His scientific interests lie mostly in Virology, Capsid, Cell biology, Molecular biology and SAMHD1. His Virology research focuses on Coiled coil and how it relates to Tripartite motif family, Function and Zinc finger. His research integrates issues of Retrovirus and Avidity in his study of Capsid.
His Cell biology research includes elements of Apoptosis, Caspase 1 and Proteolysis. Felipe Diaz-Griffero has researched Molecular biology in several fields, including Mutant, CDC2 Protein Kinase, Phosphorylation, RNA-binding protein and Binding site. His research in SAMHD1 intersects with topics in Cell culture, Viral replication, Origin recognition complex and Kinase.
Felipe Diaz-Griffero mainly focuses on Virology, Cell biology, Capsid, SAMHD1 and Molecular biology. The study of Virology is intertwined with the study of Cell culture in a number of ways. Felipe Diaz-Griffero interconnects Jurkat cells, Mutant and TRIM Family in the investigation of issues within Cell biology.
Felipe Diaz-Griffero has included themes like Cyclophilin A, Plasma protein binding, Reverse transcriptase and Avidity in his Capsid study. The various areas that Felipe Diaz-Griffero examines in his SAMHD1 study include Interferon, Restriction factor, Allosteric regulation and Phosphorylation. The study incorporates disciplines such as Cytoplasm, Mutation, Sterile alpha motif, Wild type and Fusion protein in addition to Molecular biology.
Cell biology, Capsid, SAMHD1, Reverse transcriptase and Cyclophilin A are his primary areas of study. His biological study spans a wide range of topics, including Autophagy, TRIM5alpha and Fusion protein. His Capsid study incorporates themes from Infectivity, Polyadenylation, Binding ability and Cytosol.
His work carried out in the field of Cytosol brings together such families of science as Nucleus and Virology. His studies deal with areas such as Mutant, Nucleotide, Allosteric regulation, Enzyme and Phosphorylation as well as SAMHD1. His study looks at the relationship between Primary cell and topics such as Specificity factor, which overlap with Molecular biology.
The scientist’s investigation covers issues in Cell biology, Capsid, Cell cycle, Transmembrane protein and Phosphorylation. His Cell biology research is multidisciplinary, incorporating perspectives in Jurkat cells and Human cytomegalovirus. His Capsid research is multidisciplinary, relying on both Reverse transcriptase, Primary cell, Cypa, Cyclophilin A and Peripheral blood mononuclear cell.
His Phosphorylation research includes themes of Mitosis and Holoenzymes. His Cell study combines topics from a wide range of disciplines, such as SAMHD1 and Virology. His Virology study combines topics in areas such as Receptor tyrosine kinase, Endocytosis and Intracellular.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5α restriction factor
Matthew Stremlau;Michel Perron;Mark Lee;Yuan Li.
Proceedings of the National Academy of Sciences of the United States of America (2006)
The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation
Tommy E. White;Alberto Brandariz-Nuñez;Jose Carlos Valle-Casuso;Sarah Amie.
Cell Host & Microbe (2013)
Peripheral Blood CCR4 + CCR6 + and CXCR3 + CCR6 + CD4 + T Cells Are Highly Permissive to HIV-1 Infection
Annie Gosselin;Patricia Monteiro;Nicolas Chomont;Felipe Diaz-Griffero.
Journal of Immunology (2010)
The ribonuclease activity of SAMHD1 is required for HIV-1 restriction
Jeongmin Ryoo;Jongsu Choi;Changhoon Oh;Sungchul Kim.
Nature Medicine (2014)
Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5.
Felipe Diaz-Griffero;Xing Li;Hassan Javanbakht;Byeongwoon Song.
The Contribution of RING and B-box 2 Domains to Retroviral Restriction Mediated by Monkey TRIM5α
Hassan Javanbakht;Felipe Diaz-Griffero;Matthew Stremlau;Zhihai Si.
Journal of Biological Chemistry (2005)
A B-Box 2 Surface Patch Important for TRIM5α Self-Association, Capsid Binding Avidity, and Retrovirus Restriction
Felipe Diaz-Griffero;Xu Rong Qin;Fumiaki Hayashi;Takanori Kigawa.
Journal of Virology (2009)
Retroviral Restriction Factor TRIM5α Is a Trimer
Claudia C. Mische;Hassan Javanbakht;Byeongwoon Song;Felipe Diaz-Griffero.
Journal of Virology (2005)
Structural basis of HIV-1 capsid recognition by PF74 and CPSF6
Akash Bhattacharya;Steven L. Alam;Thomas Fricke;Kaneil Zadrozny.
Proceedings of the National Academy of Sciences of the United States of America (2014)
BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells
Mala Mani;Daniel E. Carrasco;Yunyu Zhang;Kohichi Takada.
Cancer Research (2009)
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