World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
128
Citations
62627
World Ranking
452
National Ranking
290

Overview

Michael Klagsbrun was affiliated with Boston Children's Hospital in the United States. Their research focused on topics including adipokines, inflammation, and metabolic diseases, as well as immune cells in cancer and the interplay between cancer, stress, anesthesia, and the immune response.

The scientist's work spanned several fields of study, primarily in medicine, immunology, and microbiology. Their subfields included epidemiology, immunology, and psychiatry and mental health.

Klagsbrun published research in venues such as UNC Libraries, contributing at least one documented paper during their career.

  • Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis (2020, UNC Libraries)

Frequent coauthors associated with Klagsbrun's research work included:

  • Marek Wagner
  • Rolf Bjerkvig
  • Helge Wiig
  • Juan M. Melero-Martin
  • Ruei-Zeng Lin

The range of Klagsbrun's research topics indicate a focus on the cellular and molecular interactions within the immune system as it relates to cancer progression and metabolic inflammation. Their contributions added to the understanding of how macrophages in adipose tissue can influence tumor growth and angiogenesis, signaling complex interactions between immune responses and cancer biology.

Best Publications

  • Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

    Shay Soker;Seiji Takashima;Hua Quan Miao;Gera Neufeld

  • Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor.

    Avner Yayon;Michael Klagsbrun;Jeffrey D. Esko;Philip Leder

  • A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF.

    Shigeki Higashiyama;Judith A. Abraham;Judy Miller;John C. Fiddes

  • Regulators of angiogenesis.

    M Klagsbrun;P A D'Amore

  • Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix

    Israel Vlodavsky;Judah Folkman;Robert Sullivan;Rafael Fridman

  • Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose

    Peter V. Hauschka;Athanasios E. Mavrakos;Mark D. Iafrati;Susan E. Doleman

  • Heparin affinity: purification of a tumor-derived capillary endothelial cell growth factor

    Y Shing;J Folkman;R Sullivan;C Butterfield

  • A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane.

    J Folkman;M Klagsbrun;J Sasse;M Wadzinski

  • Heparin-binding EGF-like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: a possible ligand for interaction with blastocyst EGF-receptor in implantation

    S. K. Das;Xiao-Ning Wang;B. C. Paria;D. Damm

  • Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules.

    Pnina Bashkin;Susan Doctrow;Michael Klagsbrun;Carl Magnus Svahn

  • A dual receptor system is required for basic fibroblast growth factor activity

    Michael Klagsbrun;Andrew Baird

  • Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma

    J. Kandel;E. Bossy-Wetzel;F. Radvanyi;M. Klagsbrun

  • Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165.

    Hua-Quan Miao;Shay Soker;Leonard Feiner;José Luis Alonso

  • VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding.

    Shay Soker;Hua-Quan Miao;Masashi Nomi;Seiji Takashima

  • High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons.

    H Prats;M Kaghad;A C Prats;M Klagsbrun

  • Vascular endothelial growth factor and its receptors.

    Michael Klagsbrun;Patricia A. D'Amore

  • HEPARIN-BINDING EGF-LIKE GROWTH FACTOR

    Gerhard Raab;Michael Klagsbrun

  • VASCULOGENESIS, ANGIOGENESIS, AND GROWTH FACTORS : EPHRINS ENTER THE FRAY AT THE BORDER

    George D Yancopoulos;Michael Klagsbrun;Judah Folkman

  • Increased basic fibroblast growth factor (bFGF) immunoreactivity at the site of focal brain wounds.

    Seth P. Finklestein;Paul J. Apostolides;Cornelio G. Caday;Cornelio G. Caday;James Prosser

  • Tumor-Associated Endothelial Cells with Cytogenetic Abnormalities

    Kyoko Hida;Yasuhiro Hida;Dhara N. Amin;Alan F. Flint

Frequent Co-Authors

Judah Folkman
Judah Folkman Boston Children's Hospital
Shay Soker
Shay Soker Wake Forest University
Klaus Elenius
Klaus Elenius University of Turku
Michael R. Freeman
Michael R. Freeman Cedars-Sinai Medical Center
Marsha A. Moses
Marsha A. Moses Boston Children's Hospital
Patricia A. D'Amore
Patricia A. D'Amore Massachusetts Eye and Ear Infirmary
Shigeki Higashiyama
Shigeki Higashiyama Ehime University
Akiko Mammoto
Akiko Mammoto Medical College of Wisconsin
Israel Vlodavsky
Israel Vlodavsky Technion – Israel Institute of Technology
Donald E. Ingber
Donald E. Ingber Harvard University

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