World's Best Scientists 2026 revealed!
John W. Semple

John W. Semple

D-Index & Metrics

Immunology

D-Index
60
Citations
13474
World Ranking
3325
National Ranking
72

Overview

John W. Semple is affiliated with Lund University in Sweden and has a significant research focus in the field of medicine, with a specialization in hematology. Their scholarly output includes a substantial number of publications, with 52 specifically in hematology, and additional work in genetics, immunology, biochemistry, and pulmonary and respiratory medicine.

The main topics of John W. Semple's research center on platelet disorders and treatments, blood groups and transfusion, and blood transfusion management. Other notable research areas include cell adhesion molecules, blood disorders and treatments, blood properties and coagulation, and autoimmune bullous skin diseases.

Frequent publication venues feature several well-known journals in hematology and transfusion medicine. These include:

  • Blood
  • Transfusion
  • Transfusion Medicine Reviews
  • British Journal of Haematology
  • Pathology

John W. Semple has collaborated extensively with several researchers. Frequent co-authors are:

  • Rick Kapur
  • Johan Rebetz
  • Geneviève Marcoux
  • Leendert Porcelijn
  • Saskia van der Velden

Their recent notable publications include the following:

  • "Thrombocytopenia following Pfizer and Moderna SARS-CoV-2 vaccination" (2021) published in American Journal of Hematology
  • "The Immune Nature of Platelets Revisited" (2020) published in Transfusion Medicine Reviews
  • "Recent advances in the mechanisms and treatment of immune thrombocytopenia" (2022) published in EBioMedicine
  • "An update on the pathophysiology of immune thrombocytopenia" (2020) published in Current Opinion in Hematology
  • "Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules" (2021) published in Blood

Best Publications

  • Platelets and the immune continuum

    John W. Semple;Joseph E. Italiano;Joseph E. Italiano;John Freedman;John Freedman

  • Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

    Luc H. Boudreau;Anne Claire Duchez;Nathalie Cloutier;Denis Soulet

  • Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo

    Rukhsana Aslam;Edwin R. Speck;Michael Kim;Andrew R. Crow

  • Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP)

    Anne Zufferey;Rick Kapur;Rick Kapur;John W Semple

  • Differences in Serum Cytokine Levels in Acute and Chronic Autoimmune Thrombocytopenic Purpura: Relationship to Platelet Phenotype and Antiplatelet T-cell Reactivity

    John W. Semple;Youli Milev;Donna Cosgrave;Meera Mody

  • Platelets and innate immunity

    John W Semple;John Freedman

  • Thrombocytopenia following Pfizer and Moderna SARS-CoV-2 vaccination.

    Eun Ju Lee;Douglas B. Cines;Terry Gernsheimer;Craig Kessler

  • Transfusion-associated circulatory overload and transfusion-related acute lung injury.

    John W. Semple;Johan Rebetz;Rick Kapur

  • Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia.

    John W. Semple;John Freedman

  • T granules in human platelets function in TLR9 organization and signaling

    Jonathan N. Thon;Christopher G. Peters;Kellie R. Machlus;Kellie R. Machlus;Rukhsana Aslam

  • A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy

    Leola Chow;Leola Chow;Rukhsana Aslam;Rukhsana Aslam;Edwin R. Speck;Edwin R. Speck;Michael Kim

  • Nouvelle Cuisine: Platelets Served with Inflammation

    Rick Kapur;Anne Zufferey;Eric Boilard;John W Semple

  • Cellular immune dysfunction in immune thrombocytopenia (ITP).

    Christopher G. J. McKenzie;Li Guo;John Freedman;John W. Semple

  • HLA alloimmunization against platelet transfusions: pathophysiology, significance, prevention and management.

    Katerina Pavenski;John Freedman;J W Semple

  • The Immune Nature of Platelets Revisited.

    Amal Maouia;Johan Rebetz;Rick Kapur;John W. Semple

  • Platelet-bound lipopolysaccharide enhances Fc receptor–mediated phagocytosis of IgG-opsonized platelets

    John W. Semple;Rukhsana Aslam;Michael Kim;Edwin R. Speck

  • Cellular immune mechanisms in autoimmune thrombocytopenic purpura: An update.

    Malini D. Coopamah;M. Bernadette Garvey;John Freedman;John W. Semple

  • Pathogenesis of immune thrombocytopenia

    Douglas B Cines;Adam Cuker;John W Semple

  • Immune pathophysiology of autoimmune thrombocytopenic purpura.

    J.W. Semple

  • IVIg inhibits reticuloendothelial system function and ameliorates murine passive-immune thrombocytopenia independent of anti-idiotype reactivity.

    Andrew R. Crow;Seng Song;John W. Semple;John Freedman;John Freedman

Frequent Co-Authors

John Freedman
John Freedman University of Toronto
Heyu Ni
Heyu Ni University of Toronto
Terry L. Delovitch
Terry L. Delovitch University of Western Ontario
Joseph E. Italiano
Joseph E. Italiano Boston Children's Hospital
Douglas B. Cines
Douglas B. Cines University of Pennsylvania
James B. Bussel
James B. Bussel Cornell University
Robert Flaumenhaft
Robert Flaumenhaft Beth Israel Deaconess Medical Center
Eithan Galun
Eithan Galun Hebrew University of Jerusalem
Henrik Clausen
Henrik Clausen University of Copenhagen
Daniel Shouval
Daniel Shouval Hebrew University of Jerusalem

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in immunology, expanding into related healthcare fields can offer diverse career opportunities. Many aspiring professionals explore accelerated nursing programs, which provide a fast track to becoming a registered nurse. These programs are designed for individuals with a non-nursing background, making them accessible for career changers.

Online ABSN programs for non nurses are particularly popular, as they combine flexibility with rigorous training to prepare students for high-demand roles in healthcare. Such programs often serve as a solid foundation for further specialization, including advanced practice roles.

For those seeking a quicker entry into nursing, many look into accelerated nurse practitioner programs. These are ideal for those wanting advanced clinical roles in healthcare, allowing for a deeper engagement with patient care and medical research, which can complement an immunology background.

Additionally, LPN schools easy to get into provide essential nursing education and practical skills. These programs can serve as stepping stones to higher nursing qualifications or specialized areas related to immunology and healthcare research.

Exploring these pathways can enhance one’s knowledge and open new professional avenues.

Learn more about accelerated nurse practitioner programs, online ABSN programs for non nurses, accelerated nursing programs, and LPN schools easy to get into.

Best Scientists Citing John W. Semple

Trending Scientists

Recently Published Articles