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D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
18789
World Ranking
8118
National Ranking
59

Overview

Seppo Vainio is affiliated with the University of Oulu in Finland. Their research spans a wide range of topics primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Vainio's work notably addresses molecular biology and biomedical engineering, with additional focus areas including pulmonary and respiratory medicine, surgery, and psychiatry and mental health.

The scientist's main research themes include extracellular vesicles in disease, renal and related cancers, renal cell carcinoma treatment, microRNA in disease regulation, tissue engineering and regenerative medicine, organ donation and transplantation, and reproductive biology and fertility.

Among recent publications are:

  • Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells, 2020, Nature
  • Extracellular Vesicles as Innovative Tool for Diagnosis, Regeneration and Protection against Neurological Damage, 2020, International Journal of Molecular Sciences
  • Maternal microbiota communicates with the fetus through microbiota-derived extracellular vesicles, 2023, Microbiome
  • Erbb4 regulates the oocyte microenvironment during folliculogenesis, 2020, Human Molecular Genetics
  • Biomedical applications of multifunctional magnetoelectric nanoparticles, 2022, Materials Chemistry Frontiers

Frequent co-authors throughout their career include:

  • Anatoly Samoylenko
  • Ilya Skovorodkin
  • Artem Zhyvolozhnyi
  • Geneviève Bart
  • Nsrein Ali

Vainio has published extensively in several scientific venues. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Frontiers in Physiology
  • Scientific Reports
  • IEEE Transactions on Molecular Biological and Multi-Scale Communications

This body of work reflects a focus on interdisciplinary approaches combining molecular biology techniques with biomedical engineering and clinical applications, particularly related to extracellular vesicles and cancer biology.

Best Publications

  • Female development in mammals is regulated by Wnt-4 signalling

    Seppo Vainio;Minna Heikkilä;Andreas Kispert;Norman Chin

  • Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4.

    Kevin Stark;Seppo Vainio;Galya Vassileva;Galya Vassileva;Andrew P. McMahon

  • Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

    Seppo Vainio;Irina Karavanova;Adrian Jowett;Irma Thesleff

  • Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney

    Andreas Kispert;Seppo Vainio;Andrew P. McMahon

  • Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.

    Arindam Majumdar;Seppo Vainio;Andreas Kispert;Jill McMahon

  • Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development.

    Alan O. Perantoni;Olga Timofeeva;Florence Naillat;Charmaine Richman

  • Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips

    Andreas Kispert;Seppo Vainio;Liya Shen;David H. Rowitch

  • Associations of FGF‐3 and FGF‐10 with signaling networks regulating tooth morphogenesis

    Päivi Kettunen;Johanna Laurikkala;Petri Itäranta;Seppo Vainio

  • Kidney morphogenesis: cellular and molecular regulation.

    Satu Kuure;Reetta Vuolteenaho;Seppo Vainio

  • Induced expression of syndecan in healing wounds.

    K Elenius;S Vainio;M Laato;M Salmivirta

  • Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth

    Adrian K. Jowett;Seppo Vainio;Mark W. J. Ferguson;Paul T. Sharpe

  • Coordinating early kidney development: lessons from gene targeting.

    Seppo Vainio;Yanfeng Lin

  • Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription

    Frank J. T. Staal;Jan Meeldijk;Petra Moerer;Philippe Jay

  • Wnt-4 Deficiency Alters Mouse Adrenal Cortex Function, Reducing Aldosterone Production

    Minna Heikkilä;Hellevi Peltoketo;Juhani Leppäluoto;Mika Ilves

  • Syndecan from embryonic tooth mesenchyme binds tenascin.

    M Salmivirta;K Elenius;S Vainio;U Hofer

  • Syndecan and tenascin expression is induced by epithelial-mesenchymal interactions in embryonic tooth mesenchyme.

    S Vainio;M Jalkanen;I Thesleff

  • Changes in the distribution of tenascin during tooth development.

    I. Thesleff;E. Mackie;S. Vainio;R. Chiquet-Ehrismann

  • Associations between transforming growth factor beta 1 RNA expression and epithelial-mesenchymal interactions during tooth morphogenesis.

    A. Vaahtokari;S. Vainio;I. Thesleff

  • Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.

    Rea Pihlaja;Jari Koistinaho;Tarja Malm;Herkko Sikkilä

  • Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis.

    Odyssé Michos;Alexandre Gonçalves;Javier Lopez-Rios;Eva Tiecke

Frequent Co-Authors

Irma Thesleff
Irma Thesleff University of Helsinki
Jukka Hyönä
Jukka Hyönä University of Turku
Markku Jalkanen
Markku Jalkanen Faron Pharmaceuticals
Susan E. Quaggin
Susan E. Quaggin Northwestern University
Klaus Elenius
Klaus Elenius University of Turku
Andrew P. McMahon
Andrew P. McMahon University of Southern California
Hannu Sariola
Hannu Sariola University of Helsinki
Raija Sormunen
Raija Sormunen University of Oulu
Andreas Kispert
Andreas Kispert Hannover Medical School
Nikolai G. Khlebtsov
Nikolai G. Khlebtsov Saratov State University

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