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D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
18844
World Ranking
8115
National Ranking
3672

Overview

Joseph E. Italiano is affiliated with Boston Children's Hospital in the United States. Their research primarily spans the field of Medicine, with notable contributions in Hematology, Genetics, Immunology, Pulmonary and Respiratory Medicine, and Molecular Biology.

Their work frequently addresses key topics including:

  • Platelet Disorders and Treatments
  • Blood properties and coagulation
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Mechanical Circulatory Support Devices
  • Cell Adhesion Molecules Research
  • Blood groups and transfusion
  • Antiplatelet Therapy and Cardiovascular Diseases

Joseph E. Italiano has published extensively, with a significant number of papers appearing in leading journals such as Blood, Blood Advances, bioRxiv (Cold Spring Harbor Laboratory), Arteriosclerosis Thrombosis and Vascular Biology, and Circulation Research.

Some recent notable papers include:

  • "Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation," 2020, Blood Advances
  • "Platelet Activation via Shear Stress Exposure Induces a Differing Pattern of Biomarkers of Activation versus Biochemical Agonists," 2020, Thrombosis and Haemostasis
  • "The bone marrow is the primary site of thrombopoiesis," 2023, Blood
  • "Platelet Dysfunction and Thrombosis in JAK2 V617F -Mutated Primary Myelofibrotic Mice," 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • "Platelet Dysfunction During Mechanical Circulatory Support," 2021, Arteriosclerosis Thrombosis and Vascular Biology

Joseph E. Italiano has collaborated frequently with other researchers, including:

  • Isabelle C. Becker
  • Kellie R. Machlus
  • Yana Roka-Moiia
  • Marvin J. Slepian
  • Estelle Carminita

Best Publications

  • Platelets and the immune continuum

    John W. Semple;Joseph E. Italiano;Joseph E. Italiano;John Freedman;John Freedman

  • Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet α granules and differentially released

    Joseph E. Italiano;Joseph E. Italiano;Jennifer L. Richardson;Sunita Patel-Hett;Sunita Patel-Hett;Elisabeth Battinelli;Elisabeth Battinelli

  • The incredible journey: From megakaryocyte development to platelet formation

    Kellie R. Machlus;Kellie R. Machlus;Joseph E. Italiano;Joseph E. Italiano;Joseph E. Italiano

  • Dynamic Visualization of Thrombopoiesis Within Bone Marrow

    Tobias Junt;Harald Schulze;Zhao Chen;Steffen Massberg

  • The biogenesis of platelets from megakaryocyte proplatelets

    Sunita R. Patel;John H. Hartwig;Joseph E. Italiano

  • Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes.

    Joseph E. Italiano;Patrick Lecine;Ramesh A. Shivdasani;John H. Hartwig;John H. Hartwig

  • Platelets actively sequester angiogenesis regulators

    Giannoula Lakka Klement;Giannoula Lakka Klement;Tai-Tung Yip;Flavia Cassiola;Lena Kikuchi

  • Release of angiogenesis regulatory proteins from platelet alpha granules: modulation of physiologic and pathologic angiogenesis.

    Elisabeth M. Battinelli;Elisabeth M. Battinelli;Beth A. Markens;Beth A. Markens;Joseph E. Italiano;Joseph E. Italiano;Joseph E. Italiano

  • Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles

    Robert Flaumenhaft;James R. Dilks;Jennifer Richardson;Eva Alden

  • Cytoskeletal mechanics of proplatelet maturation and platelet release

    Jonathan Noah Thon;Jonathan Noah Thon;Alejandro Montalvo;Sunita Patel-Hett;Sunita Patel-Hett;Sunita Patel-Hett;Matthew T. Devine

  • Clinical relevance of microparticles from platelets and megakaryocytes.

    Joseph E. Italiano;Albert T.A. Mairuhu;Robert Flaumenhaft

  • A lineage-restricted and divergent β-tubulin isoform is essential for the biogenesis, structure and function of blood platelets

    Heinz D Schwer;Patrick Lecine;Sanjay Tiwari;Joseph E Italiano

  • Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes

    Sunita R. Patel;Jennifer L. Richardson;Jennifer L. Richardson;Harald Schulze;Harald Schulze;Eden Kahle;Eden Kahle

  • Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation

    Kellie R. Machlus;Jonathan N. Thon;Joseph E. Italiano;Joseph E. Italiano;Joseph E. Italiano

  • Platelets: Production, Morphology and Ultrastructure

    Jonathan N. Thon;Jonathan N. Thon;Joseph E. Italiano;Joseph E. Italiano;Joseph E. Italiano

  • IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs.

    Satoshi Nishimura;Satoshi Nishimura;Satoshi Nishimura;Mika Nagasaki;Shinji Kunishima;Akira Sawaguchi

  • Mechanisms of organelle transport and capture along proplatelets during platelet production

    Jennifer L. Richardson;Ramesh A. Shivdasani;Chad Boers;John H. Hartwig

  • VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients

    Jon E. Peterson;David Zurakowski;Joseph E. Italiano;Joseph E. Italiano;Lea V. Michel;Lea V. Michel

  • Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells

    Qiang Feng;Namrata Shabrani;Jonathan N. Thon;Hongguang Huo

  • Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis.

    Alexander Zaslavsky;Kwan-Hyuck Baek;Kwan-Hyuck Baek;Ryan C. Lynch;Sarah Short

Frequent Co-Authors

John H. Hartwig
John H. Hartwig Brigham and Women's Hospital
Ramesh A. Shivdasani
Ramesh A. Shivdasani Harvard University
Robert Flaumenhaft
Robert Flaumenhaft Beth Israel Deaconess Medical Center
Judah Folkman
Judah Folkman Boston Children's Hospital
Andrew S. Weyrich
Andrew S. Weyrich University of Utah
Peter A. Nigrovic
Peter A. Nigrovic Boston Children's Hospital
John W. Semple
John W. Semple Lund University
Hans H. Wandall
Hans H. Wandall University of Copenhagen
Barry H. Paw
Barry H. Paw Brigham and Women's Hospital
Katya Ravid
Katya Ravid Boston University

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