Richard O. Hynes

Research.com Recognitions

• 2025 - Research.com Best Scientists Award
• 2025 - Research.com Biology and Biochemistry in United States Leader Award
• 2023 - Research.com Biology and Biochemistry in United States Leader Award
• 2017 - David Rall Medal, National Academy of Medicine (NAM)
• 2007 - E.B. Wilson Medal, American Society for Cell Biology
• 2007 - Robert J. and Claire Pasarow Foundation Medical Research Award
• 1997 - Canada Gairdner International Award
• 1996 - Member of the National Academy of Sciences
• 1995 - Member of the National Academy of Medicine (NAM)
• 1994 - Fellow of the American Academy of Arts and Sciences
• 1989 - Fellow of the Royal Society, United Kingdom
• 1987 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1982 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Best Publications

• Integrins: versatility, modulation, and signaling in cell adhesion.

  Richard O. Hynes

  19597
  Citations

• Integrins: Bidirectional, Allosteric Signaling Machines

  Richard O. Hynes

  14015
  Citations

• Integrins: a family of cell surface receptors.

  Richard O. Hynes

  6630
  Citations

• The Extracellular Matrix: Not Just Pretty Fibrils

  Richard O. Hynes

  4352
  Citations

• A framework for advancing our understanding of cancer-associated fibroblasts

  Erik Sahai;Igor Astsaturov;Edna Cukierman;David G. DeNardo

  3566
  Citations

• Complete Replication of Hepatitis C Virus in Cell Culture

  Brett D. Lindenbach;Brett D. Lindenbach;Brett D. Lindenbach;Matthew J. Evans;Matthew J. Evans;Matthew J. Evans;Andrew J. Syder;Andrew J. Syder;Andrew J. Syder;Benno Wölk;Benno Wölk;Benno Wölk

  2801
  Citations

• Genomic analysis of metastasis reveals an essential role for RhoC

  Edwin A. Clark;Todd R. Golub;Todd R. Golub;Eric S. Lander;Richard O. Hynes;Richard O. Hynes

  2194
  Citations

• Comparative Genomics of the Eukaryotes

  Gerald M. Rubin;Mark D. Yandell;Jennifer R. Wortman;George L. Gabor

  2161
  Citations

• Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin

  Elizabeth L. George;Elisabeth N. Georges-Labouesse;Ramila S. Patel-King;Helen Rayburn

  1798
  Citations

• Fibronectins: multifunctional modular glycoproteins.

  R O Hynes;K M Yamada

  1604
  Citations

• Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

  Myriam Labelle;Shahinoor Begum;Richard O. Hynes

  1562
  Citations

• Thrombospondin-1 Is a Major Activator of TGF-β1 In Vivo

  Susan E Crawford;Susan E Crawford;Veronica Stellmach;Joanne E Murphy-Ullrich;Solange M.F Ribeiro

  1518
  Citations

• Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

  Tanya N. Mayadas;Robert C. Johnson;Helen Rayburn;Richard O. Hynes

  1350
  Citations

• Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons

  Richard O. Hynes;Arthur D. Lander

  1290
  Citations

• The genome of the sea urchin Strongylocentrotus purpuratus.

  Erica Sodergren;George M. Weinstock;Eric H. Davidson;R. Andrew Cameron

  1289
  Citations

• Overview of the Matrisome—An Inventory of Extracellular Matrix Constituents and Functions

  Richard O. Hynes;Alexandra Naba

  1268
  Citations

• Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

  David Lyden;Alison Z. Young;David Zagzag;Wei Yan

  1180
  Citations

• The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices

  Alexandra Naba;Karl R. Clauser;Sebastian Hoersch;Sebastian Hoersch;Hui Liu

  1168
  Citations

• Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development

  J.T. Yang;H. Rayburn;R.O. Hynes

  1165
  Citations

• Structure of Integrin, a Glycoprotein Involved in the Transmembrane Linkage between Fibronectin and Actin

  John W. Tamkun;Douglas W. DeSimone;Deborah Fonda;Ramila S. Patel

  1136
  Citations