World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
11654
World Ranking
12620
National Ranking
90

Overview

Klaus Elenius is affiliated with the University of Turku in Finland. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. The scientific outputs include a considerable focus on Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Cancer Research, and Cell Biology.

The scientist's work addresses various main topics, prominently including HER2/EGFR in Cancer Research, Lung Cancer Treatments and Mutations, Cancer Genomics and Diagnostics, Cancer-related Molecular Pathways, Protein Tyrosine Phosphatases, Microtubule and Mitosis Dynamics, and Signaling Pathways in Disease.

The venues where Klaus Elenius has published repeatedly reflect their research interests. Frequent publication channels include bioRxiv (Cold Spring Harbor Laboratory) with six publications, Cancer Research with five, Cancers and Journal of Visualized Experiments with two publications each, and Human Molecular Genetics with one publication.

Key recent papers authored or co-authored by Klaus Elenius are:

  • Therapeutic Potential of Targeting the SUMO Pathway in Cancer, 2021, Cancers
  • Erbb4 regulates the oocyte microenvironment during folliculogenesis, 2020, Human Molecular Genetics
  • Structural Basis for the Functional Changes by EGFR Exon 20 Insertion Mutations, 2021, Cancers
  • The guanine nucleotide exchange factor VAV3 participates in ERBB4-mediated cancer cell migration, 2020, Journal of Biological Chemistry
  • DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer, 2024, EMBO Molecular Medicine

Collaborations with several frequent co-authors have been significant in their research career. These co-authors include Kari J. Kurppa, Deepankar Chakroborty, Katri Vaparanta, Veera K. Ojala, and Mark S. Johnson.

Best Publications

  • Amplification of HER-2 in gastric carcinoma: association with Topoisomerase IIα gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab

    M. Tanner;M. Hollmén;T. T. Junttila;A. I. Kapanen

  • ACTIVATION OF HER4 BY HEPARIN-BINDING EGF-LIKE GROWTH FACTOR STIMULATES CHEMOTAXIS BUT NOT PROLIFERATION

    Klaus Elenius;Subroto Paul;Genève Allison;Jilin Sun

  • Signaling via ErbB2 and ErbB3 Associates with Resistance and Epidermal Growth Factor Receptor (EGFR) Amplification with Sensitivity to EGFR Inhibitor Gefitinib in Head and Neck Squamous Cell Carcinoma Cells

    Kaisa Erjala;Maria Sundvall;Teemu T. Junttila;Na Zhang

  • High frequency of BRAF V600E mutations in ameloblastoma

    Kari J Kurppa;Javier Catón;Peter R Morgan;Ari Ristimäki

  • Characterization of a novel cell line established from a patient with Herceptin-resistant breast cancer

    Minna Tanner;Anita I Kapanen;Teemu Junttila;Olayinka Raheem

  • Induced expression of syndecan in healing wounds.

    K Elenius;S Vainio;M Laato;M Salmivirta

  • A Novel Juxtamembrane Domain Isoform of HER4/ErbB4 ISOFORM-SPECIFIC TISSUE DISTRIBUTION AND DIFFERENTIAL PROCESSING IN RESPONSE TO PHORBOL ESTER

    Klaus Elenius;Gabriel Corfas;Subroto Paul;Caroline J. Choi

  • Syndecan from embryonic tooth mesenchyme binds tenascin.

    M Salmivirta;K Elenius;S Vainio;U Hofer

  • Cleavable ErbB4 isoform in estrogen receptor-regulated growth of breast cancer cells.

    Teemu T. Junttila;Maria Sundvall;Mikael Lundin;Johan Lundin

  • Characterization of a naturally occurring ErbB4 isoform that does not bind or activate phosphatidyl inositol 3-kinase.

    Klaus Elenius;Caroline J Choi;Subroto Paul;Eric Santiestevan

  • The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4.

    David J. Riese;Edward D. Kim;Klaus Elenius;Sharon Buckley;Sharon Buckley

  • ERBB Receptor Signaling Promotes Ependymoma Cell Proliferation and Represents a Potential Novel Therapeutic Target for This Disease

    Richard J. Gilbertson;Lyndsay Bentley;Roberto Hernan;Teemu T. Junttila

  • Proteolytic Cleavage and Phosphorylation of a Tumor-associated ErbB4 Isoform Promote Ligand-independent Survival and Cancer Cell Growth

    Jorma A. Määttä;Maria Sundvall;Teemu T. Junttila;Liisa Peri

  • A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis.

    Varpu Kainulainen;Maria Sundvall;Jorma A. Määttä;Eric Santiestevan

  • Function of the syndecans--a family of cell surface proteoglycans.

    Klaus Elenius;Markku Jalkanen

  • Heparin-binding EGF-like growth factor interacts with mouse blastocysts independently of ErbB1: a possible role for heparan sulfate proteoglycans and ErbB4 in blastocyst implantation.

    B.C. Paria;K. Elenius;M. Klagsbrun;S.K. Dey

  • Role of ErbB4 in breast cancer

    Maria Sundvall;Kristiina Iljin;Sami Kilpinen;Henri Sara

  • Growth Factors Induce 3T3 Cells to Express bFGF-binding Syndecan*

    K Elenius;A Määttä;M Salmivirta;M Jalkanen

  • Binding of human syndecan to extracellular matrix proteins.

    K Elenius;M Salmivirta;P Inki;M Mali

  • Syndecan from embryonic tooth mesenchyme binds tenascin

    Markku Jalkanen;Markku Salmivirta;Seppo Vainio;Klaus Elenius

Frequent Co-Authors

Markku Jalkanen
Markku Jalkanen Faron Pharmaceuticals
Michael Klagsbrun
Michael Klagsbrun Boston Children's Hospital
Heikki Joensuu
Heikki Joensuu University of Helsinki
Jorma Isola
Jorma Isola Tampere University
Seppo Vainio
Seppo Vainio University of Oulu
Reidar Grénman
Reidar Grénman Turku University Hospital
Rami I. Aqeilan
Rami I. Aqeilan Hebrew University of Jerusalem
Daniel J. Leahy
Daniel J. Leahy Johns Hopkins University School of Medicine
Minna Tanner
Minna Tanner Tampere University
Guy A. Rouleau
Guy A. Rouleau Montreal Neurological Institute and Hospital

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