What is she best known for?
The fields of study she is best known for:
- Cancer
- Internal medicine
- Signal transduction
Cell biology, Extracellular matrix, Immunology, Cell and Mechanotransduction are her primary areas of study.
Her Cell biology research is multidisciplinary, incorporating elements of Mechanosensitive channels and Cell fate determination.
Her work focuses on many connections between Mechanosensitive channels and other disciplines, such as Endothelial stem cell, that overlap with her field of interest in Transient receptor potential channel and Integrin.
Her Sepsis study in the realm of Immunology connects with subjects such as Mannan-binding lectin.
Her work on Cytoskeleton as part of general Cell research is often related to Self-healing hydrogels, thus linking different fields of science.
She focuses mostly in the field of Mechanotransduction, narrowing it down to topics relating to Angiogenesis and, in certain cases, Vascular endothelial growth factor A, Actin cytoskeleton, Tumor-Derived, Tumor microenvironment and Rho-associated protein kinase.
Her most cited work include:
- Reconstituting Organ-Level Lung Functions on a Chip (2021 citations)
- A mechanosensitive transcriptional mechanism that controls angiogenesis (405 citations)
- Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein (401 citations)
What are the main themes of her work throughout her whole career to date?
Her primary areas of study are Cell biology, Angiogenesis, Cancer research, Pathology and Extracellular matrix.
In her research, GTPase is intimately related to Cytoskeleton, which falls under the overarching field of Cell biology.
Her Angiogenesis research includes themes of Endothelial stem cell, Wnt signaling pathway, LRP5 and Regeneration.
Her Pathology study integrates concerns from other disciplines, such as Endothelium, Lung injury and Vascular endothelial growth factor, Angiopoietin.
In Extracellular matrix, Akiko Mammoto works on issues like Cell fate determination, which are connected to Mesenchyme.
Her work carried out in the field of Lung brings together such families of science as Inflammation and Immunology.
She most often published in these fields:
- Cell biology (63.79%)
- Angiogenesis (30.17%)
- Cancer research (15.52%)
What were the highlights of her more recent work (between 2015-2021)?
- Cell biology (63.79%)
- Angiogenesis (30.17%)
- Cancer research (15.52%)
In recent papers she was focusing on the following fields of study:
Her primary scientific interests are in Cell biology, Angiogenesis, Cancer research, Pathology and Lung.
In the field of Cell biology, her study on Mesenchymal stem cell overlaps with subjects such as Snail.
The Angiogenesis study combines topics in areas such as Endothelial stem cell, Receptor and Regeneration.
Her studies deal with areas such as Blood vessel and Cell growth as well as Endothelial stem cell.
Her studies examine the connections between Cancer research and genetics, as well as such issues in Gene knockdown, with regards to Pulmonary artery, Growth factor and Adipose tissue.
Her research in Pathology intersects with topics in Endothelium and Phosphorylation.
Between 2015 and 2021, her most popular works were:
- Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip (168 citations)
- Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics (105 citations)
- Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail. (58 citations)
In her most recent research, the most cited papers focused on:
- Cancer
- Internal medicine
- Signal transduction
Akiko Mammoto spends much of her time researching Cell biology, Pathology, Pathogenesis, Phosphorylation and Endothelial stem cell.
Her studies in Cell biology integrate themes in fields like In vitro, Glomerulus and Immunology.
Her Immunology research includes elements of Tissue engineering, Kidney and Induced pluripotent stem cell.
Her biological study spans a wide range of topics, including Whole blood and Endothelium.
Her research integrates issues of Transforming growth factor, SMAD, Hypoxia and Pulmonary hypertension in her study of Pathogenesis.
Her Endothelial stem cell research incorporates themes from Angiogenesis, Cell growth and Mechanosensitive channels.
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