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Microbiology

D-Index
88
Citations
28250
World Ranking
759
National Ranking
41

Overview

Patrick Berche is affiliated with Université Paris Cité in France and has an active research profile emphasizing molecular biology, microbiology, and infectious diseases. Their work spans multiple disciplines including biochemistry, genetics, molecular biology, medicine, immunology, and microbiology, reflecting a multidisciplinary approach to studying bacterial pathogens and host interactions.

Among the main subfields of their research are molecular biology, microbiology, infectious diseases, genetics, and epidemiology. These areas underpin their investigation into microbial behavior, bacterial genetics, and mechanisms of infection. Their research focuses on topics such as bacterial infections and vaccines, bacterial genetics and biotechnology, bacteriophages and microbial interactions, RNA and protein synthesis mechanisms, antibiotic resistance in bacteria, protein tyrosine phosphatases, and Escherichia coli studies.

Recent publications highlight diverse aspects of microbial pathogenesis and clinical microbiology. Key papers include:

  • Surging bloodstream infections and antimicrobial resistance during the first wave of COVID-19: a study in a large multihospital institution in the Paris region (2021) - International Journal of Infectious Diseases
  • Performance of clinical metagenomics in France: a prospective observational study (2023) - The Lancet Microbe
  • The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus (2021) - Proceedings of the National Academy of Sciences
  • Meningococcal disease: A paradigm of type-IV pilus dependent pathogenesis (2020) - Cellular Microbiology
  • Receptor recognition by meningococcal type IV pili relies on a specific complex N-glycan (2020) - Proceedings of the National Academy of Sciences

Publications have appeared frequently in venues such as:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Infectious Diseases
  • International Journal of Infectious Diseases
  • The Lancet Microbe

Collaborations form an integral part of Berche's research activity, with frequent co-authors including Mathieu Coureuil, Julie Meyer, Emmanuelle Bille, Anne Jamet, and Sandrine Bourdoulous. These partnerships indicate a collaborative research environment focused on bacterial pathogenesis and molecular microbiology.

Best Publications

  • Listeria pathogenesis and molecular virulence determinants.

    José A. Vázquez-Boland;José A. Vázquez-Boland;Michael Kuhn;Patrick Berche;Trinad Chakraborty

  • Comparative Genomics of Listeria Species

    P Glaser;L Frangeul;C Buchrieser;C Rusniok

  • L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein.

    C. Kocks;E. Gouin;M. Tabouret;P. Berche

  • Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci

    J.-L. Gaillard;P. Berche;C. Frehel;E. Gouln

  • In vitro model of penetration and intracellular growth of Listeria monocytogenes in the human enterocyte-like cell line Caco-2.

    J L Gaillard;P Berche;J Mounier;S Richard

  • Transposon mutagenesis as a tool to study the role of hemolysin in the virulence of Listeria monocytogenes.

    J L Gaillard;P Berche;P Sansonetti

  • Listeriolysin O is essential for virulence of Listeria monocytogenes: direct evidence obtained by gene complementation.

    P Cossart;M F Vicente;J Mengaud;F Baquero

  • Purification, characterization, and toxicity of the sulfhydryl-activated hemolysin listeriolysin O from Listeria monocytogenes.

    C Geoffroy;J L Gaillard;J E Alouf;P Berche

  • Contribution of individual toxin components to virulence of Bacillus anthracis.

    C Pezard;P Berche;M Mock

  • Identification of streptococci to species level by sequencing the gene encoding the manganese-dependent superoxide dismutase

    Claire Poyart;Gilles Quesne;Stephane Coulon;Patrick Berche

  • hsp65 Sequencing for Identification of Rapidly Growing Mycobacteria

    H. Ringuet;C. Akoua-Koffi;S. Honore;A. Varnerot

  • Human listeriosis caused by Listeria ivanovii.

    Christelle Guillet;Olivier Join-Lambert;Alban Le Monnier;Alexandre Leclercq

  • Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes.

    Eric Abachin;Claire Poyart;Elisabeth Pellegrini;Eliane Milohanic

  • Immunoproliferative Small Intestinal Disease Associated with Campylobacter jejuni

    Marc Lecuit;Eric Abachin;Antoine Martin;Claire Poyart;Claire Poyart;Claire Poyart

  • The ClpP serine protease is essential for the intracellular parasitism and virulence of Listeria monocytogenes

    Olivier Gaillot;Elisabeth Pellegrini;Søren Bregenholt;Shamila Nair

  • Possible role of catheters in Saccharomyces boulardii fungemia.

    C. Hennequin;C. Kauffmann-Lacroix;A. Jobert;J. P. Viard

  • Real-Time Identification of Bacteria and Candida Species in Positive Blood Culture Broths by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry

    Agnès Ferroni;Stéphanie Suarez;Jean-Luc Beretti;Brunhilde Dauphin

  • Rapid Identification of Staphylococci Isolated in Clinical Microbiology Laboratories by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry

    Etienne Carbonnelle;Jean Luc Beretti;Stéphanie Cottyn;Gilles Quesne

  • Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by single amino acid substitutions in listeriolysin O.

    E. Michel;K. A. Reich;R. Favier;P. Berche

  • Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Nonfermenting Gram-Negative Bacilli Isolated from Cystic Fibrosis Patients

    Nicolas Degand;Nicolas Degand;Etienne Carbonnelle;Etienne Carbonnelle;Brunhilde Dauphin;Jean-Luc Beretti

Frequent Co-Authors

Jean-Louis Gaillard
Jean-Louis Gaillard Hôpital Ambroise-Paré
Claire Poyart
Claire Poyart Institut Cochin
Alain Charbit
Alain Charbit Université Paris Cité
Patrick Trieu-Cuot
Patrick Trieu-Cuot Institut Pasteur
Xavier Nassif
Xavier Nassif Université Paris Cité
Isabelle Sermet-Gaudelus
Isabelle Sermet-Gaudelus Necker-Enfants Malades Hospital
Pascale Cossart
Pascale Cossart Institut Pasteur
Marc Lecuit
Marc Lecuit Institut Pasteur
José A. Vázquez-Boland
José A. Vázquez-Boland University of Edinburgh

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