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain, 2020, European Journal of Nuclear Medicine and Molecular Imaging
  • [11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain, 2021, Journal of Cerebral Blood Flow & Metabolism
  • PET ligands [ 18 F]LSN3316612 and [ 11 C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain, 2020, Science Translational Medicine

Frequent publication venues for Sami S. Zoghbi include:

  • Journal of Nuclear Medicine
  • Biological Psychiatry
  • Journal of Cerebral Blood Flow & Metabolism
  • EJNMMI Research
  • ACS Chemical Neuroscience

Collaborators frequently co-authoring with this scientist are:

  • Victor W. Pike
  • Robert B. Innis
  • Jeih-San Liow
  • Cheryl L. Morse
  • Sanjay Telu

Best Publications

  • Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects

    M Laruelle;A Abi-Dargham;C H van Dyck;R Gil

  • Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers

    Hirvonen J;Goodwin Rs;Li Ct;Terry Ge

  • Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease.

    J. P. Seibyl;K. L. Marchek;D. Quinlan;K. Sheff

  • [sup 123 I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease

    K. L. Marek;J. P. Seibyl;S. S. Zoghbi;Y. Zea-Ponce

  • Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.

    R B Innis;J P Seibyl;B E Scanley;M Laruelle

  • SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT: pharmacological characterization of brain uptake in nonhuman primates.

    Marc Laruelle;Ronald M. Baldwin;Robert T. Malison;Yolanda Zea-Ponce

  • Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder.

    J D Bremner;R B Innis;S M Southwick;L Staib

  • In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease

    William C. Kreisl;Chul Hyoung Lyoo;Meghan McGwier;Joseph Snow

  • Graphical, Kinetic, and Equilibrium Analyses of in vivo [123I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects

    Marc Laruelle;Elizabeth Wallace;John P. Seibyl;Ronald M. Baldwin

  • Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker.

    William C. Kreisl;Masahiro Fujita;Yota Fujimura;Yota Fujimura;Nobuyo Kimura

  • Age-Related Decline in Dopamine Transporters: Analysis of Striatal Subregions, Nonlinear Effects, and Hemispheric Asymmetries

    Christopher H. van Dyck;John P. Seibyl;Robert T. Malison;Marc Laruelle

  • Alterations of benzodiazepine receptors in type II alcoholic subjects measured with spect and [123I]iomazenil

    Anissa Abi-Dargham;John H. Krystal;Satish Anjilvel;Barbara Ellen Scanley

  • Prediction of Dopamine Transporter Binding Availability by Genotype: A Preliminary Report

    Leslie K. Jacobsen;Julie K. Staley;Sami S. Zoghbi;John P. Seibyl

  • A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation.

    William C Kreisl;Kimberly J Jenko;Christina S Hines;Chul Hyoung Lyoo

  • Imaging D2 receptor occupancy by endogenous dopamine in humans

    Marc Laruelle;Cyril D D’Souza;Ronald M Baldwin;Anissa Abi-Dargham

  • Microdialysis and SPECT Measurements of Amphetamine-Induced Dopamine Release in Nonhuman Primates

    Marc Laruelle;Marc Laruelle;Raj N. Iyer;Raj N. Iyer;Mohammed S. Al-Tikriti;Mohammed S. Al-Tikriti;Yolanda Zea-Ponce;Yolanda Zea-Ponce

  • Increase in Prefrontal Cortex Serotonin2A Receptors Following Estrogen Treatment in Postmenopausal Women

    Akira Kugaya;C. Neill Epperson;Sami Zoghbi;Christopher H. van Dyck

  • Sex differences in [123I]β‐CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers

    Julie K. Staley;Suchitra Krishnan-Sarin;Sami Zoghbi;Gilles Tamagnan

  • Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein.

    Chul Hyoung Lyoo;Masamichi Ikawa;Jeih San Liow;Sami S. Zoghbi

  • Imaging the Function of P-Glycoprotein With Radiotracers: Pharmacokinetics and In Vivo Applications

    P Kannan;P Kannan;C John;S S Zoghbi;C Halldin

Frequent Co-Authors

Robert B. Innis
Robert B. Innis National Institutes of Health
Jussi Hirvonen
Jussi Hirvonen Turku University Hospital
Mattia Veronese
Mattia Veronese King's College London
Vanessa Cropley
Vanessa Cropley University of Melbourne
Roger N. Gunn
Roger N. Gunn Imperial College London
William H. Theodore
William H. Theodore National Institutes of Health
Nora D. Volkow
Nora D. Volkow National Institutes of Health
Eugenii A. Rabiner
Eugenii A. Rabiner King's College London
Francis J. McMahon
Francis J. McMahon National Institutes of Health
Pedro Rosa-Neto
Pedro Rosa-Neto McGill University

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