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Genetics

D-Index
76
Citations
25390
World Ranking
1811
National Ranking
833

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2019 - Member of the National Academy of Sciences
  • 2004 - Fellow of Alfred P. Sloan Foundation

Overview

Harmit S. Malik is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a portfolio comprising 70 publications. Within this broad field, they have contributed notably to molecular biology, plant science, immunology, genetics, and infectious diseases.

Their work covers a range of main topics including chromosomal and genetic variations, interferon and immune responses, CRISPR and genetic engineering, HIV research and treatment, genomics and chromatin dynamics, genetic and clinical aspects of sex determination and chromosomal abnormalities, and bacteriophages and microbial interactions.

Harmit S. Malik's recent publications include:

  • A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Evolutionary Landscapes of Host-Virus Arms Races, 2022, Annual Review of Immunology
  • Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases, 2020, Molecular Cell
  • Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in Drosophila, 2020, eLife
  • A functional map of HIV-host interactions in primary human T cells, 2022, Nature Communications

They frequently publish in venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Molecular Biology and Evolution, PLoS Biology, and Science Advances. These outlets highlight an emphasis on molecular biology and evolutionary studies as well as immunological research.

Collaboration has been a notable aspect of their work. Frequent co-authors include Janet M. Young, Michael Emerman, Jeannette L. Tenthorey, Antoine Molaro, and Tamanash Bhattacharya.

Regarding professional recognition, Harmit S. Malik was named Fellow of the American Association for the Advancement of Science (AAAS) and elected Member of the National Academy of Sciences in 2019. Earlier, in 2004, they were recognized as a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • The centromere paradox: stable inheritance with rapidly evolving DNA.

    Steven Henikoff;Kami Ahmad;Harmit S. Malik

  • Positive selection of primate TRIM5α identifies a critical species-specific retroviral restriction domain

    Sara L. Sawyer;Lily I. Wu;Michael Emerman;Harmit S. Malik

  • Phylogenomics of the nucleosome.

    Harmit S Malik;Steven Henikoff

  • The age and evolution of non-LTR retrotransposable elements.

    H S Malik;W D Burke;T H Eickbush

  • Ancient Adaptive Evolution of the Primate Antiviral DNA-Editing Enzyme APOBEC3G

    Sara Lea Sawyer;Michael Emerman;Harmit S. Malik

  • Rules of Engagement: Molecular Insights from Host-Virus Arms Races

    Matthew D. Daugherty;Harmit S. Malik

  • Poised for contagion: evolutionary origins of the infectious abilities of invertebrate retroviruses.

    Harmit S. Malik;Steve Henikoff;Thomas H. Eickbush

  • Major evolutionary transitions in centromere complexity.

    Harmit S. Malik;Steven Henikoff

  • A unified phylogeny-based nomenclature for histone variants

    Paul B Talbert;Kami Ahmad;Geneviève Almouzni;Juan Ausió

  • Poxviruses deploy genomic accordions to adapt rapidly against host antiviral defenses

    Nels C. Elde;Stephanie J. Child;Michael T. Eickbush;Jacob O. Kitzman

  • Adaptive evolution of Cid, a centromere-specific histone in Drosophila.

    Harmit S. Malik;Steven Henikoff;Steven Henikoff

  • Accelerated evolution of the Prdm9 speciation gene across diverse metazoan taxa

    Peter L. Oliver;Leo Goodstadt;Joshua J. Bayes;Zoë Birtle

  • Safeguarding gene drive experiments in the laboratory

    Omar S. Akbari;Hugo J. Bellen;Ethan Bier;Simon L. Bullock

  • Protein kinase R reveals an evolutionary model for defeating viral mimicry

    Nels C. Elde;Stephanie J. Child;Adam P. Geballe;Adam P. Geballe;Harmit S. Malik

  • The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx

    Efrem S. Lim;Oliver I. Fregoso;Connor O. McCoy;Frederick A. Matsen

  • Guidelines for naming nonprimate APOBEC3 genes and proteins.

    Rebecca S. LaRue;Valgerdur Andrésdóttir;Yannick Blanchard;Silvestro G. Conticello

  • Origins and Evolution of Retrotransposons

    Thomas H. Eickbush;Harmit S. Malik

  • Phylogenetic Analysis of Ribonuclease H Domains Suggests a Late, Chimeric Origin of LTR Retrotransposable Elements and Retroviruses

    Harmit S. Malik;Thomas H. Eickbush

  • Conflict begets complexity: the evolution of centromeres.

    Harmit S Malik;Steven Henikoff

Frequent Co-Authors

Michael Emerman
Michael Emerman Fred Hutchinson Cancer Research Center
Steven Henikoff
Steven Henikoff Fred Hutchinson Cancer Research Center
Thomas H. Eickbush
Thomas H. Eickbush University of Rochester
Barry L. Stoddard
Barry L. Stoddard Fred Hutchinson Cancer Research Center
Gary H. Karpen
Gary H. Karpen University of California, Berkeley
Meng-Chao Yao
Meng-Chao Yao Academia Sinica
Georg Kochs
Georg Kochs University of Freiburg
Adam P. Geballe
Adam P. Geballe Fred Hutchinson Cancer Research Center
Gerald R. Smith
Gerald R. Smith Fred Hutchinson Cancer Research Center
John V. Moran
John V. Moran University of Michigan–Ann Arbor

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