D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 66 Citations 12,930 236 World Ranking 1857 National Ranking 40

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Immune system
  • Platelet

His primary scientific interests are in Immunology, Platelet, Immune system, Antibody and Cell biology. His Immunology research is multidisciplinary, relying on both Receptor and Internal medicine. John Freedman does research in Platelet, focusing on Platelet activation specifically.

John Freedman has included themes like Signal transduction and Platelet transfusion in his Immune system study. In his research on the topic of Antibody, Immunoglobulin E, Thrombocytopenic purpura and Immunoglobulin G is strongly related with Immunotherapy. His Cell biology research includes elements of Apoptosis and Monocyte.

His most cited work include:

  • Platelets and the immune continuum. (954 citations)
  • Platelets and the immune continuum. (954 citations)
  • Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo (358 citations)

What are the main themes of his work throughout his whole career to date?

John Freedman focuses on Immunology, Platelet, Antibody, Immune system and Platelet activation. His Immunology study frequently intersects with other fields, such as Internal medicine. His Platelet research incorporates elements of Apoptosis, Fibrinogen, Molecular biology and Cell biology.

As part of one scientific family, John Freedman deals mainly with the area of Antibody, narrowing it down to issues related to the Receptor, and often Mechanism of action. His research in Immune system intersects with topics in Cytotoxic T cell and Human leukocyte antigen. His study looks at the relationship between Platelet activation and topics such as Flow cytometry, which overlap with In vivo.

He most often published in these fields:

  • Immunology (79.46%)
  • Platelet (80.06%)
  • Antibody (49.11%)

What were the highlights of his more recent work (between 2011-2020)?

  • Platelet (80.06%)
  • Immunology (79.46%)
  • Apoptosis (19.05%)

In recent papers he was focusing on the following fields of study:

John Freedman mostly deals with Platelet, Immunology, Apoptosis, Cell biology and Platelet activation. His Platelet research is mostly focused on the topic Platelet transfusion. As part of his studies on Immunology, John Freedman frequently links adjacent subjects like Neonatal alloimmune thrombocytopenia.

His Apoptosis research includes themes of Stimulation, Calcium and Depolarization. His study looks at the relationship between Platelet activation and fields such as Receptor, as well as how they intersect with chemical problems. His Autoimmunity and Antigen-presenting cell study in the realm of Immune system interacts with subjects such as Epiphenomenon.

Between 2011 and 2020, his most popular works were:

  • Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia (148 citations)
  • Cellular immune dysfunction in immune thrombocytopenia (ITP). (121 citations)
  • Plasma fibronectin supports hemostasis and regulates thrombosis (103 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Immune system
  • Antibody

John Freedman mainly investigates Platelet, Immunology, Apoptosis, Cell biology and Platelet activation. John Freedman studies Platelet, focusing on Thromboelastography in particular. The Immunology study which covers Fetus that intersects with Miscarriage.

His Antibody research focuses on Spleen and how it connects with Antigen, Chemokine and Endocrinology. His Inner mitochondrial membrane research incorporates themes from Programmed cell death, Stimulation, Depolarization, Membrane potential and Thrombin. John Freedman is involved in the study of Immune system that focuses on Immunity in particular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Platelets and the immune continuum

John W. Semple;Joseph E. Italiano;Joseph E. Italiano;John Freedman;John Freedman.
Nature Reviews Immunology (2011)

1562 Citations

Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo

Rukhsana Aslam;Edwin R. Speck;Michael Kim;Andrew R. Crow.
Blood (2006)

540 Citations

Differences in Serum Cytokine Levels in Acute and Chronic Autoimmune Thrombocytopenic Purpura: Relationship to Platelet Phenotype and Antiplatelet T-cell Reactivity

John W. Semple;Youli Milev;Donna Cosgrave;Meera Mody.
Blood (1996)

455 Citations

Platelets and innate immunity

John W Semple;John Freedman.
Cellular and Molecular Life Sciences (2010)

369 Citations

Proceedings of a consensus conference : Towards an understanding of TRALI

Mindy Goldman;Kathryn E. Webert;Donald M. Arnold;John Freedman.
Transfusion Medicine Reviews (2005)

306 Citations

INTRAVENOUS IMMUNOGLOBULIN AMELIORATES ITP VIA ACTIVATING FC GAMMA RECEPTORS ON DENDRITIC CELLS

Vinayakumar Siragam;Andrew R Crow;Andrew R Crow;Davor Brinc;Davor Brinc;Seng Song.
Nature Medicine (2006)

303 Citations

Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia

June Li;Dianne E. van der Wal;Guangheng Zhu;Miao Xu.
Nature Communications (2015)

251 Citations

Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia.

John W. Semple;John Freedman.
Blood (1991)

230 Citations

Platelets in hemostasis and thrombosis: role of integrins and their ligands.

Heyu Ni;John Freedman.
Transfusion and Apheresis Science (2003)

197 Citations

A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy

Leola Chow;Leola Chow;Rukhsana Aslam;Rukhsana Aslam;Edwin R. Speck;Edwin R. Speck;Michael Kim.
Blood (2010)

188 Citations

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