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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
13571
World Ranking
14278
National Ranking
1009

Overview

Heike Olbrich is affiliated with the University Hospital Münster in Germany and is active in medical and genetic research fields. Their work spans multiple disciplines, including medicine, biochemistry, genetics, and molecular biology, with a focus on pulmonary and respiratory medicine, genetics, molecular biology, pediatrics, perinatology, child health, and immunology.

The scientist's research covers several main topics, particularly cystic fibrosis research advances, neonatal respiratory health research, genetic and kidney cyst diseases, as well as tracheal and airway disorders. Additional areas of interest include genetics and neurodevelopmental disorders, fetal and pediatric neurological disorders, and protist diversity and phylogeny.

Heike Olbrich has published extensively in various venues. Frequent publication outlets include UNC Libraries, Klinische Pädiatrie, European Respiratory Journal, American Journal of Respiratory and Critical Care Medicine, and Cells.

Key recent papers authored or coauthored by Heike Olbrich include:

  • CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module, 2020, Nature Communications
  • Defects in the cytoplasmic assembly of axonemal dynein arms cause morphological abnormalities and dysmotility in sperm cells leading to male infertility, 2021, PLoS Genetics
  • Multisystem inflammation and susceptibility to viral infections in human ZNFX1 deficiency, 2021, Journal of Allergy and Clinical Immunology
  • Motility of efferent duct cilia aids passage of sperm cells through the male reproductive system, 2021, Molecular Human Reproduction
  • Primary ciliary dyskinesia, 2023, La Presse Médicale

Frequent coauthors collaborating with Heike Olbrich include Heymut Omran, Johanna Raidt, Niki T. Loges, Gerard W. Dougherty, and Petra Pennekamp.

Best Publications

  • Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left–right asymmetry

    Heike Olbrich;Karsten Häffner;Andreas Kispert;Alexander Völkel

  • BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

    Stefan Pfister;Wibke G. Janzarik;Marc Remke;Aurélie Ernst

  • Congenital Heart Disease and Other Heterotaxic Defects in a Large Cohort of Patients With Primary Ciliary Dyskinesia

    Marcus P. Kennedy;Heymut Omran;Margaret W. Leigh;Sharon Dell

  • Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis

    Heike Olbrich;Manfred Fliegauf;Julia Hoefele;Andreas Kispert

  • Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins

    Heymut Omran;Daisuke Kobayashi;Daisuke Kobayashi;Heike Olbrich;Tatsuya Tsukahara

  • Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation

    Inés Ibañez-Tallon;Axel Pagenstecher;Manfred Fliegauf;Heike Olbrich

  • CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs

    Anne-Christine Merveille;Erica E Davis;Anita Becker-Heck;Anita Becker-Heck;Marie Legendre

  • Loss of Nephrocystin-3 Function Can Cause Embryonic Lethality, Meckel-Gruber-like Syndrome, Situs Inversus, and Renal-Hepatic-Pancreatic Dysplasia

    Carsten Bergmann;Manfred Fliegauf;Nadina Ortiz Brüchle;Valeska Frank

  • DNAH5 Mutations Are a Common Cause of Primary Ciliary Dyskinesia with Outer Dynein Arm Defects

    Nada Hornef;Heike Olbrich;Judit Horvath;Maimoona B Zariwala

  • The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation

    Anita Becker-Heck;Irene E Zohn;Irene E Zohn;Noriko Okabe;Andrew Pollock

  • Mislocalization of DNAH5 and DNAH9 in Respiratory Cells from Patients with Primary Ciliary Dyskinesia

    Manfred Fliegauf;Heike Olbrich;Judit Horvath;Johannes H. Wildhaber

  • Recessive HYDIN Mutations Cause Primary Ciliary Dyskinesia Without Randomization of Left-Right Body Asymmetry

    Heike Olbrich;Miriam Schmidts;Claudius Werner;Alexandros Onoufriadis

  • DYX1C1 is required for axonemal dynein assembly and ciliary motility

    Aarti Tarkar;Niki T. Loges;Christopher E. Slagle;Richard Francis

  • Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia

    Hannah M Mitchison;Miriam Schmidts;Niki T Loges;Judy Freshour

  • DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.

    Niki Tomas Loges;Heike Olbrich;Lale Fenske;Huda Mussaffi

  • Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia

    Julia Wallmeier;Dalal A Al-Mutairi;Chun-Ting Chen;Niki Tomas Loges

  • CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms

    Jennifer R Panizzi;Anita Becker-Heck;Victoria H Castleman;Dalal A Al-Mutairi;Dalal A Al-Mutairi

  • Primary Ciliary Dyskinesia Associated With Normal Axoneme Ultrastructure Is Caused by DNAH11 Mutations

    Georg C. Schwabe;Katrin Hoffmann;Niki Tomas Loges;Daniel Birker

  • MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia

    Mieke Boon;Julia Wallmeier;Lina Ma;Niki Tomas Loges

  • Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

    Huriye Cin;Claus Meyer;Ricarda Herr;Wibke G. Janzarik

Frequent Co-Authors

Heymut Omran
Heymut Omran University of Münster
Michael R. Knowles
Michael R. Knowles University of North Carolina at Chapel Hill
Hannah M. Mitchison
Hannah M. Mitchison University College London
Richard Reinhardt
Richard Reinhardt Max Planck Society
Friedhelm Hildebrandt
Friedhelm Hildebrandt Boston Children's Hospital
Gabriele Köhler
Gabriele Köhler University of Münster
Marc Remke
Marc Remke German Cancer Research Center
Andreas Kispert
Andreas Kispert Hannover Medical School
Andreas E. Kulozik
Andreas E. Kulozik Heidelberg University
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center

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