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D-Index & Metrics

Immunology

D-Index
73
Citations
16580
World Ranking
2154
National Ranking
45

Medicine

D-Index
73
Citations
16658
World Ranking
19704
National Ranking
834

Overview

John Freedman is affiliated with the University of Toronto in Canada and specializes primarily in the field of Medicine. Their research spans several subfields including Hematology, Biochemistry, Critical Care and Intensive Care Medicine, Internal Medicine, and Nephrology.

The scientific inquiry by Freedman frequently addresses key topics such as Platelet Disorders and Treatments, Blood Transfusion and Management, Trauma, Hemostasis, Coagulopathy, Resuscitation, Venous Thromboembolism Diagnosis and Management, Renal Diseases and Glomerulopathies, Blood Groups and Transfusion, and Blood Coagulation and Thrombosis Mechanisms.

Freedman's notable publications include:

  • ONTraC: A 20-Year History of a Successfully Coordinated Provincewide Patient Blood Management Program: Lessons Learned and Goals Achieved (2022) published in Anesthesia & Analgesia
  • Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression (2023) published in Research
  • Plasma fibronectin supports hemostasis and regulates thrombosis (2020) published in UNC Libraries
  • Oral iron versus intravenous iron for preoperative anemia management: the ONTraC experience (2020) published in Transfusion Medicine Reviews
  • OA4-AM23-SN-05 | Let's Talk About Sex: Females Experience Greater Perioperative Anemia and Higher Transfusion Rates in Major Elective Surgery (2023) published in Transfusion

Frequent collaborators in Freedman's research include Katerina Pavenski, Alanna Howell, Heyu Ni, Yulia Lin, and Lee Vernich.

The preferred publication venues for Freedman's work include Anesthesia & Analgesia, Research, UNC Libraries, Transfusion Medicine Reviews, and Transfusion.

Best Publications

  • Platelets and the immune continuum

    John W. Semple;Joseph E. Italiano;Joseph E. Italiano;John Freedman;John Freedman

  • Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo

    Rukhsana Aslam;Edwin R. Speck;Michael Kim;Andrew R. Crow

  • Differences in Serum Cytokine Levels in Acute and Chronic Autoimmune Thrombocytopenic Purpura: Relationship to Platelet Phenotype and Antiplatelet T-cell Reactivity

    John W. Semple;Youli Milev;Donna Cosgrave;Meera Mody

  • Platelets and innate immunity

    John W Semple;John Freedman

  • Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia

    June Li;Dianne E. van der Wal;Guangheng Zhu;Miao Xu

  • Proceedings of a consensus conference : Towards an understanding of TRALI

    Mindy Goldman;Kathryn E. Webert;Donald M. Arnold;John Freedman

  • Multimodal Patient Blood Management Program Based on a Three-pillar Strategy: A Systematic Review and Meta-analysis.

    Friederike C Althoff;Holger Neb;Eva Herrmann;Kevin M Trentino

  • INTRAVENOUS IMMUNOGLOBULIN AMELIORATES ITP VIA ACTIVATING FC GAMMA RECEPTORS ON DENDRITIC CELLS

    Vinayakumar Siragam;Andrew R Crow;Andrew R Crow;Davor Brinc;Davor Brinc;Seng Song

  • Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia.

    John W. Semple;John Freedman

  • A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy

    Leola Chow;Leola Chow;Rukhsana Aslam;Rukhsana Aslam;Edwin R. Speck;Edwin R. Speck;Michael Kim

  • Platelets in hemostasis and thrombosis: role of integrins and their ligands.

    Heyu Ni;John Freedman

  • Cellular immune dysfunction in immune thrombocytopenia (ITP).

    Christopher G. J. McKenzie;Li Guo;John Freedman;John W. Semple

  • HLA alloimmunization against platelet transfusions: pathophysiology, significance, prevention and management.

    Katerina Pavenski;John Freedman;J W Semple

  • Plasma fibronectin supports hemostasis and regulates thrombosis

    Yiming Wang;Adili Reheman;Christopher M. Spring;Jalil Kalantari

  • Guidelines on the use of intravenous immune globulin for neurologic conditions.

    Tom Feasby;Brenda Banwell;Timothy Benstead;Vera Bril

  • Platelet-bound lipopolysaccharide enhances Fc receptor–mediated phagocytosis of IgG-opsonized platelets

    John W. Semple;Rukhsana Aslam;Michael Kim;Edwin R. Speck

  • Pathologic high shear stress induces apoptosis events in human platelets.

    Valery Leytin;David J. Allen;David J. Allen;Sergiy Mykhaylov;Sergiy Mykhaylov;Lukasz Mis;Lukasz Mis

  • The Platelet Function Analyzer (PFA‐100®): a novel in‐vitro system for evaluation of primary haemostasis in children

    M D Carcao;V S Blanchette;J A Dean;L He

  • Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbα antibodies

    Michelle Lee Webster;Ebrahim Sayeh;Min Crow;Pingguo Chen

  • Platelet apoptosis in stored platelet concentrates and other models

    Valery Leytin;John Freedman;John Freedman

Frequent Co-Authors

John W. Semple
John W. Semple Lund University
Heyu Ni
Heyu Ni University of Toronto
Hong Yang
Hong Yang University of Illinois at Urbana-Champaign
Marion E. Reid
Marion E. Reid New York Blood Center
Frederick A. Ofosu
Frederick A. Ofosu McMaster University
Zaverio M. Ruggeri
Zaverio M. Ruggeri Scripps Research Institute
Cheng Zhu
Cheng Zhu Georgia Institute of Technology
Morris A. Blajchman
Morris A. Blajchman McMaster University
Patrick Tso
Patrick Tso University of Cincinnati

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