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D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
29816
World Ranking
3116
National Ranking
237

Overview

Andreas Kispert is affiliated with Hannover Medical School in Germany and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their scholarly work spans several subfields, primarily focusing on molecular biology, urology, pulmonary and respiratory medicine, pediatrics, perinatology and child health, as well as genetics.

Kispert's research frequently addresses topics related to renal and related cancers, urological disorders and treatments, epigenetics and DNA methylation, congenital heart defects research, renal cell carcinoma treatment, pediatric urology and nephrology studies, and genetics and neurodevelopmental disorders.

Prominent venues for Kispert's publications include:

  • Development
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Molecular Genetics
  • European Journal of Human Genetics
  • Journal of Hepatology

Recent papers authored or co-authored by Kispert demonstrate a range of investigative focuses in developmental biology and disease mechanisms. Key recent publications include:

  • Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9, 2024, Science Translational Medicine
  • TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti, 2022, Nature Communications
  • Regulation of otocyst patterning by Tbx2 and Tbx3 is required for inner ear morphogenesis in the mouse, 2021, Development
  • WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis, 2021, Journal of Clinical Investigation
  • A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification, 2020, Haematologica

Kispert has collaborated extensively with several researchers, with frequent co-authors including:

  • Mark-Oliver Trowe
  • Anna-Carina Weiss
  • Timo H. Lüdtke
  • Carsten Rudat
  • Lena Deuper

The research profile of Andreas Kispert highlights a focus on molecular and cellular mechanisms in development and disease, particularly relating to renal and urological domains. Their contributions cover experimental studies, mechanistic insights, and the use of stem cell and differentiation models to address questions in development and pathology.

Best Publications

  • β‐catenin is a target for the ubiquitin–proteasome pathway

    Hermann Aberle;Andreas Bauer;Jörg Stappert;Andreas Kispert

  • Female development in mammals is regulated by Wnt-4 signalling

    Seppo Vainio;Minna Heikkilä;Andreas Kispert;Norman Chin

  • A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

    Frank L. Conlon;Karen M. Lyons;Norma Takaesu;Katrin S. Barth

  • The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

    John A. Sayer;John A. Sayer;Edgar A. Otto;John F. O'Toole;Gudrun Nurnberg

  • Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination.

    Edgar A. Otto;Bernhard Schermer;Tomoko Obara;John F. O'Toole

  • Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

    Bernward Hinkes;Roger C. Wiggins;Rasheed Gbadegesin;Christopher N. Vlangos

  • Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1.

    Jochen C. Hartner;Carolin Schmittwolf;Andreas Kispert;Albrecht M. Müller

  • Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left–right asymmetry

    Heike Olbrich;Karsten Häffner;Andreas Kispert;Alexander Völkel

  • The Brachyury gene encodes a novel DNA binding protein.

    A. Kispert;B.G. Herrmann

  • Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney

    Andreas Kispert;Seppo Vainio;Andrew P. McMahon

  • Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure.

    Ralf Birkenhäger;Edgar Otto;Maria J. Schürmann;Martin Vollmer

  • Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.

    Arindam Majumdar;Seppo Vainio;Andreas Kispert;Jill McMahon

  • Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin

    Edgar A. Otto;Bart Loeys;Hemant Khanna;Jan Hellemans

  • COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

    Saskia F. Heeringa;Gil Chernin;Moumita Chaki;Weibin Zhou

  • Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis

    Heike Olbrich;Manfred Fliegauf;Julia Hoefele;Andreas Kispert

  • The T protein encoded by Brachyury is a tissue‐specific transcription factor.

    A. Kispert;B. Koschorz;B. G. Herrmann

  • Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation

    Inés Ibañez-Tallon;Axel Pagenstecher;Manfred Fliegauf;Heike Olbrich

  • CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs

    Anne-Christine Merveille;Erica E Davis;Anita Becker-Heck;Anita Becker-Heck;Marie Legendre

  • Loss of Nephrocystin-3 Function Can Cause Embryonic Lethality, Meckel-Gruber-like Syndrome, Situs Inversus, and Renal-Hepatic-Pancreatic Dysplasia

    Carsten Bergmann;Manfred Fliegauf;Nadina Ortiz Brüchle;Valeska Frank

  • Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips

    Andreas Kispert;Seppo Vainio;Liya Shen;David H. Rowitch

Frequent Co-Authors

Vincent M. Christoffels
Vincent M. Christoffels University of Amsterdam
Bernhard G. Herrmann
Bernhard G. Herrmann Max Planck Society
Friedhelm Hildebrandt
Friedhelm Hildebrandt Boston Children's Hospital
Heymut Omran
Heymut Omran University of Münster
Antoon F.M. Moorman
Antoon F.M. Moorman University of Amsterdam
Michael Leitges
Michael Leitges University of Oslo
Andrew P. McMahon
Andrew P. McMahon University of Southern California
Edgar A. Otto
Edgar A. Otto University of Michigan–Ann Arbor
Makoto Mark Taketo
Makoto Mark Taketo Kyoto University
Heike Olbrich
Heike Olbrich University Hospital Münster

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